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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rm719ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rm719ZCyclin-dependent kinase 22.7.11.221.000
3qxoX65Cyclin-dependent kinase 22.7.11.220.698
3r7vZ02Cyclin-dependent kinase 22.7.11.220.659
3qx2X63Cyclin-dependent kinase 22.7.11.220.645
3raiX85Cyclin-dependent kinase 22.7.11.220.645
3r6xX84Cyclin-dependent kinase 22.7.11.220.614
2btrU73Cyclin-dependent kinase 22.7.11.220.605
3r73X87Cyclin-dependent kinase 22.7.11.220.579
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.574
3qtxX43Cyclin-dependent kinase 22.7.11.220.574
3qzgX67Cyclin-dependent kinase 22.7.11.220.571
4ek610KCyclin-dependent kinase 22.7.11.220.571
3qqfX07Cyclin-dependent kinase 22.7.11.220.570
4fki09KCyclin-dependent kinase 22.7.11.220.568
3r8lZ30Cyclin-dependent kinase 22.7.11.220.567
3qzhX69Cyclin-dependent kinase 22.7.11.220.560
3qwjX6ACyclin-dependent kinase 22.7.11.220.558
3sqq99ZCyclin-dependent kinase 22.7.11.220.557
2c6o4SPCyclin-dependent kinase 22.7.11.220.556
3s2pPMUCyclin-dependent kinase 22.7.11.220.556
3iggEFQCyclin-dependent kinase 22.7.11.220.554
3rk909ZCyclin-dependent kinase 22.7.11.220.554
3r9hZ67Cyclin-dependent kinase 22.7.11.220.552
2uzoC62Cyclin-dependent kinase 22.7.11.220.551
3r7yZ04Cyclin-dependent kinase 22.7.11.220.551
4ez30S0Cyclin-dependent kinase 22.7.11.220.548
1pxmCK5Cyclin-dependent kinase 22.7.11.220.546
3r1sX73Cyclin-dependent kinase 22.7.11.220.546
3r1yX76Cyclin-dependent kinase 22.7.11.220.545
3qtqX35Cyclin-dependent kinase 22.7.11.220.543
3r8vZ62Cyclin-dependent kinase 22.7.11.220.542
4fkq42KCyclin-dependent kinase 22.7.11.220.542
3fz1B98Cyclin-dependent kinase 22.7.11.220.540
3lfqA28Cyclin-dependent kinase 22.7.11.220.540
4kd11QKCyclin-dependent kinase 22.7.11.220.538
4fkpLS5Cyclin-dependent kinase 22.7.11.220.536
3lfsA07Cyclin-dependent kinase 22.7.11.220.535
2btsU32Cyclin-dependent kinase 22.7.11.220.534
1w8cN69Cyclin-dependent kinase 22.7.11.220.533
4fkg4CKCyclin-dependent kinase 22.7.11.220.532
3r7eX88Cyclin-dependent kinase 22.7.11.220.531
1ke6LS2Cyclin-dependent kinase 22.7.11.220.530
1ke5LS1Cyclin-dependent kinase 22.7.11.220.529
3rjc06ZCyclin-dependent kinase 22.7.11.220.529
2a4lRRCCyclin-dependent kinase 22.7.11.220.528
2c69CT8Cyclin-dependent kinase 22.7.11.220.528
1v1k3FPCyclin-dependent kinase 22.7.11.220.527
3r28XA0Cyclin-dependent kinase 22.7.11.220.527
1h0w207Cyclin-dependent kinase 22.7.11.220.526
1oiqHDUCyclin-dependent kinase 22.7.11.220.526
1p2a5BNCyclin-dependent kinase 22.7.11.220.526
2c6iDT1Cyclin-dependent kinase 22.7.11.220.526
1ckpPVBCyclin-dependent kinase 22.7.11.220.524
1gih1PUCyclin-dependent kinase 22.7.11.220.524
3ezvEZVCyclin-dependent kinase 22.7.11.220.524
1ke7LS3Cyclin-dependent kinase 22.7.11.220.523
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.521
2w06FRVCyclin-dependent kinase 22.7.11.220.521
3rm618ZCyclin-dependent kinase 22.7.11.220.521
4lyn1YGCyclin-dependent kinase 22.7.11.220.521
1ykr628Cyclin-dependent kinase 22.7.11.220.520
2uznC96Cyclin-dependent kinase 22.7.11.220.520
2vthLZ2Cyclin-dependent kinase 22.7.11.220.520
3roy22ZCyclin-dependent kinase 22.7.11.220.520
3rahO1ZCyclin-dependent kinase 22.7.11.220.519
