sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3ryp	CMP	cAMP-activated global transcriptional regulator CRP

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3ryp	CMP	cAMP-activated global transcriptional regulator CRP	/	1.000
4i0a	CMP	cAMP-activated global transcriptional regulator CRP	/	0.659
4i09	CMP	cAMP-activated global transcriptional regulator CRP	/	0.610
1i5z	CMP	cAMP-activated global transcriptional regulator CRP	/	0.609
2gzw	CMP	cAMP-activated global transcriptional regulator CRP	/	0.607
4hzf	CMP	cAMP-activated global transcriptional regulator CRP	/	0.602
3kcc	CMP	cAMP-activated global transcriptional regulator CRP	/	0.599
1i6x	CMP	cAMP-activated global transcriptional regulator CRP	/	0.550
1cgp	CMP	cAMP-activated global transcriptional regulator CRP	/	0.533
4i01	CMP	cAMP-activated global transcriptional regulator CRP	/	0.517
4ft8	CMP	cAMP-activated global transcriptional regulator CRP	/	0.472
4r8h	SP1	cAMP-activated global transcriptional regulator CRP	/	0.471
1ruo	CMP	cAMP-activated global transcriptional regulator CRP	/	0.467
1zrc	CMP	cAMP-activated global transcriptional regulator CRP	/	0.464
3rou	CMP	cAMP-activated global transcriptional regulator CRP	/	0.458
3rpq	CMP	cAMP-activated global transcriptional regulator CRP	/	0.454
1zrd	CMP	cAMP-activated global transcriptional regulator CRP	/	0.442