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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3sheI85MAP kinase-activated protein kinase 32.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3sheI85MAP kinase-activated protein kinase 32.7.11.11.000
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.545
1g5sI17Cyclin-dependent kinase 22.7.11.220.540
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.536
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.533
1eh4IC1Casein kinase I homolog 12.7.11.10.531
4bgh3I6Cyclin-dependent kinase 22.7.11.220.531
1aq1STUCyclin-dependent kinase 22.7.11.220.530
1oitHDTCyclin-dependent kinase 22.7.11.220.525
1xjdSTUProtein kinase C theta type2.7.11.130.521
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.519
1oirHDYCyclin-dependent kinase 22.7.11.220.518
3lfnA27Cyclin-dependent kinase 22.7.11.220.518
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.517
1gih1PUCyclin-dependent kinase 22.7.11.220.516
3lfqA28Cyclin-dependent kinase 22.7.11.220.516
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.516
3rk708ZCyclin-dependent kinase 22.7.11.220.515
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.515
1gii1PUCyclin-dependent kinase 22.7.11.220.514
2btsU32Cyclin-dependent kinase 22.7.11.220.514
4fki09KCyclin-dependent kinase 22.7.11.220.513
4fkv61KCyclin-dependent kinase 22.7.11.220.513
1di8DTQCyclin-dependent kinase 22.7.11.220.512
1y91CT9Cyclin-dependent kinase 22.7.11.220.512
3nynSGVG protein-coupled receptor kinase 62.7.11.160.511
2vv9IM9Cyclin-dependent kinase 22.7.11.220.510
2x1nX1NCyclin-dependent kinase 22.7.11.220.509
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.509
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.509
4ek816KCyclin-dependent kinase 22.7.11.220.507
1h1s4SPCyclin-dependent kinase 22.7.11.220.506
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.506
4fkt48KCyclin-dependent kinase 22.7.11.220.506
1pxoCK7Cyclin-dependent kinase 22.7.11.220.504
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.504
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.503
1ke5LS1Cyclin-dependent kinase 22.7.11.220.502
2pvnP63Casein kinase II subunit alpha2.7.11.10.502
3gubGUBDeath-associated protein kinase 12.7.11.10.501
3rk507ZCyclin-dependent kinase 22.7.11.220.501
4fv6E57Mitogen-activated protein kinase 12.7.11.240.501
2uzoC62Cyclin-dependent kinase 22.7.11.220.500
4kbk1QGCasein kinase I isoform delta2.7.11.10.500
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.499
2b52D42Cyclin-dependent kinase 22.7.11.220.498
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.498
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.498
2btrU73Cyclin-dependent kinase 22.7.11.220.497
1pxlCK4Cyclin-dependent kinase 22.7.11.220.495
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.495
3rni21ZCyclin-dependent kinase 22.7.11.220.494
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.493
1w8cN69Cyclin-dependent kinase 22.7.11.220.493
3r8vZ62Cyclin-dependent kinase 22.7.11.220.493
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.492
3i60E86Mitogen-activated protein kinase 12.7.11.240.492
3s1h56ZCyclin-dependent kinase 22.7.11.220.492
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.492
4ek610KCyclin-dependent kinase 22.7.11.220.492
4fkj11KCyclin-dependent kinase 22.7.11.220.492
2w17I19Cyclin-dependent kinase 22.7.11.220.491
3qu0X40Cyclin-dependent kinase 22.7.11.220.491
3rjc06ZCyclin-dependent kinase 22.7.11.220.491
4fkg4CKCyclin-dependent kinase 22.7.11.220.491
1vjy460TGF-beta receptor type-12.7.11.300.490
1h1r6CPCyclin-dependent kinase 22.7.11.220.489
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.489
3s2pPMUCyclin-dependent kinase 22.7.11.220.489
3qqlX03Cyclin-dependent kinase 22.7.11.220.488
3r83Z14Cyclin-dependent kinase 22.7.11.220.488
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.488
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.487
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.487
2vu3LZECyclin-dependent kinase 22.7.11.220.487
2xmyCDKCyclin-dependent kinase 22.7.11.220.487
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.487
4jboWPHAurora kinase A2.7.11.10.487
