Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rs5GNPGTPase HRas

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rs5GNPGTPase HRas/1.000
3oivGNPGTPase HRas/0.848
3lbnGNPGTPase HRas/0.700
3rs7GNPGTPase HRas/0.699
3v4fGNPGTPase HRas/0.676
3oiuGNPGTPase HRas/0.637
5b2zGNPGTPase HRas/0.630
3i3sGNPGTPase HRas/0.623
4dlwGNPGTPase HRas/0.617
4dlxGNPGTPase HRas/0.598
3kucGDPRas-related protein Rap-1A/0.577
2rgcGNPGTPase HRas/0.576
4dlvGNPGTPase HRas/0.571
4nyjGNPGTPase HRas/0.569
2rgeGNPGTPase HRas/0.566
4nyiGNPGTPase HRas/0.560
4dlzGNPGTPase HRas/0.556
1zc4GNPRas-related protein Ral-A/0.553
1zc3GNPRas-related protein Ral-A/0.548
5dhaGNPGTP-binding nuclear protein Ran/0.534
4kvgGTPRas-related protein Rap-1A/0.531
3ddcGNPGTPase HRas/0.526
1xtrGNPGTP-binding protein Rheb/0.523
2rgbGNPGTPase HRas/0.519
3rabGNPRas-related protein Rab-3A/0.516
4mitGTPRho-related protein racC/0.516
3tsoGNPRas-related protein Rab-25/0.510
1ibrGNPGTP-binding nuclear protein Ran/0.509
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.509
4o25GTPGTP-binding protein Rheb/0.509
4lhwGNPRas-related protein Rab-8A/0.508
4dxaGSPRas-related protein Rap-1b/0.506
1xtsGTPGTP-binding protein Rheb/0.505
1m7bGTPRho-related GTP-binding protein RhoE/0.504
1kmqGNPTransforming protein RhoA/0.503
1cxzGSPTransforming protein RhoA/0.502
3rs0GNPGTPase HRas/0.502
3bc1GNPRas-related protein Rab-27A/0.501
1uadGNPRas-related protein Ral-A/0.500
4dsuGDPGTPase KRas/0.500
5jljGNPGTP-binding nuclear protein Ran/0.498
3ea5GDPGTP-binding nuclear protein Ran/0.495
1g17GNPRas-related protein SEC4/0.487
3e5hGNPRas-related protein Rab-28/0.483
4dltGNPGTPase HRas/0.481
5hpyGDPTransforming protein RhoA/0.481
3kz1GSPTransforming protein RhoA/0.480
3nbzGTPGTP-binding nuclear protein Ran/0.477
1s1cGNPTransforming protein RhoA/0.476
1ow3GDPTransforming protein RhoA/0.475
1yhnGTPRas-related protein Rab-7a/0.475
3rslGNPGTPase HRas/0.475
4qxaGTPRas-related protein Rab-9A/0.472
3l8yGNPGTPase HRas/0.469
3tnfGNPRas-related protein Rab-8A/0.469
1oixGDPRas-related protein Rab-11A/0.467
2c5lGTPGTPase HRas/0.467
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.467
1yzqGNPRas-related protein Rab-6A/0.466
2zetGTPRas-related protein Rab-27B/0.466
1zbdGTPRas-related protein Rab-3A/0.465
3eg5GNPCell division control protein 42 homolog/0.464
4dlsGNPGTPase HRas/0.464
3oiwGNPGTPase HRas/0.463
1t91GTPRas-related protein Rab-7a/0.462
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.460
4rkfGNPRas-related protein Rab-3/0.458
2cl6CAGGTPase HRas/0.457
3kkoGNPRas-related protein M-Ras/0.457
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.455
3w3zGTPGTP-binding nuclear protein Ran/0.453
2gcpGSPRho-related GTP-binding protein RhoC/0.452
4js0GNPCell division control protein 42 homolog/0.451
2gilGTPRas-related protein Rab-6A/0.450
4dsoGSPGTPase KRas/0.448
2clsGTPRho-related GTP-binding protein Rho6/0.447
3a58GNPGTP-binding protein RHO1/0.447
3a6pGTPGTP-binding nuclear protein Ran/0.446
3k8yGNPGTPase HRas/0.445
2ffqGSPRas-related protein Rab-6B/0.444
1vg8GNPRas-related protein Rab-7a/0.442
2fe4GDPRas-related protein Rab-6B/0.442
3bbpGTPRas-related protein Rab-6A/0.441
4dsnGCPGTPase KRas/0.440
4g0nGNPGTPase HRas/0.440