Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3t4k | EMU | Histidine kinase 4 | 2.7.13.3 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3t4k | EMU | Histidine kinase 4 | 2.7.13.3 | 1.000 | |
3t4l | ZEA | Histidine kinase 4 | 2.7.13.3 | 0.709 | |
3t4q | ZEA | Histidine kinase 4 | 2.7.13.3 | 0.680 | |
1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.503 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.503 | |
1rc0 | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.500 | |
2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.498 | |
1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.497 | |
1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.496 | |
1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.495 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.489 | |
4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.489 | |
2e2q | ADP | ATP-dependent hexokinase | / | 0.485 | |
3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.483 | |
1osv | CHC | Bile acid receptor | / | 0.482 | |
2gr1 | FAD | Ferredoxin reductase | / | 0.482 | |
2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
3m6g | ATP | Actin, alpha skeletal muscle | / | 0.481 | |
1rby | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.480 | |
5j4e | FMN | Sensory box protein | / | 0.480 | |
1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.478 | |
1sn5 | T3 | Transthyretin | / | 0.478 | |
2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.478 | |
2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.478 | |
1gv0 | NAD | Malate dehydrogenase | / | 0.477 | |
3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.477 | |
4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.477 | |
3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.476 | |
3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.476 | |
4jlt | 8PR | Cytochrome P450 2B4 | 1.14.14.1 | 0.476 | |
2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.475 | |
3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.475 | |
3stv | 3HO | Methylketone synthase I | / | 0.475 | |
5j3w | FMN | Sensory box protein | / | 0.475 | |
4a9t | A9T | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.474 | |
3vqu | O22 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.473 | |
4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.472 | |
3ics | ADP | Coenzyme A disulfide reductase | / | 0.472 | |
1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
1sxj | ADP | Replication factor C subunit 5 | / | 0.471 | |
2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.471 | |
3hv6 | R39 | Mitogen-activated protein kinase 14 | / | 0.471 | |
4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.471 | |
4qe6 | JN3 | Bile acid receptor | / | 0.471 | |
4jay | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.470 | |
1ppj | ANY | Cytochrome b | / | 0.469 | |
1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.469 | |
1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.469 | |
2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.468 | |
3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.468 | |
4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.468 | |
1pvd | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.467 | |
2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
3nxe | 2NC | Protease | / | 0.467 | |
4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.467 | |
4pkh | ADP | Actin, alpha skeletal muscle | / | 0.467 | |
4y93 | 746 | Tyrosine-protein kinase | / | 0.467 | |
1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.466 | |
2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.466 | |
4ks7 | X4Z | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.466 | |
4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.466 | |
1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.465 | |
1ruo | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.465 | |
2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.465 | |
3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.465 | |
4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.465 | |
1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.464 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.464 | |
2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.464 | |
2z3u | CRR | Cytochrome P450 | / | 0.464 | |
3ayg | HQO | Nitric oxide reductase | / | 0.464 | |
3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.464 | |
3nf7 | CIW | Gag-Pol polyprotein | / | 0.464 | |
5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.464 | |
1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.463 | |
1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.463 | |
2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.463 | |
2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
2o4r | VD5 | Vitamin D3 receptor | / | 0.463 | |
2pv7 | NAD | T-protein | 1.3.1.12 | 0.463 | |
2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.463 | |
4fhi | 0S4 | Vitamin D3 receptor A | / | 0.463 | |
4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.463 | |
4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.463 | |
4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.463 | |
4pl8 | ATP | Actin, alpha skeletal muscle | / | 0.463 | |
2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.462 | |
2z6i | FMN | 2-nitropropane dioxygenase | / | 0.462 | |
3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.462 | |
3s56 | ROC | Protease | / | 0.462 | |
4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.462 | |
4ia3 | BIV | Vitamin D3 receptor A | / | 0.462 | |
1bvg | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.461 | |
1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.461 | |
1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.461 | |
2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.461 | |
2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.461 | |
3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
3sw7 | 19K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.461 | |