2hog710Serine/threonine-protein kinase Chk12.7.11.10.486
2j9mPY8Cyclin-dependent kinase 22.7.11.220.486
3rkb12ZCyclin-dependent kinase 22.7.11.220.486
4btjADPTau-tubulin kinase 12.7.11.10.486
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.485
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.485
4dgmAGICasein kinase II subunit alpha2.7.11.10.485
4fkpLS5Cyclin-dependent kinase 22.7.11.220.485
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.485
1e1xNW1Cyclin-dependent kinase 22.7.11.220.484
1pxpCK8Cyclin-dependent kinase 22.7.11.220.484
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.484
4jajXU1Aurora kinase A2.7.11.10.484
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.483
1pxmCK5Cyclin-dependent kinase 22.7.11.220.483
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.483
2pvhP19Casein kinase II subunit alpha2.7.11.10.483
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.483
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.483
2r3lSCWCyclin-dependent kinase 22.7.11.220.482
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.482
2w06FRVCyclin-dependent kinase 22.7.11.220.482
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.482
3at4CCKCasein kinase II subunit alpha2.7.11.10.482
3be9P04Casein kinase II subunit alpha2.7.11.10.482
4fklCK2Cyclin-dependent kinase 22.7.11.220.482
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.482
5dr6SKEAurora kinase A2.7.11.10.482
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.481
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.481
3rk909ZCyclin-dependent kinase 22.7.11.220.481
1ke6LS2Cyclin-dependent kinase 22.7.11.220.480
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.480
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.480
1ke7LS3Cyclin-dependent kinase 22.7.11.220.479
2w1hL0FCyclin-dependent kinase 22.7.11.220.479
3pe2E1BCasein kinase II subunit alpha2.7.11.10.479
3r1yX76Cyclin-dependent kinase 22.7.11.220.479
4btjATPTau-tubulin kinase 12.7.11.10.479
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.479
1p2a5BNCyclin-dependent kinase 22.7.11.220.478
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.478
1w0xOLOCyclin-dependent kinase 22.7.11.220.478
2c6o4SPCyclin-dependent kinase 22.7.11.220.478
3qwjX6ACyclin-dependent kinase 22.7.11.220.478
3rm618ZCyclin-dependent kinase 22.7.11.220.478
4bgg844Activin receptor type-12.7.11.300.478
4eon1ROCyclin-dependent kinase 22.7.11.220.478
1ckpPVBCyclin-dependent kinase 22.7.11.220.477
2a0cCK9Cyclin-dependent kinase 22.7.11.220.477
2a4lRRCCyclin-dependent kinase 22.7.11.220.477
2r3jSCJCyclin-dependent kinase 22.7.11.220.477
2uznC96Cyclin-dependent kinase 22.7.11.220.477
3rak03ZCyclin-dependent kinase 22.7.11.220.477
4eok4SPCyclin-dependent kinase 22.7.11.220.477
5drdATPAurora kinase A2.7.11.10.477
1m2pHNACasein kinase II subunit alpha2.7.11.10.476
1v1k3FPCyclin-dependent kinase 22.7.11.220.476
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.476
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.476
4fks46KCyclin-dependent kinase 22.7.11.220.476
2iw94SPCyclin-dependent kinase 22.7.11.220.475
3ezvEZVCyclin-dependent kinase 22.7.11.220.475
3my5RFZCyclin-dependent kinase 22.7.11.220.475
3qtxX43Cyclin-dependent kinase 22.7.11.220.475
3qzgX67Cyclin-dependent kinase 22.7.11.220.475
5dr9SKEAurora kinase A2.7.11.10.475
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.474
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.474
2dwbANPAurora kinase A2.7.11.10.474
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.474
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.474
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.474
4anmWULCasein kinase II subunit alpha2.7.11.10.474
4bcpT3CCyclin-dependent kinase 22.7.11.220.474
4dgnLU2Casein kinase II subunit alpha2.7.11.10.474
4qmpDKISerine/threonine-protein kinase 242.7.11.10.474
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.474
5dnrATPAurora kinase A2.7.11.10.474
1ke9LS5Cyclin-dependent kinase 22.7.11.220.473
1pyePM1Cyclin-dependent kinase 22.7.11.220.473
3ddpRC8Cyclin-dependent kinase 22.7.11.220.473
3sw719KCyclin-dependent kinase 22.7.11.220.473
3uyt0CKCasein kinase I isoform delta2.7.11.10.473
