sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ry2 | BTN | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ry2 | BTN | Streptavidin | / | 1.000 | |
| 4gda | BTN | Streptavidin | / | 0.724 | |
| 4dne | DTB | Streptavidin | / | 0.687 | |
| 2izk | GLL | Streptavidin | / | 0.685 | |
| 1lcw | SHM | Streptavidin | / | 0.681 | |
| 1luq | BTN | Streptavidin | / | 0.676 | |
| 2rtg | BTN | Streptavidin | / | 0.674 | |
| 2rtn | IMI | Streptavidin | / | 0.670 | |
| 1df8 | BTN | Streptavidin | / | 0.665 | |
| 1sri | DMB | Streptavidin | / | 0.664 | |
| 2rtd | BTN | Streptavidin | / | 0.664 | |
| 2rtq | IMI | Streptavidin | / | 0.664 | |
| 1mk5 | BTN | Streptavidin | / | 0.663 | |
| 2rtk | GLL | Streptavidin | / | 0.660 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.657 | |
| 2rti | GLL | Streptavidin | / | 0.657 | |
| 4bx7 | B4F | Streptavidin | / | 0.657 | |
| 2rto | IMI | Streptavidin | / | 0.655 | |
| 2izh | BTN | Streptavidin | / | 0.654 | |
| 2rtf | BTN | Streptavidin | / | 0.654 | |
| 1srg | MHB | Streptavidin | / | 0.650 | |
| 2izl | IMI | Streptavidin | / | 0.650 | |
| 2izg | BTN | Streptavidin | / | 0.649 | |
| 1sre | HAB | Streptavidin | / | 0.648 | |
| 2izf | BTN | Streptavidin | / | 0.648 | |
| 2y3f | BTN | Streptavidin | / | 0.647 | |
| 1i9h | BNI | Streptavidin | / | 0.644 | |
| 1stp | BTN | Streptavidin | / | 0.642 | |
| 2rte | BTN | Streptavidin | / | 0.642 | |
| 3wyq | BTN | Streptavidin | / | 0.640 | |
| 1srh | MOB | Streptavidin | / | 0.637 | |
| 1swt | BTN | Streptavidin | / | 0.633 | |
| 2rtr | IMI | Streptavidin | / | 0.633 | |
| 3wzn | BTN | Streptavidin | / | 0.626 | |
| 1srf | MTB | Streptavidin | / | 0.622 | |
| 1avd | BTN | Avidin | / | 0.618 | |
| 2izi | BTN | Streptavidin | / | 0.615 | |
| 1rxh | BNI | Streptavidin | / | 0.614 | |
| 1lcz | BH7 | Streptavidin | / | 0.612 | |
| 2izj | BTN | Streptavidin | / | 0.609 | |
| 2rtp | IMI | Streptavidin | / | 0.599 | |
| 1srj | NAB | Streptavidin | / | 0.595 | |
| 2avi | BTN | Avidin | / | 0.595 | |
| 2c4i | BTN | Avidin | / | 0.594 | |
| 2rtm | IMI | Streptavidin | / | 0.592 | |
| 3rdq | DTB | Streptavidin | / | 0.588 | |
| 4z28 | BTN | Hoefavidin | / | 0.587 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.584 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.579 | |
| 1ndj | BTN | Streptavidin | / | 0.569 | |
| 2uyw | BTN | Avd protein | / | 0.559 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.555 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.554 | |
| 1nc9 | IMI | Streptavidin | / | 0.547 | |
| 1swp | BTQ | Streptavidin | / | 0.544 | |
| 2uz2 | BTN | Avd protein | / | 0.542 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.540 | |
| 1swn | BTN | Streptavidin | / | 0.537 | |
| 1n9m | BTN | Streptavidin | / | 0.536 | |
| 1mep | BTN | Streptavidin | / | 0.524 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.519 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.515 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.515 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.514 | |
| 3wyp | BSO | Streptavidin | / | 0.512 | |
| 1swp | BTN | Streptavidin | / | 0.511 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.510 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.508 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.504 | |
| 2rtl | IMI | Streptavidin | / | 0.503 | |
| 2zsc | BTN | Tamavidin2 | / | 0.503 | |
| 2a5c | 8DA | Avidin | / | 0.501 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.500 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.500 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.500 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.500 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.497 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.496 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.495 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.495 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.495 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.494 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.493 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.493 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.492 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.491 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.491 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 2jgs | BTN | Avidin | / | 0.490 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.490 | |
| 4bj8 | BTN | Avidin | / | 0.490 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.489 | |
| 1swd | BTN | Streptavidin | / | 0.489 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.489 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.488 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.488 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.488 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.488 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.488 | |
| 4ggz | BTN | Bll1558 protein | / | 0.488 | |
| 4hrq | AZG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.488 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.487 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.487 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.487 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.487 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.487 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.486 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.486 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.486 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.485 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.485 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.485 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.485 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.485 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.484 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.484 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.483 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.483 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.483 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.483 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.483 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.482 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.482 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.482 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.481 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.481 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.481 | |
| 3c1o | NAP | Eugenol synthase | / | 0.481 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.481 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.480 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.480 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.480 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.479 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.479 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.479 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.479 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.479 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.479 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.479 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.479 | |
| 1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.478 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1xp8 | AGS | Protein RecA | / | 0.478 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.478 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.478 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.478 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.478 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.477 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.477 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.477 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.477 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.477 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.477 | |
| 5dp2 | NAP | CurF | / | 0.477 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.476 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.476 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.476 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.476 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.476 | |
| 1fkx | PRH | Adenosine deaminase | 3.5.4.4 | 0.475 | |
| 1qjg | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.475 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.475 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.475 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.475 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.475 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.474 | |
| 1lke | DOG | Bilin-binding protein | / | 0.474 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.474 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.474 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.474 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 3eks | CY9 | Actin-5C | / | 0.474 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.474 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.473 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.473 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.473 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.473 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1kzi | THG | Thymidylate synthase | / | 0.472 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.472 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.472 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.472 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.472 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.472 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.472 | |
