sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rdq | DTB | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3rdq | DTB | Streptavidin | / | 1.000 | |
| 2izh | BTN | Streptavidin | / | 0.545 | |
| 1srg | MHB | Streptavidin | / | 0.522 | |
| 2rtf | BTN | Streptavidin | / | 0.521 | |
| 2rtg | BTN | Streptavidin | / | 0.521 | |
| 1srj | NAB | Streptavidin | / | 0.519 | |
| 4bx7 | B4F | Streptavidin | / | 0.519 | |
| 3rdo | BTN | Streptavidin | / | 0.514 | |
| 1srf | MTB | Streptavidin | / | 0.513 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.513 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.511 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.511 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.509 | |
| 1sre | HAB | Streptavidin | / | 0.507 | |
| 4dne | DTB | Streptavidin | / | 0.506 | |
| 2rto | IMI | Streptavidin | / | 0.504 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.504 | |
| 1mk5 | BTN | Streptavidin | / | 0.503 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.501 | |
| 5a3b | APR | SIR2 family protein | / | 0.500 | |
| 1srh | MOB | Streptavidin | / | 0.498 | |
| 4gda | BTN | Streptavidin | / | 0.497 | |
| 1lcw | SHM | Streptavidin | / | 0.495 | |
| 2rtd | BTN | Streptavidin | / | 0.494 | |
| 2rti | GLL | Streptavidin | / | 0.494 | |
| 3ry2 | BTN | Streptavidin | / | 0.494 | |
| 1sri | DMB | Streptavidin | / | 0.492 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.491 | |
| 2izf | BTN | Streptavidin | / | 0.490 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.489 | |
| 1rxh | BNI | Streptavidin | / | 0.488 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.488 | |
| 2rtr | IMI | Streptavidin | / | 0.488 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.487 | |
| 2rtp | IMI | Streptavidin | / | 0.487 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.487 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.486 | |
| 2rte | BTN | Streptavidin | / | 0.485 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.484 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.484 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.484 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.483 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.483 | |
| 2izg | BTN | Streptavidin | / | 0.483 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1stp | BTN | Streptavidin | / | 0.482 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.482 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.482 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.482 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.481 | |
| 2izk | GLL | Streptavidin | / | 0.481 | |
| 1i9h | BNI | Streptavidin | / | 0.480 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.480 | |
| 2izl | IMI | Streptavidin | / | 0.479 | |
| 2rtn | IMI | Streptavidin | / | 0.479 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.477 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.477 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.476 | |
| 2rtq | IMI | Streptavidin | / | 0.476 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.476 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.475 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.475 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.475 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 2y3f | BTN | Streptavidin | / | 0.474 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.474 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.474 | |
| 4e2d | FMN | Dehydrogenase | / | 0.474 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.473 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.473 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.473 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.473 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.473 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.472 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.472 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.472 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.472 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.472 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.472 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.472 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.471 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.471 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.471 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.470 | |
| 3mje | NDP | AmphB | / | 0.470 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.470 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.469 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.469 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.469 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.469 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.469 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.469 | |
| 1lcz | BH7 | Streptavidin | / | 0.468 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.468 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.468 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.467 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.467 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.467 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.466 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 2rtk | GLL | Streptavidin | / | 0.466 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.466 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.465 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.465 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.465 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.465 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.465 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.464 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.464 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.464 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.464 | |
| 3zkb | ANP | DNA gyrase subunit B | / | 0.464 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.463 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.463 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.463 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.463 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.463 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.463 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.463 | |
| 3wyq | BTN | Streptavidin | / | 0.462 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.462 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.462 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.462 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.462 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.461 | |
| 1osv | CHC | Bile acid receptor | / | 0.461 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.461 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
| 4e2b | FMN | Dehydrogenase | / | 0.461 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 1df8 | BTN | Streptavidin | / | 0.460 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.460 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.460 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.460 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.460 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.460 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.460 | |
| 1fml | RTL | Retinol dehydratase | / | 0.459 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.459 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.459 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.459 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.459 | |
| 3e8x | NAP | BH1520 protein | / | 0.459 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.459 | |
| 4ajb | TAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.459 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.459 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.459 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 4z28 | BTN | Hoefavidin | / | 0.459 | |
| 1eio | GCH | Gastrotropin | / | 0.458 | |
| 1ihy | APR | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.458 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.458 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.458 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.458 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.458 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 1luq | BTN | Streptavidin | / | 0.457 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.457 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.457 | |
| 2kce | D16 | Thymidylate synthase | / | 0.457 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.457 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.457 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.457 | |
| 3v3v | MYU | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.457 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.457 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 4l4x | NDP | AmphI | / | 0.457 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.457 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.457 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.456 | |
| 1gae | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.456 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.456 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.456 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 3wag | TYD | Glycosyltransferase | / | 0.456 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4hia | FMN | LOV protein | / | 0.456 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.456 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.456 | |
| 4ymk | ST9 | Acyl-CoA desaturase 1 | / | 0.456 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.456 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.455 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.455 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.455 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.455 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.455 | |
| 3zkd | ANP | DNA gyrase subunit B | / | 0.455 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.455 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.454 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.454 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.454 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.454 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4hus | VIR | Virginiamycin A acetyltransferase | 2.3.1 | 0.454 | |
