Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3sa0NRAMitogen-activated protein kinase 12.7.11.24

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3sa0NRAMitogen-activated protein kinase 12.7.11.241.000
4s33ANPMitogen-activated protein kinase 12.7.11.240.530
4s34ANPMitogen-activated protein kinase 12.7.11.240.499
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.494
4fv6E57Mitogen-activated protein kinase 12.7.11.240.486
4fv9E71Mitogen-activated protein kinase 12.7.11.240.471
3i60E86Mitogen-activated protein kinase 12.7.11.240.466
4gt3ATPMitogen-activated protein kinase 12.7.11.240.464
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.461
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.460
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.457
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.451
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.450
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.449
4h3qANPMitogen-activated protein kinase 12.7.11.240.448
4hge15VTyrosine-protein kinase JAK2/0.447
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.445
1qmzATPCyclin-dependent kinase 22.7.11.220.442