| 4l64 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.472 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.471 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.471 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.471 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.471 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.471 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.471 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.471 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.471 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.471 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.471 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.471 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.471 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.471 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.470 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.470 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1s36 | CEI | Obelin | / | 0.470 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.470 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.470 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.470 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.470 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.470 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3owy | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.470 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.470 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.470 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.470 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.469 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.469 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.469 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.469 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.469 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.469 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.469 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.469 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.469 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.469 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.469 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.469 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.469 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.469 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.469 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.469 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.469 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.469 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.469 | |
| 1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.468 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.468 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.468 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.468 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.468 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.468 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.468 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.467 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.467 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.467 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.467 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.467 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.467 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.467 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.467 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.467 | |
| 2npf | MOU | Elongation factor 2 | / | 0.467 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.467 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.467 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.467 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.467 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.467 | |
| 3rdo | BTN | Streptavidin | / | 0.467 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.467 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.467 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.467 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.466 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.466 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.465 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.465 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.465 | |
| 3arv | SAU | Chitinase A | / | 0.465 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.465 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.465 | |
| 3rim | TPP | Transketolase | 2.2.1.1 | 0.465 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.465 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.465 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
| 4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.465 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.464 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.464 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.464 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.464 | |
| 1wur | 8DG | GTP cyclohydrolase 1 | / | 0.464 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.464 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.464 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.464 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.464 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.464 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.464 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.464 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.464 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.464 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.464 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.463 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.463 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.463 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.463 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.463 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.463 | |
| 3up3 | XCA | aceDAF-12 | / | 0.463 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.463 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.463 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.463 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.463 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.462 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.462 | |
| 2kce | D16 | Thymidylate synthase | / | 0.462 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.462 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.462 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 3vgw | NVZ | Avidin | / | 0.462 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.462 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.461 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.461 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.461 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.461 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.461 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.461 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.461 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.461 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.461 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.461 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.461 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.461 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 4hxo | 1A6 | Bromodomain-containing protein 4 | / | 0.461 | |
| 4j0k | EGR | Tannase | / | 0.461 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.461 | |
| 4pd6 | URI | Nucleoside permease | / | 0.461 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.461 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.461 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.461 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.460 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.460 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 1u1j | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | 2.1.1.14 | 0.460 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.460 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.460 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.460 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.460 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.460 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 4dli | IRG | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.460 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.460 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.460 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 4wkb | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.460 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.460 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.459 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.459 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.459 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.459 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.459 | |
| 1szc | CNA | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.459 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.459 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.459 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.459 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.459 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.459 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.458 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1r2j | FAD | FkbI | / | 0.458 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.458 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.458 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.458 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 3up0 | D7S | aceDAF-12 | / | 0.458 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.458 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.458 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.458 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.458 | |
| 4xd1 | T3Q | Qdtf | / | 0.458 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.458 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.457 | |
| 1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.457 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.457 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.457 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.457 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.457 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.457 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.457 | |
| 2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.457 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.457 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.457 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.457 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3gb4 | D3M | DdmC | / | 0.457 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.457 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.457 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.457 | |
| 5gcn | COA | HAT A1 | / | 0.457 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.456 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1tys | TMP | Thymidylate synthase | / | 0.456 | |
| 1u22 | THG | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | 2.1.1.14 | 0.456 | |
| 1yim | CM4 | Estrogen receptor | / | 0.456 | |
| 2ada | HPR | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.456 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.456 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.456 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.456 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.456 | |
