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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3raiX85Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3raiX85Cyclin-dependent kinase 22.7.11.221.000
3qx2X63Cyclin-dependent kinase 22.7.11.220.603
3r6xX84Cyclin-dependent kinase 22.7.11.220.603
3qxoX65Cyclin-dependent kinase 22.7.11.220.602
3rm719ZCyclin-dependent kinase 22.7.11.220.598
3roy22ZCyclin-dependent kinase 22.7.11.220.535
2btrU73Cyclin-dependent kinase 22.7.11.220.532
3r8vZ62Cyclin-dependent kinase 22.7.11.220.519
2c69CT8Cyclin-dependent kinase 22.7.11.220.514
2exmZIPCyclin-dependent kinase 22.7.11.220.513
1w8cN69Cyclin-dependent kinase 22.7.11.220.512
3qzgX67Cyclin-dependent kinase 22.7.11.220.504
1pxmCK5Cyclin-dependent kinase 22.7.11.220.501
3rahO1ZCyclin-dependent kinase 22.7.11.220.494
1gz8MBPCyclin-dependent kinase 22.7.11.220.493
2c6o4SPCyclin-dependent kinase 22.7.11.220.492
4ek610KCyclin-dependent kinase 22.7.11.220.492
3qwjX6ACyclin-dependent kinase 22.7.11.220.491
3r1qX75Cyclin-dependent kinase 22.7.11.220.489
3r83Z14Cyclin-dependent kinase 22.7.11.220.487
3s2pPMUCyclin-dependent kinase 22.7.11.220.487
3r8lZ30Cyclin-dependent kinase 22.7.11.220.486
3iggEFQCyclin-dependent kinase 22.7.11.220.483
3r73X87Cyclin-dependent kinase 22.7.11.220.483
2r3iSCFCyclin-dependent kinase 22.7.11.220.482
3r28XA0Cyclin-dependent kinase 22.7.11.220.482
3qu0X40Cyclin-dependent kinase 22.7.11.220.481
3qtxX43Cyclin-dependent kinase 22.7.11.220.480
3r1yX76Cyclin-dependent kinase 22.7.11.220.480
3r7yZ04Cyclin-dependent kinase 22.7.11.220.480
4fkpLS5Cyclin-dependent kinase 22.7.11.220.480
2r3p3SCCyclin-dependent kinase 22.7.11.220.478
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.478
3r9nZ68Cyclin-dependent kinase 22.7.11.220.475
4fkq42KCyclin-dependent kinase 22.7.11.220.475
4fkt48KCyclin-dependent kinase 22.7.11.220.474
2c6iDT1Cyclin-dependent kinase 22.7.11.220.473
3r7vZ02Cyclin-dependent kinase 22.7.11.220.473
2btsU32Cyclin-dependent kinase 22.7.11.220.471
2w06FRVCyclin-dependent kinase 22.7.11.220.471
3qqfX07Cyclin-dependent kinase 22.7.11.220.471
1h0w207Cyclin-dependent kinase 22.7.11.220.470
3r71X86Cyclin-dependent kinase 22.7.11.220.469
1ke5LS1Cyclin-dependent kinase 22.7.11.220.468
1p2a5BNCyclin-dependent kinase 22.7.11.220.467
1ykr628Cyclin-dependent kinase 22.7.11.220.464
3qtzX42Cyclin-dependent kinase 22.7.11.220.464
4fklCK2Cyclin-dependent kinase 22.7.11.220.463
3fz1B98Cyclin-dependent kinase 22.7.11.220.462
3qwkX62Cyclin-dependent kinase 22.7.11.220.462
1w0xOLOCyclin-dependent kinase 22.7.11.220.461
2r3r6SCCyclin-dependent kinase 22.7.11.220.461
4kd11QKCyclin-dependent kinase 22.7.11.220.461
3lfsA07Cyclin-dependent kinase 22.7.11.220.459
4ez30S0Cyclin-dependent kinase 22.7.11.220.459
2r3fSC8Cyclin-dependent kinase 22.7.11.220.458
3qqkX02Cyclin-dependent kinase 22.7.11.220.457
3sqq99ZCyclin-dependent kinase 22.7.11.220.457
1b38ATPCyclin-dependent kinase 22.7.11.220.456
2r3gSC9Cyclin-dependent kinase 22.7.11.220.456
3r1sX73Cyclin-dependent kinase 22.7.11.220.456
1ckpPVBCyclin-dependent kinase 22.7.11.220.455
4fki09KCyclin-dependent kinase 22.7.11.220.455
3r9hZ67Cyclin-dependent kinase 22.7.11.220.454
1ke6LS2Cyclin-dependent kinase 22.7.11.220.453
2vthLZ2Cyclin-dependent kinase 22.7.11.220.453
2c6lDT4Cyclin-dependent kinase 22.7.11.220.451
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.451
1y8yCT7Cyclin-dependent kinase 22.7.11.220.450
1gih1PUCyclin-dependent kinase 22.7.11.220.449
1v1k3FPCyclin-dependent kinase 22.7.11.220.448
3qtuX44Cyclin-dependent kinase 22.7.11.220.448
3rk909ZCyclin-dependent kinase 22.7.11.220.448
3rpo24ZCyclin-dependent kinase 22.7.11.220.448
1gii1PUCyclin-dependent kinase 22.7.11.220.447
1h0vUN4Cyclin-dependent kinase 22.7.11.220.447
1vyzN5BCyclin-dependent kinase 22.7.11.220.447
2a0cCK9Cyclin-dependent kinase 22.7.11.220.447
2uzoC62Cyclin-dependent kinase 22.7.11.220.446
3ig7EFPCyclin-dependent kinase 22.7.11.220.446
3pj8404Cyclin-dependent kinase 22.7.11.220.446
3rak03ZCyclin-dependent kinase 22.7.11.220.445
3rpr25ZCyclin-dependent kinase 22.7.11.220.445
1b39ATPCyclin-dependent kinase 22.7.11.220.444
3qtsX46Cyclin-dependent kinase 22.7.11.220.444
3s0o50ZCyclin-dependent kinase 22.7.11.220.444
1e1xNW1Cyclin-dependent kinase 22.7.11.220.443
3qruX19Cyclin-dependent kinase 22.7.11.220.443
4fkg4CKCyclin-dependent kinase 22.7.11.220.443
1oitHDTCyclin-dependent kinase 22.7.11.220.442
3lfnA27Cyclin-dependent kinase 22.7.11.220.442
3rk507ZCyclin-dependent kinase 22.7.11.220.442
2r3o2SCCyclin-dependent kinase 22.7.11.220.441
3rk708ZCyclin-dependent kinase 22.7.11.220.441
4fko20KCyclin-dependent kinase 22.7.11.220.441
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.440