| 4hxy | NDP | Plm1 | / | 0.454 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.454 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.454 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.453 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.453 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.453 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.453 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.453 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.453 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 2izj | BTN | Streptavidin | / | 0.453 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.453 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.453 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.453 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.453 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 2avi | BTN | Avidin | / | 0.452 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2pmn | K51 | Protein kinase 7 | / | 0.452 | |
| 2rtm | IMI | Streptavidin | / | 0.452 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.452 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3upf | 0BU | Polyprotein | / | 0.452 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.452 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.452 | |
| 1efa | NPF | Lactose operon repressor | / | 0.451 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.451 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.451 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.451 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.451 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.451 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.451 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.451 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.451 | |
| 2xvv | 9DN | Serum albumin | / | 0.451 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.451 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.451 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.451 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.451 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.451 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.451 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.451 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.451 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.451 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.450 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.450 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.450 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.450 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.450 | |
| 3p9t | TCL | Repressor | / | 0.450 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 4e8w | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.450 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.450 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.450 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.449 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.449 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.449 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.449 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.449 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.449 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.449 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.448 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.448 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.448 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.448 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2zrj | AGS | Protein RecA | / | 0.448 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.448 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.448 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.448 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.448 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.448 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.448 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1s3g | AP5 | Adenylate kinase | / | 0.447 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.447 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.447 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 2ejz | SAH | Diphthine synthase | / | 0.447 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.447 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.447 | |
| 2qir | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.447 | |
| 3arv | SAU | Chitinase A | / | 0.447 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.447 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.447 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.447 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.447 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.447 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.446 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.446 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.446 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.446 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.446 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.446 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.446 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.446 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.446 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.445 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.445 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.445 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.445 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.445 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.445 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.445 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.445 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.445 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.445 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.445 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.445 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.445 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.445 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.445 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 4pd6 | URI | Nucleoside permease | / | 0.445 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.444 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.444 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.444 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2z4z | SC0 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.444 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3eku | CY9 | Actin-5C | / | 0.444 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.444 | |
| 3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.444 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.444 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.444 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 4hhd | FMN | Phototropin-1 | 2.7.11.1 | 0.444 | |
| 4hj6 | FMN | LOV protein | / | 0.444 | |
| 4hl1 | ZZ7 | Metallo-beta-lactamase type 2 | / | 0.444 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.444 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.444 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.444 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.443 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.443 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.443 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.443 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.443 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.443 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.443 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.443 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.443 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.443 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.443 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3v2u | ATP | Protein GAL3 | / | 0.443 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.443 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.443 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1u0y | PA7 | Endoplasmin | / | 0.442 | |
| 1vbn | YSA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.442 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.442 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.442 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.442 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.442 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.442 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.442 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.442 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.442 | |
| 1fdi | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.441 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.441 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.441 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.441 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 2e20 | B4P | Propionate kinase | / | 0.441 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.441 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.441 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.441 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.441 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.441 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.441 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.441 | |
| 4fox | UMP | Thymidylate synthase ThyA | / | 0.441 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.441 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.441 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.441 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.440 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1zdw | FLV | Prenyltransferase | / | 0.440 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.440 | |
| 2izi | BTN | Streptavidin | / | 0.440 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.440 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.440 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zxu | DST | tRNA dimethylallyltransferase | 2.5.1.75 | 0.440 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.440 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.440 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.440 | |
| 3kdt | 7HA | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.440 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.440 | |
| 4kq2 | U5P | Glycogen [starch] synthase isoform 2 | 2.4.1.11 | 0.440 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.440 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.440 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.440 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.440 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.440 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 |