3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.461 | |
4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.461 | |
5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.461 | |
1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.460 | |
3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.460 | |
3rnn | RNN | Glutamate receptor 2 | / | 0.460 | |
3zuy | TCH | Transporter | / | 0.460 | |
4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.459 | |
1u3c | FAD | Cryptochrome-1 | / | 0.459 | |
1v4s | MRK | Glucokinase | 2.7.1.2 | 0.459 | |
1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.459 | |
2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.459 | |
2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.459 | |
2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.459 | |
3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.459 | |
3p2o | NAD | Bifunctional protein FolD | / | 0.459 | |
3vrw | YS5 | Vitamin D3 receptor | / | 0.459 | |
4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.459 | |
4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.458 | |
1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.458 | |
1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.458 | |
2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.458 | |
3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.458 | |
4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.458 | |
4lb2 | DM5 | Serum albumin | / | 0.458 | |
4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.458 | |
4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
1bws | NDP | GDP-L-fucose synthase | / | 0.457 | |
1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
2bhi | SFT | Cytotoxin 3 | / | 0.457 | |
2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.457 | |
3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.457 | |
3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.457 | |
3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.457 | |
4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.457 | |
4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.457 | |
5ax3 | 5ID | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
1bve | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.456 | |
1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.456 | |
2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
3a9w | NAD | NDP-sugar epimerase | / | 0.456 | |
3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.456 | |
3upj | U03 | Gag-Pol polyprotein | / | 0.456 | |
3w0a | DS5 | Vitamin D3 receptor | / | 0.456 | |
4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.456 | |
4ros | APR | Malate dehydrogenase | / | 0.456 | |
4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.456 | |
5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.456 | |
3rey | XAC | Adenosine receptor A2a | / | 0.456 | |
1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.455 | |
1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.455 | |
1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.455 | |
2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
3b7d | CNI | Glutamate receptor 2 | / | 0.455 | |
3id8 | MRK | Glucokinase | 2.7.1.2 | 0.455 | |
3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.455 | |
3stu | DK3 | Methylketone synthase I | / | 0.455 | |
3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
4fhf | 0TT | Spore photoproduct lyase | / | 0.455 | |
4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.455 | |
4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
1hnj | MLC | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.454 | |
1ie3 | NAD | Malate dehydrogenase | / | 0.454 | |
1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.454 | |
1lot | ATP | Actin, alpha skeletal muscle | / | 0.454 | |
1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.454 | |
2p5u | NAD | UDP-glucose 4-epimerase | / | 0.454 | |
3a1l | 2CC | Cytochrome P450 | / | 0.454 | |
3gob | HXX | DdmC | / | 0.454 | |
3imx | B84 | Glucokinase | 2.7.1.2 | 0.454 | |
3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.454 | |
3oro | AGS | Serine/threonine protein kinase | / | 0.454 | |
3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
3vhk | BPK | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.454 | |
3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.454 | |
4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.454 | |
4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
4wq4 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.454 | |
5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.454 | |
1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.453 | |
1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.453 | |
1z1f | STL | Resveratrol synthase | / | 0.453 | |
2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.453 | |
2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.453 | |
2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.453 | |
3nwz | COA | BH2602 protein | / | 0.453 | |
3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.453 | |
3stw | 2TD | Methylketone synthase I | / | 0.453 | |
4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.453 | |
4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.453 | |
5br7 | FAD | UDP-galactopyranose mutase | / | 0.453 | |
5it1 | 2OH | Putative cytochrome P450 | / | 0.453 | |
5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.452 | |
1efa | NPF | Lactose operon repressor | / | 0.452 | |
2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.452 | |
2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 0.452 | |
2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
2y05 | NAP | Prostaglandin reductase 1 | / | 0.452 | |
3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.452 | |
3cge | COA | Coenzyme A disulfide reductase | / | 0.452 | |
3cp9 | C19 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
3pe6 | ZYH | Monoglyceride lipase | / | 0.452 | |
3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
3sw1 | FMN | Sensory box protein | / | 0.452 | |