3wblPDYCyclin-dependent kinase 22.7.11.220.473
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.473
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.472
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.472
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.472
2pvmP29Casein kinase II subunit alpha2.7.11.10.472
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.472
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.472
3rpo24ZCyclin-dependent kinase 22.7.11.220.472
3sw418KCyclin-dependent kinase 22.7.11.220.472
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.472
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.472
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.472
1r78FMDCyclin-dependent kinase 22.7.11.220.471
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.471
2vthLZ2Cyclin-dependent kinase 22.7.11.220.471
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.471
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.471
3gxlQIGTGF-beta receptor type-12.7.11.300.471
3hmm855TGF-beta receptor type-12.7.11.300.471
4eor4SPCyclin-dependent kinase 22.7.11.220.471
4fkw62KCyclin-dependent kinase 22.7.11.220.471
4jqeANPCasein kinase II subunit alpha2.7.11.10.471
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.471
2uzeC95Cyclin-dependent kinase 22.7.11.220.470
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.470
3ggfGVDSerine/threonine-protein kinase 26/0.470
3r8lZ30Cyclin-dependent kinase 22.7.11.220.470
2h96893Mitogen-activated protein kinase 82.7.11.240.469
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.469
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.469
3ddqRRCCyclin-dependent kinase 22.7.11.220.469
4fko20KCyclin-dependent kinase 22.7.11.220.469
1ke8LS4Cyclin-dependent kinase 22.7.11.220.468
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.468
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.468
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.468
3tnwF18Cyclin-dependent kinase 22.7.11.220.468
3zh8C58Protein kinase C iota type2.7.11.130.468
4ez30S0Cyclin-dependent kinase 22.7.11.220.468
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.468
4wsqKSAAP2-associated protein kinase 12.7.11.10.468
1e9hINRCyclin-dependent kinase 22.7.11.220.467
1fvv107Cyclin-dependent kinase 22.7.11.220.467
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.467
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.467
3rpv26ZCyclin-dependent kinase 22.7.11.220.467
3sqq99ZCyclin-dependent kinase 22.7.11.220.467
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.467
1vyzN5BCyclin-dependent kinase 22.7.11.220.466
2uzbC75Cyclin-dependent kinase 22.7.11.220.466
3r7yZ04Cyclin-dependent kinase 22.7.11.220.466
3rmf20ZCyclin-dependent kinase 22.7.11.220.466
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.466
1h0w207Cyclin-dependent kinase 22.7.11.220.465
1oguST8Cyclin-dependent kinase 22.7.11.220.465
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.465
2c5nCK8Cyclin-dependent kinase 22.7.11.220.465
2eufLQQCyclin-dependent kinase 62.7.11.220.465
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.465
2xb7GUIALK tyrosine kinase receptor2.7.10.10.465
3a62STURibosomal protein S6 kinase beta-12.7.11.10.465
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
4dgo0JWCasein kinase II subunit alpha2.7.11.10.465
1c1dNAIPhenylalanine dehydrogenase/0.464
1oiyN41Cyclin-dependent kinase 22.7.11.220.464
2iw84SPCyclin-dependent kinase 22.7.11.220.464
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.464
2x4f16XMyosin light chain kinase family member 42.7.11.10.464
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.464
3fz1B98Cyclin-dependent kinase 22.7.11.220.464
3pj8404Cyclin-dependent kinase 22.7.11.220.464
3rm719ZCyclin-dependent kinase 22.7.11.220.464
4acm7YGCyclin-dependent kinase 22.7.11.220.464
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.464
4f081RSTyrosine-protein kinase JAK2/0.464
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.464
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.464
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.463
2vttLZDCyclin-dependent kinase 22.7.11.220.463