2r3iSCFCyclin-dependent kinase 22.7.11.220.518
3qtzX42Cyclin-dependent kinase 22.7.11.220.518
3r7uX96Cyclin-dependent kinase 22.7.11.220.518
3rk708ZCyclin-dependent kinase 22.7.11.220.518
3s0o50ZCyclin-dependent kinase 22.7.11.220.517
4fkt48KCyclin-dependent kinase 22.7.11.220.517
3rni21ZCyclin-dependent kinase 22.7.11.220.516
1vyzN5BCyclin-dependent kinase 22.7.11.220.515
2r3r6SCCyclin-dependent kinase 22.7.11.220.515
2r64740Cyclin-dependent kinase 22.7.11.220.515
2r3p3SCCyclin-dependent kinase 22.7.11.220.514
3qqkX02Cyclin-dependent kinase 22.7.11.220.512
2r3lSCWCyclin-dependent kinase 22.7.11.220.511
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.511
3r1qX75Cyclin-dependent kinase 22.7.11.220.511
2a0cCK9Cyclin-dependent kinase 22.7.11.220.510
2fvdLIACyclin-dependent kinase 22.7.11.220.509
3qtuX44Cyclin-dependent kinase 22.7.11.220.509
1fvt106Cyclin-dependent kinase 22.7.11.220.508
1g5sI17Cyclin-dependent kinase 22.7.11.220.508
2r3o2SCCyclin-dependent kinase 22.7.11.220.507
3ezrEZRCyclin-dependent kinase 22.7.11.220.507
3r8uZ31Cyclin-dependent kinase 22.7.11.220.506
3rk507ZCyclin-dependent kinase 22.7.11.220.506
3wblPDYCyclin-dependent kinase 22.7.11.220.506
1pxoCK7Cyclin-dependent kinase 22.7.11.220.505
3ddpRC8Cyclin-dependent kinase 22.7.11.220.505
3qqhX0ACyclin-dependent kinase 22.7.11.220.505
3qwkX62Cyclin-dependent kinase 22.7.11.220.505
3r7iX9ICyclin-dependent kinase 22.7.11.220.505
4fkr45KCyclin-dependent kinase 22.7.11.220.502
3ig7EFPCyclin-dependent kinase 22.7.11.220.501
3qqlX03Cyclin-dependent kinase 22.7.11.220.501
3r9dX6BCyclin-dependent kinase 22.7.11.220.501
2vtsLZCCyclin-dependent kinase 22.7.11.220.499
2xmyCDKCyclin-dependent kinase 22.7.11.220.499
3rpv26ZCyclin-dependent kinase 22.7.11.220.498
2b55D31Cyclin-dependent kinase 22.7.11.220.497
2r3kSCQCyclin-dependent kinase 22.7.11.220.497
4ek816KCyclin-dependent kinase 22.7.11.220.496
3r9nZ68Cyclin-dependent kinase 22.7.11.220.495
4bgh3I6Cyclin-dependent kinase 22.7.11.220.494
1ke8LS4Cyclin-dependent kinase 22.7.11.220.493
1ke9LS5Cyclin-dependent kinase 22.7.11.220.493
1w0xOLOCyclin-dependent kinase 22.7.11.220.493
2r3mSCXCyclin-dependent kinase 22.7.11.220.493
3r71X86Cyclin-dependent kinase 22.7.11.220.492
4fkj11KCyclin-dependent kinase 22.7.11.220.492
2r3gSC9Cyclin-dependent kinase 22.7.11.220.490
2w1hL0FCyclin-dependent kinase 22.7.11.220.490
3ti1B49Cyclin-dependent kinase 22.7.11.220.489
3r8pZ46Cyclin-dependent kinase 22.7.11.220.488
1urwI1PCyclin-dependent kinase 22.7.11.220.485
2c6mDT5Cyclin-dependent kinase 22.7.11.220.485
2r3fSC8Cyclin-dependent kinase 22.7.11.220.485
2vu3LZECyclin-dependent kinase 22.7.11.220.485
2w05FRTCyclin-dependent kinase 22.7.11.220.484
4acm7YGCyclin-dependent kinase 22.7.11.220.484
1oguST8Cyclin-dependent kinase 22.7.11.220.483
2b52D42Cyclin-dependent kinase 22.7.11.220.483
3ddqRRCCyclin-dependent kinase 22.7.11.220.483
3qruX19Cyclin-dependent kinase 22.7.11.220.483
1b39ATPCyclin-dependent kinase 22.7.11.220.482
1e1xNW1Cyclin-dependent kinase 22.7.11.220.482
3sw418KCyclin-dependent kinase 22.7.11.220.482
3s00Z60Cyclin-dependent kinase 22.7.11.220.481
2c4g514Cyclin-dependent kinase 22.7.11.220.480
3ral04ZCyclin-dependent kinase 22.7.11.220.480
