sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3sl2	ATP	Sensor histidine kinase WalK

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3sl2	ATP	Sensor histidine kinase WalK	/	1.000
1i59	ANP	Chemotaxis protein CheA	2.7.13.3	0.472
4f4d	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.464
5c93	ACP	Two-component system histidine protein kinase	/	0.449
1i5c	ADP	Chemotaxis protein CheA	2.7.13.3	0.447
2wd8	VGF	Pteridine reductase	/	0.445
2yvw	EPU	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.443
1xdd	AAY	Integrin alpha-L	/	0.442
1vbi	NAD	Malate/L-lactate dehydrogenase family protein	/	0.441
4nvk	2NY	Peroxidase	/	0.441