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.463
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.463
4fkr45KCyclin-dependent kinase 22.7.11.220.463
4iwd1JCHepatocyte growth factor receptor2.7.10.10.463
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.463
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.462
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.462
2duv371Cyclin-dependent kinase 22.7.11.220.462
2qhcAB1Protease/0.462
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.462
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.462
3q9xEMOCasein kinase II subunit alpha2.7.11.10.462
3qtzX42Cyclin-dependent kinase 22.7.11.220.462
3qzhX69Cyclin-dependent kinase 22.7.11.220.462
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
4ux9ANPMitogen-activated protein kinase 82.7.11.240.462
1m2rMNYCasein kinase II subunit alpha2.7.11.10.461
1unlRRCCyclin-dependent-like kinase 52.7.11.10.461
1ykr628Cyclin-dependent kinase 22.7.11.220.461
2cchATPCyclin-dependent kinase 22.7.11.220.461
3nwq2NCGag-Pol polyprotein3.4.23.160.461
4aqc88ATyrosine-protein kinase JAK2/0.461
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.461
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.461
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.461
4i22IREEpidermal growth factor receptor2.7.10.10.461
4nifANPMitogen-activated protein kinase 12.7.11.240.461
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.460
2exmZIPCyclin-dependent kinase 22.7.11.220.460
2q631UNGag-Pol polyprotein3.4.23.160.460
2qd7065Gag-Pol polyprotein3.4.23.160.460
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.460
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.460
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.460
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.460
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.460
1oiuN76Cyclin-dependent kinase 22.7.11.220.459
1urwI1PCyclin-dependent kinase 22.7.11.220.459
1y8yCT7Cyclin-dependent kinase 22.7.11.220.459
1zys199Serine/threonine-protein kinase Chk12.7.11.10.459
2j0lANPFocal adhesion kinase 12.7.10.20.459
2j0m4STFocal adhesion kinase 12.7.10.20.459
2xngA0HAurora kinase A2.7.11.10.459
2yaaATPDeath-associated protein kinase 2/0.459
3qtrX36Cyclin-dependent kinase 22.7.11.220.459
3qtuX44Cyclin-dependent kinase 22.7.11.220.459
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.459
4e5w0NTTyrosine-protein kinase JAK1/0.459
4fx360KCyclin-dependent kinase 22.7.11.220.459
1bdlIM1Gag-Pol polyprotein3.4.23.160.458
1oi9N20Cyclin-dependent kinase 22.7.11.220.458
1om1IQACasein kinase II subunit alpha2.7.11.10.458
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.458
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.458
2vtqLZACyclin-dependent kinase 22.7.11.220.458
3iok1P6Tyrosine-protein kinase JAK2/0.458
3qxpX64Cyclin-dependent kinase 22.7.11.220.458
3r9oZ71Cyclin-dependent kinase 22.7.11.220.458
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.458
4deaNHIAurora kinase A2.7.11.10.458
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.458
4fkq42KCyclin-dependent kinase 22.7.11.220.458
4gub0Y4Casein kinase II subunit alpha2.7.11.10.458
4hge15VTyrosine-protein kinase JAK2/0.458
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.457
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.457
1zemNADXylitol dehydrogenase/0.457
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.457
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.457
4y93746Tyrosine-protein kinase/0.457
5dt3ATPAurora kinase A2.7.11.10.457
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.456
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.456
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.456
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.456
3r71X86Cyclin-dependent kinase 22.7.11.220.456
4e6d0NUTyrosine-protein kinase JAK2/0.456
5e8ySTUTGF-beta receptor type-22.7.11.300.456
1hckATPCyclin-dependent kinase 22.7.11.220.455
1hxbROCGag-Pol polyprotein3.4.23.160.455
1pjkANPCasein kinase II subunit alpha2.7.11.10.455
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.455
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.455
2xnbY8LCyclin-dependent kinase 22.7.11.220.455
