sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rhq | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3rhq | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 1.000 | |
| 4gnz | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.672 | |
| 3rhj | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.549 | |
| 4go2 | TAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.503 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.483 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.446 | |
| 3rhr | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.441 |