scPDB - Distribution of Cavity Similarity values of 3svp entry / Site 2

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	1.000
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.780
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.765
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.723
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.696
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.678
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.676
4k5d	1Q6	Nitric oxide synthase, brain	1.14.13.39	0.676
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.673
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.673
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.666
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.652
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.650
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.642
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.637
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.635
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.632
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.630
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.621
3b3p	JI7	Nitric oxide synthase, brain	1.14.13.39	0.615
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.615
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.606
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.605
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.605
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.605
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.603
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.602
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.602
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.602
1p6j	DP9	Nitric oxide synthase, brain	1.14.13.39	0.601
3rqk	X2C	Nitric oxide synthase, brain	1.14.13.39	0.601
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.599
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.597
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.596
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.595
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.595
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.593
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.589
3n5v	XFH	Nitric oxide synthase, brain	1.14.13.39	0.581
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.577
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.577
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.570
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.569
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.568
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.566
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.566
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.565
3uft	HW7	Nitric oxide synthase, brain	1.14.13.39	0.565
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.556
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.553
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.553
3ufp	H4W	Nitric oxide synthase, brain	1.14.13.39	0.553
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.552
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.552
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.548
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.548
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.545
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.544
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.542
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.541
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.538
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.538
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.538
3n5y	H4B	Nitric oxide synthase, brain	1.14.13.39	0.536
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.535
1p6k	H4B	Nitric oxide synthase, brain	1.14.13.39	0.534
1rs6	DP2	Nitric oxide synthase, brain	1.14.13.39	0.531
4jsj	QJ7	Nitric oxide synthase, brain	1.14.13.39	0.530
4fw0	H4B	Nitric oxide synthase, brain	1.14.13.39	0.528
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.526
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.525
1zzq	DP9	Nitric oxide synthase, brain	1.14.13.39	0.523
2hx4	4HX	Nitric oxide synthase, brain	1.14.13.39	0.520
3tyl	AXW	Nitric oxide synthase, brain	1.14.13.39	0.517
1zzu	DP1	Nitric oxide synthase, brain	1.14.13.39	0.514
3b3o	H4B	Nitric oxide synthase, brain	1.14.13.39	0.512
3b3p	H4B	Nitric oxide synthase, brain	1.14.13.39	0.509
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.508
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.507
1m00	H4B	Nitric oxide synthase, brain	1.14.13.39	0.506
3nlo	JSR	Nitric oxide synthase, brain	1.14.13.39	0.505
3b3o	JI3	Nitric oxide synthase, brain	1.14.13.39	0.503
3jwu	J11	Nitric oxide synthase, brain	1.14.13.39	0.502
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.502
1zzr	DP9	Nitric oxide synthase, brain	1.14.13.39	0.499
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.497
1zzr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.493
3nlk	JSS	Nitric oxide synthase, brain	1.14.13.39	0.493
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.489
4imw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.488
3nlp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.487
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.486
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.486
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.483
3nlv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.480
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.479
3b3n	H4B	Nitric oxide synthase, brain	1.14.13.39	0.478
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.477
3jwv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.474
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.474
1p6j	H4B	Nitric oxide synthase, brain	1.14.13.39	0.473
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.472
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
3b3m	H4B	Nitric oxide synthase, brain	1.14.13.39	0.469
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.469
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.467
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.466
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.464
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.464
4jsh	Q15	Nitric oxide synthase, brain	1.14.13.39	0.459
1rs7	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
3svq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
4jsi	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
1rs6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
3nlq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
3uft	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.449
3e68	AT6	Nitric oxide synthase, inducible	1.14.13.39	0.442
3jt7	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
3n5v	H4B	Nitric oxide synthase, brain	1.14.13.39	0.441
3tyl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.441