3tqh | NDP | Quinone oxidoreductase | / | 0.452 | |
3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.452 | |
4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.452 | |
4d4s | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
4fhh | 0U3 | Vitamin D3 receptor A | / | 0.452 | |
4r9u | ANP | Vitamin B12 import ATP-binding protein BtuD | / | 0.452 | |
4rw4 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.452 | |
4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.452 | |
1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.451 | |
1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.451 | |
2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.451 | |
2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.451 | |
2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.451 | |
3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.451 | |
3d7k | D7K | Benzaldehyde lyase | / | 0.451 | |
3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.451 | |
3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.451 | |
3zok | NAD | 3-dehydroquinate synthase, chloroplastic | 4.2.3.4 | 0.451 | |
4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
4dt9 | GMP | APH(2'')-Id | / | 0.451 | |
4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.451 | |
4ruo | BIV | Vitamin D3 receptor A | / | 0.451 | |
4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.451 | |
5dp2 | NAP | CurF | / | 0.451 | |
1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.450 | |
1fml | RTL | Retinol dehydratase | / | 0.450 | |
1gqt | ACP | Ribokinase | / | 0.450 | |
1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
1rdw | LAR | Actin, alpha skeletal muscle | / | 0.450 | |
1u2o | NEC | Endoplasmin | / | 0.450 | |
1w2x | RCP | Acetyl-CoA carboxylase | / | 0.450 | |
1zem | NAD | Xylitol dehydrogenase | / | 0.450 | |
2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.450 | |
2cdu | FAD | NADH oxidase | / | 0.450 | |
2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.450 | |
2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.450 | |
2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
3a0i | AJI | Glucokinase | 2.7.1.2 | 0.450 | |
3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.450 | |
3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.450 | |
3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
3uku | C69 | Actin-related protein 3 | / | 0.450 | |
3vt9 | YI4 | Vitamin D3 receptor | / | 0.450 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
4pyt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.450 | |
4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.450 | |
5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.450 | |
1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.449 | |
1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
1loo | GTP | Adenylosuccinate synthetase isozyme 1 | / | 0.449 | |
1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.449 | |
1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.449 | |
1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.449 | |
1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.449 | |
2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.449 | |
2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.449 | |
2gcq | DOI | Adenylosuccinate synthetase | / | 0.449 | |
2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.449 | |
2upj | U02 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.449 | |
3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.449 | |
3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.449 | |
3nbp | JGZ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.449 | |
3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
3p3z | P3Z | Putative cytochrome P450 | / | 0.449 | |
3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
3tw6 | ADP | Pyruvate carboxylase | / | 0.449 | |
3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.449 | |
4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.449 | |
4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
4gyi | ADP | Uncharacterized protein | / | 0.449 | |
4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.449 | |
4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.449 | |
4i09 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.449 | |
4ipe | ANP | TNF receptor-associated protein 1 | / | 0.449 | |
4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.449 | |
4k42 | ADP | Actin, alpha skeletal muscle | / | 0.449 | |
4q0a | 4OA | Vitamin D3 receptor A | / | 0.449 | |
4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.449 | |
1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.448 | |
1db1 | VDX | Vitamin D3 receptor | / | 0.448 | |
1hw5 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.448 | |
1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.448 | |
1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.448 | |
2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.448 | |
2j8z | NAP | Quinone oxidoreductase PIG3 | 1 | 0.448 | |
2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.448 | |
2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
3cgc | COA | Coenzyme A disulfide reductase | / | 0.448 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.448 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.448 | |
3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.448 | |
3ict | FAD | Coenzyme A disulfide reductase | / | 0.448 | |
3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.448 | |
4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.448 | |
4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.448 | |
4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.448 | |
4l17 | DNQ | Glutamate receptor 2 | / | 0.448 | |
4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.448 | |
4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.448 | |
4o7u | THF | Thymidylate synthase | / | 0.448 | |
4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.448 | |
4zhx | C1V | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | / | 0.448 | |