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.455
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.455
3dfcANPDeath-associated protein kinase 12.7.11.10.455
3iggEFQCyclin-dependent kinase 22.7.11.220.455
3qx2X63Cyclin-dependent kinase 22.7.11.220.455
3vf80JETyrosine-protein kinase SYK2.7.10.20.455
4c02TAKActivin receptor type-12.7.11.300.455
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.455
4fv9E71Mitogen-activated protein kinase 12.7.11.240.455
4uyf73BBromodomain-containing protein 2/0.455
2b53D23Cyclin-dependent kinase 22.7.11.220.454
2fdd385Pol protein/0.454
2xikJ60Serine/threonine-protein kinase 252.7.11.10.454
2xvdAS6Ephrin type-B receptor 42.7.10.10.454
3cgfJNFMitogen-activated protein kinase 102.7.11.240.454
3qaaG04Gag-Pol polyprotein3.4.23.160.454
3r7vZ02Cyclin-dependent kinase 22.7.11.220.454
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.454
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.453
1vyw292Cyclin-dependent kinase 22.7.11.220.453
2c6tDT5Cyclin-dependent kinase 22.7.11.220.453
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.453
2z54AB1Gag-Pol polyprotein3.4.23.160.453
3ezrEZRCyclin-dependent kinase 22.7.11.220.453
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.453
3oom507Activin receptor type-12.7.11.300.453
3r28XA0Cyclin-dependent kinase 22.7.11.220.453
3r73X87Cyclin-dependent kinase 22.7.11.220.453
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.453
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.453
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.453
4dqc017Gag-Pol polyprotein/0.453
4dqh017Gag-Pol polyprotein/0.453
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.453
4h3qANPMitogen-activated protein kinase 12.7.11.240.453
4k33ACPFibroblast growth factor receptor 32.7.10.10.453
5dosATPAurora kinase A2.7.11.10.453
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.452
2c6iDT1Cyclin-dependent kinase 22.7.11.220.452
2ds11CDCyclin-dependent kinase 22.7.11.220.452
2qi0MZ3Gag-Pol polyprotein/0.452
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.452
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.452
3el4ROCGag-Pol polyprotein3.4.23.160.452
4dymIYZActivin receptor type-12.7.11.300.452
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.452
4nj32KDCyclin-dependent kinase 22.7.11.220.452
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.451
2r5q1UNGag-Pol polyprotein/0.451
2x9fX9FEphrin type-B receptor 42.7.10.10.451
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.451
2y9qANPMitogen-activated protein kinase 12.7.11.240.451
3ekqROCGag-Pol polyprotein3.4.23.160.451
3ql8X01Cyclin-dependent kinase 22.7.11.220.451
3qp0NI8Gag-Pol polyprotein3.4.23.160.451
3r1qX75Cyclin-dependent kinase 22.7.11.220.451
3r9hZ67Cyclin-dependent kinase 22.7.11.220.451
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.451
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4g170VNCasein kinase I isoform gamma-32.7.11.10.451
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.451
5dpvSKEAurora kinase A2.7.11.10.451
1jstATPCyclin-dependent kinase 22.7.11.220.450
1pxkCK3Cyclin-dependent kinase 22.7.11.220.450
1py5PY1TGF-beta receptor type-12.7.11.300.450
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.450
2xyeCXGGag-Pol polyprotein/0.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3el51UNGag-Pol polyprotein/0.450
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.450
3rvg17PTyrosine-protein kinase JAK2/0.450
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.450
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4ic7ANPMitogen-activated protein kinase 72.7.11.240.450
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.450
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.450
1gij2PUCyclin-dependent kinase 22.7.11.220.449
1u54ACPActivated CDC42 kinase 1/0.449
2avvMK1Gag-Pol polyprotein3.4.23.160.449
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.449
3bhtMFRCyclin-dependent kinase 22.7.11.220.449
3ekx1UNGag-Pol polyprotein3.4.23.160.449
3so9017Pol protein/0.449
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4bcoT6QCyclin-dependent kinase 22.7.11.220.449