| 2pit | DHT | Androgen receptor | / | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.456 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.456 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.456 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.456 | |
| 4k5p | 1OS | M1 family aminopeptidase | 3.4.11 | 0.456 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.456 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.456 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.455 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.455 | |
| 2r5n | TPP | Transketolase 1 | / | 0.455 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.455 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.455 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.455 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.455 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.455 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.455 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.455 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.455 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.455 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.454 | |
| 1egc | CO8 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.454 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.454 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.454 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.454 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.454 | |
| 3r96 | ACO | MccE protein | / | 0.454 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.454 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.454 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.454 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.454 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.454 | |
| 5cpm | FNR | NADH:flavin oxidoreductase | / | 0.454 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.453 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1osv | CHC | Bile acid receptor | / | 0.453 | |
| 1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.453 | |
| 1u5c | BIK | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.453 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.453 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.453 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.453 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.453 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.453 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.453 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.453 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.453 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 4bqu | CLR | Japanin | / | 0.453 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.453 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.452 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.452 | |
| 1til | ATP | Anti-sigma F factor | / | 0.452 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.452 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.452 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 2j6x | FMN | Lactate oxidase | / | 0.452 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.452 | |
| 2yhu | WHF | Pteridine reductase | / | 0.452 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.452 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.452 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.452 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.452 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.452 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.452 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.452 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4kwh | NAP | Reductase homolog | / | 0.452 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.452 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.452 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.451 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.451 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.451 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.451 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.451 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.451 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.451 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.451 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.451 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.451 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.451 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.451 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 3gtc | GTC | Beta-lactamase | 3.5.2.6 | 0.451 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.451 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.451 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.451 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.451 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.451 | |
| 3zqt | TES | Androgen receptor | / | 0.451 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.451 | |
| 4h6p | FMN | Chromate reductase | / | 0.451 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.451 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.451 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.451 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.451 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.450 | |
| 1c7o | PPG | Hemolysin | / | 0.450 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.450 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.450 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.450 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.450 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.450 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.450 | |
| 2bxo | OPB | Serum albumin | / | 0.450 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.450 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.450 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.450 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2nm2 | NEU | Dihydroneopterin aldolase | / | 0.450 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.450 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.450 | |
| 3uq9 | TBN | Putative adenosine kinase | / | 0.450 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.450 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 4dij | BLF | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.450 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.450 | |
| 4gd9 | BTN | Streptavidin | / | 0.450 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.450 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.450 | |
| 4mr5 | 1K0 | Bromodomain-containing protein 2 | / | 0.450 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.450 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.450 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
| 4y3r | F06 | Endothiapepsin | 3.4.23.22 | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1e2n | RCA | Thymidine kinase | / | 0.449 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.449 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.449 | |
| 1ldq | SHM | Avidin | / | 0.449 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.449 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.449 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.449 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2y71 | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.449 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.449 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3ghh | 2NF | CD38 molecule | / | 0.449 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.449 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.449 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.449 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.449 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.449 | |
| 4kxj | P34 | Nucleoprotein | / | 0.449 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.449 | |
| 4u7w | NDP | MxaA | / | 0.449 | |
| 4ys2 | 2BA | Uncharacterized protein | / | 0.449 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.448 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.448 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1ppj | ANY | Cytochrome b | / | 0.448 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.448 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.448 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.448 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.448 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.448 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.448 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.448 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.448 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.448 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.448 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.448 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.448 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.448 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.448 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4y1b | NAP | AntE | / | 0.448 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.447 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1ddt | APU | Diphtheria toxin | / | 0.447 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.447 | |
| 1ecb | 5GP | Amidophosphoribosyltransferase | / | 0.447 | |
| 1efa | NPF | Lactose operon repressor | / | 0.447 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.447 | |
| 1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.447 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.447 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1t7f | DHT | Androgen receptor | / | 0.447 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.447 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.447 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.447 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.447 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.447 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.447 | |
| 3ldo | ANP | 78 kDa glucose-regulated protein | / | 0.447 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.447 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.447 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.447 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.447 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.447 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.447 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.447 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.447 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.447 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.446 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.446 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.446 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.446 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.446 | |