1vyw292Cyclin-dependent kinase 22.7.11.220.479
2wpa889Cyclin-dependent kinase 22.7.11.220.479
1gii1PUCyclin-dependent kinase 22.7.11.220.478
4eor4SPCyclin-dependent kinase 22.7.11.220.478
1pyePM1Cyclin-dependent kinase 22.7.11.220.477
3s1h56ZCyclin-dependent kinase 22.7.11.220.477
1r78FMDCyclin-dependent kinase 22.7.11.220.476
4nj32KDCyclin-dependent kinase 22.7.11.220.476
1h0vUN4Cyclin-dependent kinase 22.7.11.220.475
1h1s4SPCyclin-dependent kinase 22.7.11.220.473
1oirHDYCyclin-dependent kinase 22.7.11.220.473
1h1r6CPCyclin-dependent kinase 22.7.11.220.471
2b54D05Cyclin-dependent kinase 22.7.11.220.471
2bhhRYUCyclin-dependent kinase 22.7.11.220.471
2iw94SPCyclin-dependent kinase 22.7.11.220.471
4bcmT7ZCyclin-dependent kinase 22.7.11.220.471
4fx360KCyclin-dependent kinase 22.7.11.220.471
5aniES4Cyclin-dependent kinase 22.7.11.220.471
3tiz3TICyclin-dependent kinase 22.7.11.220.470
3rak03ZCyclin-dependent kinase 22.7.11.220.469
4bcpT3CCyclin-dependent kinase 22.7.11.220.469
1hckATPCyclin-dependent kinase 22.7.11.220.468
3qxpX64Cyclin-dependent kinase 22.7.11.220.468
1di8DTQCyclin-dependent kinase 22.7.11.220.467
1y91CT9Cyclin-dependent kinase 22.7.11.220.467
3pj8404Cyclin-dependent kinase 22.7.11.220.467
3unk0BYCyclin-dependent kinase 22.7.11.220.467
2iw84SPCyclin-dependent kinase 22.7.11.220.466
4fkv61KCyclin-dependent kinase 22.7.11.220.465
2c6kDT2Cyclin-dependent kinase 22.7.11.220.464
3qtsX46Cyclin-dependent kinase 22.7.11.220.464
3qzfX66Cyclin-dependent kinase 22.7.11.220.464
3pxyJWSCyclin-dependent kinase 22.7.11.220.463
1pxkCK3Cyclin-dependent kinase 22.7.11.220.462
2duv371Cyclin-dependent kinase 22.7.11.220.462
3rpy27ZCyclin-dependent kinase 22.7.11.220.462
1oi9N20Cyclin-dependent kinase 22.7.11.220.461
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.460
1pxpCK8Cyclin-dependent kinase 22.7.11.220.457
2c5yMTWCyclin-dependent kinase 22.7.11.220.457
3unj0BXCyclin-dependent kinase 22.7.11.220.457
3ql8X01Cyclin-dependent kinase 22.7.11.220.455
3qtrX36Cyclin-dependent kinase 22.7.11.220.455
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.454
3my5RFZCyclin-dependent kinase 22.7.11.220.454
4fko20KCyclin-dependent kinase 22.7.11.220.454
4eon1ROCyclin-dependent kinase 22.7.11.220.453
1unlRRCCyclin-dependent-like kinase 52.7.11.10.452
2w17I19Cyclin-dependent kinase 22.7.11.220.452
3qu0X40Cyclin-dependent kinase 22.7.11.220.452
2r3q5SCCyclin-dependent kinase 22.7.11.220.451
3sw719KCyclin-dependent kinase 22.7.11.220.451
1gz8MBPCyclin-dependent kinase 22.7.11.220.449
4eomATPCyclin-dependent kinase 22.7.11.220.449
2uzlC94Cyclin-dependent kinase 22.7.11.220.448
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.446
3rpr25ZCyclin-dependent kinase 22.7.11.220.446
2b53D23Cyclin-dependent kinase 22.7.11.220.445
2i40BLZCyclin-dependent kinase 22.7.11.220.445
1dm2HMDCyclin-dependent kinase 22.7.11.220.444
4eos1ROCyclin-dependent kinase 22.7.11.220.444
1oiyN41Cyclin-dependent kinase 22.7.11.220.443
1e9hINRCyclin-dependent kinase 22.7.11.220.442
1gij2PUCyclin-dependent kinase 22.7.11.220.442
1finATPCyclin-dependent kinase 22.7.11.220.441
1oiuN76Cyclin-dependent kinase 22.7.11.220.441
2vttLZDCyclin-dependent kinase 22.7.11.220.441
3sheI85MAP kinase-activated protein kinase 32.7.11.10.441