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.449
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.449
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.449
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
1difA85Gag-Pol polyprotein/0.448
1hvsA77Gag-Pol polyprotein/0.448
1k1u0Q4Gag-Pol polyprotein3.4.23.160.448
2bhhRYUCyclin-dependent kinase 22.7.11.220.448
2c6lDT4Cyclin-dependent kinase 22.7.11.220.448
2fvdLIACyclin-dependent kinase 22.7.11.220.448
2r3iSCFCyclin-dependent kinase 22.7.11.220.448
2vtsLZCCyclin-dependent kinase 22.7.11.220.448
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.448
2zdt46CMitogen-activated protein kinase 102.7.11.240.448
3eb0DRKUncharacterized protein/0.448
3eyhIZATyrosine-protein kinase JAK1/0.448
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.448
3lq5SLQCyclin-dependent kinase 92.7.11.220.448
3mtfA3FActivin receptor type-12.7.11.300.448
3nduROCGag-Pol polyprotein3.4.23.160.448
3r7uX96Cyclin-dependent kinase 22.7.11.220.448
3u4uLNHCasein kinase II subunit alpha2.7.11.10.448
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.448
5dt0SKEAurora kinase A2.7.11.10.448
5e8xSTUTGF-beta receptor type-12.7.11.300.448
1sbgIM1Gag-Pol polyprotein/0.447
1yt9OISGag-Pol polyprotein/0.447
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.447
2xp2VGHALK tyrosine kinase receptor2.7.10.10.447
3c4xATPRhodopsin kinase/0.447
3ndxRITGag-Pol polyprotein3.4.23.160.447
3qqkX02Cyclin-dependent kinase 22.7.11.220.447
3r1sX73Cyclin-dependent kinase 22.7.11.220.447
3t3c017Gag-Pol polyprotein3.4.23.160.447
3vf9477Tyrosine-protein kinase SYK2.7.10.20.447
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.447
4btmF8ETau-tubulin kinase 12.7.11.10.447
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.447
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.447
4qgiROCGag-Pol polyprotein3.4.23.160.447
4tuvCPZCytochrome P450 1191.140.447
4wloNAIMalate dehydrogenase, mitochondrial1.1.1.370.447
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
2i4xKGQProtease/0.446
2ijmADPFocal adhesion kinase 12.7.10.20.446
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.446
2uzdC85Cyclin-dependent kinase 22.7.11.220.446
2vagV25Dual specificity protein kinase CLK12.7.12.10.446
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.446
3dckKVIProtease/0.446
3hzc2NCProtease/0.446
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.446
3lctADPALK tyrosine kinase receptor2.7.10.10.446
3r8pZ46Cyclin-dependent kinase 22.7.11.220.446
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.446
3zpuM8BGag-Pol polyprotein3.4.23.160.446
4a6bQG8Gag-Pol polyprotein3.4.23.160.446
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.446
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.446
1dawANPCasein kinase II subunit alpha2.7.11.10.445
1ec3MS3Gag-Pol polyprotein3.4.23.160.445
1h0vUN4Cyclin-dependent kinase 22.7.11.220.445
1hiiC20Gag-Pol polyprotein/0.445
2bpw1INGag-Pol polyprotein3.4.23.160.445
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.445
2r3kSCQCyclin-dependent kinase 22.7.11.220.445
2zb3NDPProstaglandin reductase 21.3.1.480.445
3ig7EFPCyclin-dependent kinase 22.7.11.220.445
3ndtROCGag-Pol polyprotein3.4.23.160.445
3q43D66M1 family aminopeptidase3.4.110.445
3zewSTUEphrin type-B receptor 42.7.10.10.445
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.445
4cfnJYMCyclin-dependent kinase 22.7.11.220.445
4dqb017Gag-Pol polyprotein/0.445
4eooATPCyclin-dependent kinase 22.7.11.220.445
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.445
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.445
4i3zADPCyclin-dependent kinase 22.7.11.220.445
4q1x017Gag-Pol polyprotein3.4.23.160.445
1b38ATPCyclin-dependent kinase 22.7.11.220.444
1fgc2NCGag-Pol polyprotein3.4.23.160.444
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1jld0PPGag-Pol polyprotein/0.444
1l7eNAINAD(P) transhydrogenase subunit alpha part 11.6.1.20.444
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.444
2ckeIQUDeath-associated protein kinase 2/0.444
2fxeDR7Gag-Pol polyprotein3.4.23.160.444
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.444
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.444
