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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rjc06ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rjc06ZCyclin-dependent kinase 22.7.11.221.000
3r9dX6BCyclin-dependent kinase 22.7.11.220.636
2b52D42Cyclin-dependent kinase 22.7.11.220.615
3qu0X40Cyclin-dependent kinase 22.7.11.220.598
3rpv26ZCyclin-dependent kinase 22.7.11.220.587
3s1h56ZCyclin-dependent kinase 22.7.11.220.584
3qtrX36Cyclin-dependent kinase 22.7.11.220.576
3lfnA27Cyclin-dependent kinase 22.7.11.220.573
3rak03ZCyclin-dependent kinase 22.7.11.220.572
3rm618ZCyclin-dependent kinase 22.7.11.220.570
3qzgX67Cyclin-dependent kinase 22.7.11.220.564
3rni21ZCyclin-dependent kinase 22.7.11.220.560
2r3lSCWCyclin-dependent kinase 22.7.11.220.553
2btrU73Cyclin-dependent kinase 22.7.11.220.550
2r3kSCQCyclin-dependent kinase 22.7.11.220.550
3qtuX44Cyclin-dependent kinase 22.7.11.220.550
4acm7YGCyclin-dependent kinase 22.7.11.220.550
1pxmCK5Cyclin-dependent kinase 22.7.11.220.549
3rk909ZCyclin-dependent kinase 22.7.11.220.546
4fkv61KCyclin-dependent kinase 22.7.11.220.545
1g5sI17Cyclin-dependent kinase 22.7.11.220.544
3r8vZ62Cyclin-dependent kinase 22.7.11.220.543
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.542
4fkq42KCyclin-dependent kinase 22.7.11.220.540
4fkpLS5Cyclin-dependent kinase 22.7.11.220.539
3r8lZ30Cyclin-dependent kinase 22.7.11.220.538
2c6o4SPCyclin-dependent kinase 22.7.11.220.537
3rk708ZCyclin-dependent kinase 22.7.11.220.537
2w1hL0FCyclin-dependent kinase 22.7.11.220.534
3qtzX42Cyclin-dependent kinase 22.7.11.220.533
3pj8404Cyclin-dependent kinase 22.7.11.220.532
3qtxX43Cyclin-dependent kinase 22.7.11.220.532
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.530
3ezvEZVCyclin-dependent kinase 22.7.11.220.529
3sqq99ZCyclin-dependent kinase 22.7.11.220.529
2a0cCK9Cyclin-dependent kinase 22.7.11.220.528
1oitHDTCyclin-dependent kinase 22.7.11.220.526
1y91CT9Cyclin-dependent kinase 22.7.11.220.524
4bgh3I6Cyclin-dependent kinase 22.7.11.220.523
3rmf20ZCyclin-dependent kinase 22.7.11.220.521
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.520
1ke5LS1Cyclin-dependent kinase 22.7.11.220.519
2vv9IM9Cyclin-dependent kinase 22.7.11.220.519
2w06FRVCyclin-dependent kinase 22.7.11.220.518
4fkt48KCyclin-dependent kinase 22.7.11.220.518
1w0xOLOCyclin-dependent kinase 22.7.11.220.517
3rkb12ZCyclin-dependent kinase 22.7.11.220.517
1ke9LS5Cyclin-dependent kinase 22.7.11.220.516
2w17I19Cyclin-dependent kinase 22.7.11.220.516
1gih1PUCyclin-dependent kinase 22.7.11.220.515
3iggEFQCyclin-dependent kinase 22.7.11.220.515
3qxpX64Cyclin-dependent kinase 22.7.11.220.514
3ral04ZCyclin-dependent kinase 22.7.11.220.513
1ckpPVBCyclin-dependent kinase 22.7.11.220.512
3r7yZ04Cyclin-dependent kinase 22.7.11.220.512
4ek610KCyclin-dependent kinase 22.7.11.220.512
1pxoCK7Cyclin-dependent kinase 22.7.11.220.511
1v1k3FPCyclin-dependent kinase 22.7.11.220.511
4ek816KCyclin-dependent kinase 22.7.11.220.508
4fkg4CKCyclin-dependent kinase 22.7.11.220.508
3r1yX76Cyclin-dependent kinase 22.7.11.220.507
4fkj11KCyclin-dependent kinase 22.7.11.220.507
2xmyCDKCyclin-dependent kinase 22.7.11.220.506
3r83Z14Cyclin-dependent kinase 22.7.11.220.506
2btsU32Cyclin-dependent kinase 22.7.11.220.504
3qwjX6ACyclin-dependent kinase 22.7.11.220.504
2r3jSCJCyclin-dependent kinase 22.7.11.220.503
2b55D31Cyclin-dependent kinase 22.7.11.220.502
3qxoX65Cyclin-dependent kinase 22.7.11.220.502
4fkr45KCyclin-dependent kinase 22.7.11.220.502
3qqhX0ACyclin-dependent kinase 22.7.11.220.500
2vtsLZCCyclin-dependent kinase 22.7.11.220.498
3s0o50ZCyclin-dependent kinase 22.7.11.220.498
2uznC96Cyclin-dependent kinase 22.7.11.220.496
1urwI1PCyclin-dependent kinase 22.7.11.220.493
3ig7EFPCyclin-dependent kinase 22.7.11.220.493
3qqkX02Cyclin-dependent kinase 22.7.11.220.493