| 1s1p | NAP | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1ws1 | BB2 | Peptide deformylase 1 | / | 0.446 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.446 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.446 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.446 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4bfq | 083 | Soluble acetylcholine receptor | / | 0.446 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.446 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.446 | |
| 4g0k | 0VS | Glutathionyl-hydroquinone reductase YqjG | 1.8 | 0.446 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4rel | KMP | Glycosyltransferase | / | 0.446 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.446 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.446 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1axw | MTX | Thymidylate synthase | / | 0.445 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.445 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1lqa | NDP | Protein tas | / | 0.445 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.445 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.445 | |
| 2dy9 | ADP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2fai | 459 | Estrogen receptor | / | 0.445 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.445 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.445 | |
| 2j08 | IRF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.445 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.445 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.445 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.445 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.445 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.445 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.445 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.445 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.445 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.445 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.445 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.445 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.445 | |
| 4ijr | NDP | D-arabinose dehydrogenase [NAD(P)+] heavy chain | 1.1.1.117 | 0.445 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4n1g | CEI | Obelin | / | 0.445 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.445 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.445 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.445 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.445 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.444 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.444 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.444 | |
| 1fml | RTL | Retinol dehydratase | / | 0.444 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.444 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.444 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.444 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.444 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.444 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1tox | NAD | Diphtheria toxin | / | 0.444 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.444 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.444 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3klb | FMN | Uncharacterized protein | / | 0.444 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.444 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.444 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
| 3wd2 | A1L | Chitinase B | 3.2.1.14 | 0.444 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.444 | |
| 3zs5 | SB2 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.444 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.444 | |
| 4e5f | 0N7 | Polymerase acidic protein | / | 0.444 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.444 | |
| 4o7u | THF | Thymidylate synthase | / | 0.444 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.444 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.444 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.444 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.443 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1mdt | APU | Diphtheria toxin | / | 0.443 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.443 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1yvf | PH7 | Polyprotein | / | 0.443 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.443 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.443 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.443 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.443 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 2wbg | LGS | Beta-glucosidase A | 3.2.1.21 | 0.443 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.443 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.443 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.443 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.443 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.443 | |
| 2zf4 | PPY | Uncharacterized protein | / | 0.443 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.443 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.443 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.443 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.443 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.443 | |
| 4j0j | E35 | Tannase | / | 0.443 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.443 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.442 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.442 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 1t5b | FMN | FMN-dependent NADH-azoreductase | / | 0.442 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.442 | |
| 2e7z | MGD | Acetylene hydratase | / | 0.442 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.442 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.442 | |
| 2piw | DHT | Androgen receptor | / | 0.442 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2qpy | DHT | Androgen receptor | / | 0.442 | |
| 2r8o | T5X | Transketolase 1 | / | 0.442 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.442 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.442 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.442 | |
| 3ewd | MCF | Adenosine deaminase, putative | / | 0.442 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.442 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.442 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.442 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.442 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.442 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3od4 | 8XQ | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.442 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.442 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.442 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.442 | |
| 3v4a | PK1 | Androgen receptor | / | 0.442 | |
| 3wff | WFF | Mineralocorticoid receptor | / | 0.442 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.442 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.442 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.442 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.442 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.442 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.442 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.442 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.442 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.442 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.442 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.441 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1g28 | FMN | PHY3 | / | 0.441 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1jqi | CAA | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.441 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.441 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.441 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.441 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.441 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2fto | TMP | Thymidylate synthase | / | 0.441 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.441 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.441 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.441 | |
| 3q5p | TAC | Multidrug-efflux transporter 1 regulator | / | 0.441 | |
| 3v49 | PK0 | Androgen receptor | / | 0.441 | |
| 3vri | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.441 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.441 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.441 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.441 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4okw | 198 | Androgen receptor | / | 0.441 | |
| 4rtm | SAM | DNA adenine methylase | 2.1.1.72 | 0.441 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 5c3r | HMU | Thymine dioxygenase | / | 0.441 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.440 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.440 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.440 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.440 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.440 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.440 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.440 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.440 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.440 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.440 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.440 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.440 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.440 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.440 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.440 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.440 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.440 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.440 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.440 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3ihz | FK5 | Peptidylprolyl isomerase | / | 0.440 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.440 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3v0t | ATR | Perakine reductase | 1.1.1.317 | 0.440 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.440 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.440 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.440 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.440 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.440 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.440 | |
| 4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4y0k | NAP | AntE | / | 0.440 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.440 |