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.444
2pk6O33V-1 protease/0.444
2qi4MZ6Gag-Pol polyprotein/0.444
2wotZZGTGF-beta receptor type-12.7.11.300.444
3ec0GRLGag-Pol polyprotein3.4.23.470.444
3orkAGSSerine/threonine protein kinase/0.444
3ufnROCGag-Pol polyprotein/0.444
3unk0BYCyclin-dependent kinase 22.7.11.220.444
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.444
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.444
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
1bai0Q4Gag-Pro polyprotein/0.443
1finATPCyclin-dependent kinase 22.7.11.220.443
1hosPHPGag-Pol polyprotein/0.443
1hsgMK1Gag-Pol polyprotein/0.443
1jnkANPMitogen-activated protein kinase 102.7.11.240.443
1k2b0Q4Gag-Pol polyprotein3.4.23.160.443
2r3r6SCCyclin-dependent kinase 22.7.11.220.443
2uxzHI1Gag-Pol polyprotein3.4.23.160.443
2wouZZFTGF-beta receptor type-12.7.11.300.443
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.443
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.443
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.443
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.443
3jvy017Gag-Pol polyprotein3.4.23.160.443
3pwm017Gag-Pol polyprotein3.4.23.160.443
3s56ROCProtease/0.443
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.443
3vquO22Dual specificity protein kinase TTK2.7.12.10.443
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.443
4ez50RSCyclin-dependent kinase 62.7.11.220.443
4fmqANPMitogen-activated protein kinase 12.7.11.240.443
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.443
4tvbNADHomospermidine synthase2.5.1.440.443
1a8g2Z4Gag-Pol polyprotein3.4.23.160.442
1d4yTPVGag-Pol polyprotein3.4.23.160.442
1dayGNPCasein kinase II subunit alpha2.7.11.10.442
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.442
1p4fDRGDeath-associated protein kinase 12.7.11.10.442
1qmzATPCyclin-dependent kinase 22.7.11.220.442
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.442
2b55D31Cyclin-dependent kinase 22.7.11.220.442
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.442
2v7a627Tyrosine-protein kinase ABL12.7.10.20.442
3bu5ATPInsulin receptor2.7.10.10.442
3ekp478Gag-Pol polyprotein3.4.23.160.442
3em6017Gag-Pol polyprotein3.4.23.160.442
3nyg2NCGag-Pol polyprotein3.4.23.160.442
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.442
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.442
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.442
4hegG52Gag-Pol polyprotein3.4.23.160.442
1bdrIM1Gag-Pol polyprotein3.4.23.160.441
1sh9RITGag-Pol polyprotein3.4.23.160.441
1z1hHBBGag-Pol polyprotein3.4.23.160.441
1z1rHBHGag-Pol polyprotein3.4.23.160.441
2aidTHKGag-Pol polyprotein3.4.23.160.441
2c6kDT2Cyclin-dependent kinase 22.7.11.220.441
2fy4COACholine O-acetyltransferase2.3.1.60.441
2uy0HV1Gag-Pol polyprotein3.4.23.160.441
2vnaNAPProstaglandin reductase 21.3.1.480.441
3ekwDR7Gag-Pol polyprotein3.4.23.160.441
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.441
3ggxGGXGag-Pol polyprotein/0.441
3hllI45Mitogen-activated protein kinase 14/0.441
3nieANPMitogen-activated protein kinase/0.441
3nu9478Gag-Pol polyprotein3.4.23.160.441
3nxe2NCProtease/0.441
3pwrROCGag-Pol polyprotein3.4.23.160.441
3qqfX07Cyclin-dependent kinase 22.7.11.220.441
4c61LMMTyrosine-protein kinase JAK2/0.441
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.441
5e92ANPTGF-beta receptor type-22.7.11.300.441
1cc2FADCholesterol oxidase1.1.3.60.440
1ebwBEIGag-Pol polyprotein3.4.23.160.440
1u4dDBQActivated CDC42 kinase 1/0.440
2p3a3TLPol protein/0.440
2qi6MZ8Gag-Pol polyprotein/0.440
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.440
2zjwREFCasein kinase II subunit alpha2.7.11.10.440
3bvb017Gag-Pol polyprotein3.4.23.160.440
3nwxKVSGag-Pol polyprotein3.4.23.160.440
3oxw017Gag-Pol polyprotein3.4.23.160.440
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.440
4g6oE28Mitogen-activated protein kinase 12.7.11.240.440
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4i02CMPcAMP-activated global transcriptional regulator CRP/0.440
4ix6ADPUncharacterized protein/0.440
4k4p3TLGag-Pol polyprotein/0.440
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.440
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440