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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rm618ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rm618ZCyclin-dependent kinase 22.7.11.221.000
3r7uX96Cyclin-dependent kinase 22.7.11.220.554
3r9dX6BCyclin-dependent kinase 22.7.11.220.544
3lfnA27Cyclin-dependent kinase 22.7.11.220.543
3rpo24ZCyclin-dependent kinase 22.7.11.220.542
3qwjX6ACyclin-dependent kinase 22.7.11.220.541
3rjc06ZCyclin-dependent kinase 22.7.11.220.535
2b52D42Cyclin-dependent kinase 22.7.11.220.533
3r83Z14Cyclin-dependent kinase 22.7.11.220.530
3rk909ZCyclin-dependent kinase 22.7.11.220.530
2fvdLIACyclin-dependent kinase 22.7.11.220.519
3r8pZ46Cyclin-dependent kinase 22.7.11.220.518
3r7yZ04Cyclin-dependent kinase 22.7.11.220.517
4ek816KCyclin-dependent kinase 22.7.11.220.517
3qtuX44Cyclin-dependent kinase 22.7.11.220.506
3rpv26ZCyclin-dependent kinase 22.7.11.220.506
3qrtX14Cyclin-dependent kinase 22.7.11.220.503
3qu0X40Cyclin-dependent kinase 22.7.11.220.503
2vu3LZECyclin-dependent kinase 22.7.11.220.502
3qqlX03Cyclin-dependent kinase 22.7.11.220.502
3r1yX76Cyclin-dependent kinase 22.7.11.220.502
1w8cN69Cyclin-dependent kinase 22.7.11.220.501
3sqq99ZCyclin-dependent kinase 22.7.11.220.498
3qzgX67Cyclin-dependent kinase 22.7.11.220.497
3rak03ZCyclin-dependent kinase 22.7.11.220.496
4fki09KCyclin-dependent kinase 22.7.11.220.495
1ykr628Cyclin-dependent kinase 22.7.11.220.494
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.494
2c6o4SPCyclin-dependent kinase 22.7.11.220.489
4nj32KDCyclin-dependent kinase 22.7.11.220.489
1g5sI17Cyclin-dependent kinase 22.7.11.220.487
3r8vZ62Cyclin-dependent kinase 22.7.11.220.487
3r1sX73Cyclin-dependent kinase 22.7.11.220.485
4fkj11KCyclin-dependent kinase 22.7.11.220.485
3lfqA28Cyclin-dependent kinase 22.7.11.220.481
3qtxX43Cyclin-dependent kinase 22.7.11.220.481
3r71X86Cyclin-dependent kinase 22.7.11.220.480
3qtrX36Cyclin-dependent kinase 22.7.11.220.479
3r7eX88Cyclin-dependent kinase 22.7.11.220.478
3r7vZ02Cyclin-dependent kinase 22.7.11.220.478
2a0cCK9Cyclin-dependent kinase 22.7.11.220.477
2btrU73Cyclin-dependent kinase 22.7.11.220.473
1pxoCK7Cyclin-dependent kinase 22.7.11.220.471
4acm7YGCyclin-dependent kinase 22.7.11.220.471
3qxoX65Cyclin-dependent kinase 22.7.11.220.470
1pxmCK5Cyclin-dependent kinase 22.7.11.220.468
3qqkX02Cyclin-dependent kinase 22.7.11.220.468
2w1hL0FCyclin-dependent kinase 22.7.11.220.467
3ezvEZVCyclin-dependent kinase 22.7.11.220.466
3rahO1ZCyclin-dependent kinase 22.7.11.220.466
3rni21ZCyclin-dependent kinase 22.7.11.220.466
4ek610KCyclin-dependent kinase 22.7.11.220.465
1ckpPVBCyclin-dependent kinase 22.7.11.220.463
3r73X87Cyclin-dependent kinase 22.7.11.220.463
3r8lZ30Cyclin-dependent kinase 22.7.11.220.463
1ke5LS1Cyclin-dependent kinase 22.7.11.220.460
1ke7LS3Cyclin-dependent kinase 22.7.11.220.460
3iggEFQCyclin-dependent kinase 22.7.11.220.460
3r9hZ67Cyclin-dependent kinase 22.7.11.220.460
4fkpLS5Cyclin-dependent kinase 22.7.11.220.460
3qziX72Cyclin-dependent kinase 22.7.11.220.459
3s1h56ZCyclin-dependent kinase 22.7.11.220.459
2r3mSCXCyclin-dependent kinase 22.7.11.220.457
2btsU32Cyclin-dependent kinase 22.7.11.220.456
3qruX19Cyclin-dependent kinase 22.7.11.220.456
2r3kSCQCyclin-dependent kinase 22.7.11.220.455
3ezrEZRCyclin-dependent kinase 22.7.11.220.455
3pj8404Cyclin-dependent kinase 22.7.11.220.455
1oitHDTCyclin-dependent kinase 22.7.11.220.454
1vyw292Cyclin-dependent kinase 22.7.11.220.454
2a4lRRCCyclin-dependent kinase 22.7.11.220.453
2r3p3SCCyclin-dependent kinase 22.7.11.220.453
2exmZIPCyclin-dependent kinase 22.7.11.220.452
3fz1B98Cyclin-dependent kinase 22.7.11.220.452
3rkb12ZCyclin-dependent kinase 22.7.11.220.452
3rm719ZCyclin-dependent kinase 22.7.11.220.452
4fkv61KCyclin-dependent kinase 22.7.11.220.452
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.450
2xmyCDKCyclin-dependent kinase 22.7.11.220.450
3ig7EFPCyclin-dependent kinase 22.7.11.220.450
3qzhX69Cyclin-dependent kinase 22.7.11.220.450
4fkr45KCyclin-dependent kinase 22.7.11.220.450
3qx2X63Cyclin-dependent kinase 22.7.11.220.449
3qxpX64Cyclin-dependent kinase 22.7.11.220.449
3rk708ZCyclin-dependent kinase 22.7.11.220.449
4fklCK2Cyclin-dependent kinase 22.7.11.220.448
1y91CT9Cyclin-dependent kinase 22.7.11.220.446
2vttLZDCyclin-dependent kinase 22.7.11.220.446
3r6xX84Cyclin-dependent kinase 22.7.11.220.446
4kd11QKCyclin-dependent kinase 22.7.11.220.446
1p2a5BNCyclin-dependent kinase 22.7.11.220.444
2b55D31Cyclin-dependent kinase 22.7.11.220.444
2r3lSCWCyclin-dependent kinase 22.7.11.220.444
3r28XA0Cyclin-dependent kinase 22.7.11.220.444
1aq1STUCyclin-dependent kinase 22.7.11.220.443
1h0vUN4Cyclin-dependent kinase 22.7.11.220.443
2vthLZ2Cyclin-dependent kinase 22.7.11.220.443
4bgh3I6Cyclin-dependent kinase 22.7.11.220.443
2uzoC62Cyclin-dependent kinase 22.7.11.220.442
2r3gSC9Cyclin-dependent kinase 22.7.11.220.441
2vtsLZCCyclin-dependent kinase 22.7.11.220.441
4fks46KCyclin-dependent kinase 22.7.11.220.440
4fkt48KCyclin-dependent kinase 22.7.11.220.440