4zhx | C1V | 5'-AMP-activated protein kinase subunit beta-1 | / | 0.448 | |
5fm7 | ADP | RuvB-like helicase | / | 0.448 | |
3uzc | T4E | Adenosine receptor A2a | / | 0.448 | |
1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.447 | |
1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.447 | |
1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
1lp6 | C5P | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.447 | |
1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
1t1s | CBQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.447 | |
1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.447 | |
2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.447 | |
2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.447 | |
3h0s | B38 | Acetyl-CoA carboxylase | / | 0.447 | |
3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.447 | |
3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
3lmg | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.447 | |
3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.447 | |
3u4l | ATP | Actin, cytoplasmic 1 | / | 0.447 | |
3v01 | 3V0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.447 | |
4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
4iui | 1GQ | Estrogen receptor | / | 0.447 | |
4kwh | NAP | Reductase homolog | / | 0.447 | |
4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.447 | |
4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
1ppj | SMA | Cytochrome b | / | 0.446 | |
1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.446 | |
2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.446 | |
2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.446 | |
2w1h | L0F | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
3efl | 706 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
3mn6 | ATP | Actin-5C | / | 0.446 | |
3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
4aox | FAD | Steroid monooxygenase | / | 0.446 | |
4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.446 | |
4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.446 | |
4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
4j36 | 1HR | Kynurenine 3-monooxygenase | / | 0.446 | |
4j4v | SVR | Nucleocapsid protein | / | 0.446 | |
4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.446 | |
4ly9 | 1YY | Glucokinase regulatory protein | / | 0.446 | |
5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.446 | |
5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
1hpo | UNI | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.445 | |
1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
1ot7 | IU5 | Bile acid receptor | / | 0.445 | |
2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.445 | |
2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.445 | |
2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
3d45 | GDP | Poly(A)-specific ribonuclease PARN | 3.1.13.4 | 0.445 | |
3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
3gkj | HC3 | Niemann-Pick C1 protein | / | 0.445 | |
3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.445 | |
3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
3vi2 | HMZ | Orotidine 5'-monophosphate decarboxylase | / | 0.445 | |
3w0g | W07 | Vitamin D3 receptor | / | 0.445 | |
4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.445 | |
4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
4d58 | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.445 | |
4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.445 | |
4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.445 | |
4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
4k77 | 1Q4 | Tyrosine-protein kinase JAK1 | / | 0.445 | |
4l8u | 9AZ | Serum albumin | / | 0.445 | |
4mgk | CMP | Rap guanine nucleotide exchange factor 4 | / | 0.445 | |
4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
4pd6 | URI | Nucleoside permease | / | 0.445 | |
4q5h | ANP | Protein kinase OspG | 2.7 | 0.445 | |
5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
5kje | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.445 | |
3rfm | CFF | Adenosine receptor A2a | / | 0.445 | |
1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.444 | |
1ivq | 0PX | Gag-Pol polyprotein | / | 0.444 | |
1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
1tu3 | GNP | Ras-related protein Rab-5A | / | 0.444 | |
1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.444 | |
1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
2a41 | ATP | Actin, alpha skeletal muscle | / | 0.444 | |
2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
2fhy | A37 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.444 | |
2hs2 | 017 | Protease | / | 0.444 | |
2pg8 | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.444 | |
3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
3dmj | GWE | Pol protein | / | 0.444 | |
3dtw | A96 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.444 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.444 | |
3lsi | FAD | Pyranose 2-oxidase | / | 0.444 | |
3qa2 | XNA | Ketohexokinase | / | 0.444 | |
3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.444 | |
4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.444 | |
4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
4inb | 1F6 | Gag protein | / | 0.444 | |
4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
4n9i | PCG | Catabolite expression activator | / | 0.444 | |
4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.444 | |
4o71 | CPB | Bromodomain-containing protein 4 | / | 0.444 | |
4y95 | 746 | Tyrosine-protein kinase | / | 0.444 | |
5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
5itz | LOC | Tubulin beta-2B chain | / | 0.444 | |
6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.444 | |
1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
1dkf | BMS | Retinoic acid receptor alpha | / | 0.443 | |
1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.443 | |
2giv | ACO | Histone acetyltransferase KAT8 | / | 0.443 | |
2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
2wtj | WTJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.443 | |