3r9hZ67Cyclin-dependent kinase 22.7.11.220.493
3rm719ZCyclin-dependent kinase 22.7.11.220.491
1p2a5BNCyclin-dependent kinase 22.7.11.220.490
3rpo24ZCyclin-dependent kinase 22.7.11.220.490
1ke6LS2Cyclin-dependent kinase 22.7.11.220.489
3rk507ZCyclin-dependent kinase 22.7.11.220.489
3s2pPMUCyclin-dependent kinase 22.7.11.220.488
1gii1PUCyclin-dependent kinase 22.7.11.220.487
1h1r6CPCyclin-dependent kinase 22.7.11.220.487
1ke7LS3Cyclin-dependent kinase 22.7.11.220.487
4ez30S0Cyclin-dependent kinase 22.7.11.220.487
3unk0BYCyclin-dependent kinase 22.7.11.220.486
4fki09KCyclin-dependent kinase 22.7.11.220.486
4fks46KCyclin-dependent kinase 22.7.11.220.486
2iw84SPCyclin-dependent kinase 22.7.11.220.484
2uzoC62Cyclin-dependent kinase 22.7.11.220.484
4fkw62KCyclin-dependent kinase 22.7.11.220.484
1h1s4SPCyclin-dependent kinase 22.7.11.220.479
2a4lRRCCyclin-dependent kinase 22.7.11.220.479
2vthLZ2Cyclin-dependent kinase 22.7.11.220.477
3lfqA28Cyclin-dependent kinase 22.7.11.220.476
3wblPDYCyclin-dependent kinase 22.7.11.220.476
1pxlCK4Cyclin-dependent kinase 22.7.11.220.475
2r3p3SCCyclin-dependent kinase 22.7.11.220.475
3py0SU9Cyclin-dependent kinase 22.7.11.220.475
3ti1B49Cyclin-dependent kinase 22.7.11.220.475
3unj0BXCyclin-dependent kinase 22.7.11.220.475
2vttLZDCyclin-dependent kinase 22.7.11.220.474
1oguST8Cyclin-dependent kinase 22.7.11.220.472
3r71X86Cyclin-dependent kinase 22.7.11.220.472
1w8cN69Cyclin-dependent kinase 22.7.11.220.471
2fvdLIACyclin-dependent kinase 22.7.11.220.471
3sw418KCyclin-dependent kinase 22.7.11.220.471
4eon1ROCyclin-dependent kinase 22.7.11.220.471
1vyzN5BCyclin-dependent kinase 22.7.11.220.470
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.470
2c6iDT1Cyclin-dependent kinase 22.7.11.220.469
3qqlX03Cyclin-dependent kinase 22.7.11.220.469
3r9oZ71Cyclin-dependent kinase 22.7.11.220.469
3r7vZ02Cyclin-dependent kinase 22.7.11.220.468
4fx360KCyclin-dependent kinase 22.7.11.220.468
1h0vUN4Cyclin-dependent kinase 22.7.11.220.467
3fz1B98Cyclin-dependent kinase 22.7.11.220.467
1aq1STUCyclin-dependent kinase 22.7.11.220.466
3r6xX84Cyclin-dependent kinase 22.7.11.220.466
1ykr628Cyclin-dependent kinase 22.7.11.220.465
1b38ATPCyclin-dependent kinase 22.7.11.220.464
2vu3LZECyclin-dependent kinase 22.7.11.220.462
2duv371Cyclin-dependent kinase 22.7.11.220.461
1vyw292Cyclin-dependent kinase 22.7.11.220.460
3qzhX69Cyclin-dependent kinase 22.7.11.220.460
3lfsA07Cyclin-dependent kinase 22.7.11.220.459
1oirHDYCyclin-dependent kinase 22.7.11.220.458
2exmZIPCyclin-dependent kinase 22.7.11.220.458
2iw94SPCyclin-dependent kinase 22.7.11.220.458
3ddpRC8Cyclin-dependent kinase 22.7.11.220.458
3rahO1ZCyclin-dependent kinase 22.7.11.220.457
3roy22ZCyclin-dependent kinase 22.7.11.220.457
4fko20KCyclin-dependent kinase 22.7.11.220.457
1e9hINRCyclin-dependent kinase 22.7.11.220.456
1pyePM1Cyclin-dependent kinase 22.7.11.220.456
3r8pZ46Cyclin-dependent kinase 22.7.11.220.456
1qmzATPCyclin-dependent kinase 22.7.11.220.454
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.454
3r7uX96Cyclin-dependent kinase 22.7.11.220.454
4nj32KDCyclin-dependent kinase 22.7.11.220.454
1fvt106Cyclin-dependent kinase 22.7.11.220.453
1r78FMDCyclin-dependent kinase 22.7.11.220.452
4bcpT3CCyclin-dependent kinase 22.7.11.220.451
1dm2HMDCyclin-dependent kinase 22.7.11.220.450
1oi9N20Cyclin-dependent kinase 22.7.11.220.449
3rpy27ZCyclin-dependent kinase 22.7.11.220.449
3pxyJWSCyclin-dependent kinase 22.7.11.220.448
4eor4SPCyclin-dependent kinase 22.7.11.220.448
1e1xNW1Cyclin-dependent kinase 22.7.11.220.447
2r3mSCXCyclin-dependent kinase 22.7.11.220.447
3r1sX73Cyclin-dependent kinase 22.7.11.220.447
2c6kDT2Cyclin-dependent kinase 22.7.11.220.446
3ddqRRCCyclin-dependent kinase 22.7.11.220.446
3r73X87Cyclin-dependent kinase 22.7.11.220.443
1oiyN41Cyclin-dependent kinase 22.7.11.220.442