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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rpo24ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rpo24ZCyclin-dependent kinase 22.7.11.221.000
3r73X87Cyclin-dependent kinase 22.7.11.220.570
3rm618ZCyclin-dependent kinase 22.7.11.220.555
3lfnA27Cyclin-dependent kinase 22.7.11.220.551
3r1yX76Cyclin-dependent kinase 22.7.11.220.542
3r7yZ04Cyclin-dependent kinase 22.7.11.220.541
1w8cN69Cyclin-dependent kinase 22.7.11.220.539
3r71X86Cyclin-dependent kinase 22.7.11.220.529
3qwjX6ACyclin-dependent kinase 22.7.11.220.526
3qqfX07Cyclin-dependent kinase 22.7.11.220.525
3r8lZ30Cyclin-dependent kinase 22.7.11.220.521
3rk909ZCyclin-dependent kinase 22.7.11.220.521
3qzgX67Cyclin-dependent kinase 22.7.11.220.520
3qqlX03Cyclin-dependent kinase 22.7.11.220.518
1ykr628Cyclin-dependent kinase 22.7.11.220.517
3r8vZ62Cyclin-dependent kinase 22.7.11.220.517
3qx2X63Cyclin-dependent kinase 22.7.11.220.513
3rk708ZCyclin-dependent kinase 22.7.11.220.513
3iggEFQCyclin-dependent kinase 22.7.11.220.512
2a0cCK9Cyclin-dependent kinase 22.7.11.220.510
3r83Z14Cyclin-dependent kinase 22.7.11.220.508
4fki09KCyclin-dependent kinase 22.7.11.220.508
4fkj11KCyclin-dependent kinase 22.7.11.220.508
2btrU73Cyclin-dependent kinase 22.7.11.220.507
4ek610KCyclin-dependent kinase 22.7.11.220.505
2b52D42Cyclin-dependent kinase 22.7.11.220.503
3r1sX73Cyclin-dependent kinase 22.7.11.220.500
2a4lRRCCyclin-dependent kinase 22.7.11.220.499
3lfqA28Cyclin-dependent kinase 22.7.11.220.496
2exmZIPCyclin-dependent kinase 22.7.11.220.495
3qu0X40Cyclin-dependent kinase 22.7.11.220.495
3rni21ZCyclin-dependent kinase 22.7.11.220.493
1pxmCK5Cyclin-dependent kinase 22.7.11.220.492
3rkb12ZCyclin-dependent kinase 22.7.11.220.492
3r7uX96Cyclin-dependent kinase 22.7.11.220.487
1y91CT9Cyclin-dependent kinase 22.7.11.220.484
3rpv26ZCyclin-dependent kinase 22.7.11.220.484
2uzoC62Cyclin-dependent kinase 22.7.11.220.483
4fkg4CKCyclin-dependent kinase 22.7.11.220.483
1pxlCK4Cyclin-dependent kinase 22.7.11.220.482
3r8pZ46Cyclin-dependent kinase 22.7.11.220.482
1ke7LS3Cyclin-dependent kinase 22.7.11.220.481
3qx4X4BCyclin-dependent kinase 22.7.11.220.481
1ke5LS1Cyclin-dependent kinase 22.7.11.220.480
3rahO1ZCyclin-dependent kinase 22.7.11.220.480
3sqq99ZCyclin-dependent kinase 22.7.11.220.479
1pxoCK7Cyclin-dependent kinase 22.7.11.220.478
3qtuX44Cyclin-dependent kinase 22.7.11.220.478
4kd11QKCyclin-dependent kinase 22.7.11.220.478
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.477
3s1h56ZCyclin-dependent kinase 22.7.11.220.476
3qzhX69Cyclin-dependent kinase 22.7.11.220.474
3rk507ZCyclin-dependent kinase 22.7.11.220.474
2vtsLZCCyclin-dependent kinase 22.7.11.220.472
2c6o4SPCyclin-dependent kinase 22.7.11.220.471
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.467
4fklCK2Cyclin-dependent kinase 22.7.11.220.465
1oitHDTCyclin-dependent kinase 22.7.11.220.464
3r28XA0Cyclin-dependent kinase 22.7.11.220.464
3rak03ZCyclin-dependent kinase 22.7.11.220.464
3qruX19Cyclin-dependent kinase 22.7.11.220.462
1hckATPCyclin-dependent kinase 22.7.11.220.461
4ek816KCyclin-dependent kinase 22.7.11.220.461
1b38ATPCyclin-dependent kinase 22.7.11.220.460
1vyzN5BCyclin-dependent kinase 22.7.11.220.460
3rm719ZCyclin-dependent kinase 22.7.11.220.460
1h0w207Cyclin-dependent kinase 22.7.11.220.459
2xmyCDKCyclin-dependent kinase 22.7.11.220.459
1g5sI17Cyclin-dependent kinase 22.7.11.220.457
1ke6LS2Cyclin-dependent kinase 22.7.11.220.457
3qxoX65Cyclin-dependent kinase 22.7.11.220.457
3s0o50ZCyclin-dependent kinase 22.7.11.220.457
3qtxX43Cyclin-dependent kinase 22.7.11.220.456
4fkpLS5Cyclin-dependent kinase 22.7.11.220.456
3r6xX84Cyclin-dependent kinase 22.7.11.220.453
3r9hZ67Cyclin-dependent kinase 22.7.11.220.453
1ckpPVBCyclin-dependent kinase 22.7.11.220.452
1e1xNW1Cyclin-dependent kinase 22.7.11.220.452
2btsU32Cyclin-dependent kinase 22.7.11.220.452
2vttLZDCyclin-dependent kinase 22.7.11.220.452
2vu3LZECyclin-dependent kinase 22.7.11.220.452
5aniES4Cyclin-dependent kinase 22.7.11.220.452
1v1k3FPCyclin-dependent kinase 22.7.11.220.451
1w0xOLOCyclin-dependent kinase 22.7.11.220.451
3sw418KCyclin-dependent kinase 22.7.11.220.449
1h1s4SPCyclin-dependent kinase 22.7.11.220.448
3ql8X01Cyclin-dependent kinase 22.7.11.220.448
1oirHDYCyclin-dependent kinase 22.7.11.220.447
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.446
4bgh3I6Cyclin-dependent kinase 22.7.11.220.446
4fkq42KCyclin-dependent kinase 22.7.11.220.446
2b53D23Cyclin-dependent kinase 22.7.11.220.445
2w1hL0FCyclin-dependent kinase 22.7.11.220.444
3ig7EFPCyclin-dependent kinase 22.7.11.220.444
1gih1PUCyclin-dependent kinase 22.7.11.220.443
3py0SU9Cyclin-dependent kinase 22.7.11.220.443
3rjc06ZCyclin-dependent kinase 22.7.11.220.442
3rmf20ZCyclin-dependent kinase 22.7.11.220.441
2c6lDT4Cyclin-dependent kinase 22.7.11.220.440
2w06FRVCyclin-dependent kinase 22.7.11.220.440