3u9d | ATP | Actin, alpha skeletal muscle | / | 0.443 | |
3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.443 | |
4ehz | JAK | Tyrosine-protein kinase JAK1 | / | 0.443 | |
4eop | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.443 | |
4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.443 | |
4ktc | 1X3 | Genome polyprotein | 3.4.21.98 | 0.443 | |
4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.443 | |
5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.443 | |
5hid | B1E | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
1cx4 | CMP | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.442 | |
1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
1gjr | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
1ie8 | KH1 | Vitamin D3 receptor | / | 0.442 | |
1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
1u54 | ACP | Activated CDC42 kinase 1 | / | 0.442 | |
2b9w | FAD | Putative aminooxidase | / | 0.442 | |
2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.442 | |
2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.442 | |
2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.442 | |
2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.442 | |
2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.442 | |
2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
2q70 | DC8 | Estrogen receptor | / | 0.442 | |
2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.442 | |
3sz0 | FAD | Sulfide-quinone reductase | / | 0.442 | |
3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
4ia7 | BIV | Vitamin D3 receptor A | / | 0.442 | |
4iwy | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.442 | |
4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
4oae | CLM | Uncharacterized protein | / | 0.442 | |
4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
1fxs | NAP | GDP-L-fucose synthase | / | 0.441 | |
1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
1sn0 | T44 | Transthyretin | / | 0.441 | |
1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.441 | |
2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.441 | |
2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.441 | |
2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
2rhg | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
2vtp | LZ9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.441 | |
3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.441 | |
3ffk | ATP | Actin, alpha skeletal muscle | / | 0.441 | |
3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.441 | |
3ict | ADP | Coenzyme A disulfide reductase | / | 0.441 | |
3in6 | FMN | Uncharacterized protein | / | 0.441 | |
3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.441 | |
3n83 | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.441 | |
3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.441 | |
3zux | TCH | Transporter | / | 0.441 | |
4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
4brx | KGW | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
4hnc | 0UT | Mandelate racemase | / | 0.441 | |
4hzf | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.441 | |
4ite | TEY | Vitamin D3 receptor | / | 0.441 | |
4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
5ikq | JMS | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
6upj | NIU | Gag-Pol polyprotein | / | 0.441 | |
3qak | UKA | Adenosine receptor A2a | / | 0.441 | |
1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
1idb | 0DO | Gag-Pol polyprotein | / | 0.440 | |
1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.440 | |
1ot7 | CHC | Bile acid receptor | / | 0.440 | |
1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.440 | |
1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.440 | |
2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
2tct | CTC | Tetracycline repressor protein class D | / | 0.440 | |
2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2wpx | ACO | Orf14 | / | 0.440 | |
2xgo | ZKD | Uncharacterized protein | / | 0.440 | |
2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
2zgz | GNP | Plasmid segregation protein ParM | / | 0.440 | |
3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
3enk | UPG | UDP-glucose 4-epimerase | / | 0.440 | |
3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.440 | |
3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.440 | |
3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.440 | |
3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
3op5 | REB | Serine/threonine-protein kinase VRK1 | 2.7.11.1 | 0.440 | |
3p9t | TCL | Repressor | / | 0.440 | |
3q92 | XNB | Ketohexokinase | / | 0.440 | |
3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3r8p | Z46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.440 | |
3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.440 | |
3uwl | FOZ | Thymidylate synthase | / | 0.440 | |
3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
3w0i | O11 | Vitamin D3 receptor | / | 0.440 | |
3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
4bdg | P3J | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.440 | |
4dta | ADN | APH(2'')-Id | / | 0.440 | |
4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
4hjf | C2E | GGDEF family protein | / | 0.440 | |
4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
4jnq | FDA | Thioredoxin reductase | / | 0.440 | |
4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.440 | |
4mcc | 21X | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.440 | |
4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.440 | |
4prv | ADP | DNA gyrase subunit B | / | 0.440 | |
4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.440 | |
4rqz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.440 | |
4uyf | 73B | Bromodomain-containing protein 2 | / | 0.440 | |
4wud | ANP | DNA gyrase subunit B | / | 0.440 | |
4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.440 | |
4z43 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.440 | |
5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.440 |