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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rak03ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rak03ZCyclin-dependent kinase 22.7.11.221.000
3s1h56ZCyclin-dependent kinase 22.7.11.220.769
3qxpX64Cyclin-dependent kinase 22.7.11.220.589
3ral04ZCyclin-dependent kinase 22.7.11.220.543
2fvdLIACyclin-dependent kinase 22.7.11.220.520
3rmf20ZCyclin-dependent kinase 22.7.11.220.517
2vu3LZECyclin-dependent kinase 22.7.11.220.512
2w17I19Cyclin-dependent kinase 22.7.11.220.507
3sw418KCyclin-dependent kinase 22.7.11.220.502
2vv9IM9Cyclin-dependent kinase 22.7.11.220.497
3rkb12ZCyclin-dependent kinase 22.7.11.220.496
2w05FRTCyclin-dependent kinase 22.7.11.220.492
3ezvEZVCyclin-dependent kinase 22.7.11.220.489
1fvv107Cyclin-dependent kinase 22.7.11.220.488
1y91CT9Cyclin-dependent kinase 22.7.11.220.488
3qtxX43Cyclin-dependent kinase 22.7.11.220.487
4bgh3I6Cyclin-dependent kinase 22.7.11.220.477
1gii1PUCyclin-dependent kinase 22.7.11.220.476
3rpv26ZCyclin-dependent kinase 22.7.11.220.476
3sqq99ZCyclin-dependent kinase 22.7.11.220.476
3r9dX6BCyclin-dependent kinase 22.7.11.220.475
3rpy27ZCyclin-dependent kinase 22.7.11.220.470
4fkv61KCyclin-dependent kinase 22.7.11.220.470
2j9mPY8Cyclin-dependent kinase 22.7.11.220.465
3rjc06ZCyclin-dependent kinase 22.7.11.220.464
3sw719KCyclin-dependent kinase 22.7.11.220.464
3qtrX36Cyclin-dependent kinase 22.7.11.220.460
2uznC96Cyclin-dependent kinase 22.7.11.220.458
2vttLZDCyclin-dependent kinase 22.7.11.220.457
2btsU32Cyclin-dependent kinase 22.7.11.220.456
1pxoCK7Cyclin-dependent kinase 22.7.11.220.455
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.452
3qu0X40Cyclin-dependent kinase 22.7.11.220.450
1pxmCK5Cyclin-dependent kinase 22.7.11.220.449
2b52D42Cyclin-dependent kinase 22.7.11.220.449
2xmyCDKCyclin-dependent kinase 22.7.11.220.448
4fkr45KCyclin-dependent kinase 22.7.11.220.447
3at4CCKCasein kinase II subunit alpha2.7.11.10.446
3rk708ZCyclin-dependent kinase 22.7.11.220.446
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.445
4acm7YGCyclin-dependent kinase 22.7.11.220.445
1w0xOLOCyclin-dependent kinase 22.7.11.220.444
3r8lZ30Cyclin-dependent kinase 22.7.11.220.444
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
4aqc88ATyrosine-protein kinase JAK2/0.442
1qmzATPCyclin-dependent kinase 22.7.11.220.441
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.440
3axwTIDCasein kinase II subunit alpha2.7.11.10.440
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.440