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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r8lZ30Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r8lZ30Cyclin-dependent kinase 22.7.11.221.000
3lfnA27Cyclin-dependent kinase 22.7.11.220.573
1pxmCK5Cyclin-dependent kinase 22.7.11.220.551
3qzgX67Cyclin-dependent kinase 22.7.11.220.539
3r7yZ04Cyclin-dependent kinase 22.7.11.220.533
2a0cCK9Cyclin-dependent kinase 22.7.11.220.532
2c6o4SPCyclin-dependent kinase 22.7.11.220.532
2btrU73Cyclin-dependent kinase 22.7.11.220.530
3lfqA28Cyclin-dependent kinase 22.7.11.220.526
3r1yX76Cyclin-dependent kinase 22.7.11.220.526
3rkb12ZCyclin-dependent kinase 22.7.11.220.524
1ykr628Cyclin-dependent kinase 22.7.11.220.520
2exmZIPCyclin-dependent kinase 22.7.11.220.518
3r83Z14Cyclin-dependent kinase 22.7.11.220.516
1oitHDTCyclin-dependent kinase 22.7.11.220.515
4ek610KCyclin-dependent kinase 22.7.11.220.510
4fki09KCyclin-dependent kinase 22.7.11.220.506
4fkq42KCyclin-dependent kinase 22.7.11.220.504
1pxoCK7Cyclin-dependent kinase 22.7.11.220.500
2r3jSCJCyclin-dependent kinase 22.7.11.220.499
3rpo24ZCyclin-dependent kinase 22.7.11.220.499
3qxoX65Cyclin-dependent kinase 22.7.11.220.496
3iggEFQCyclin-dependent kinase 22.7.11.220.495
1w8cN69Cyclin-dependent kinase 22.7.11.220.493
1pxlCK4Cyclin-dependent kinase 22.7.11.220.491
3r8vZ62Cyclin-dependent kinase 22.7.11.220.490
3rk708ZCyclin-dependent kinase 22.7.11.220.490
1ke5LS1Cyclin-dependent kinase 22.7.11.220.489
3rm719ZCyclin-dependent kinase 22.7.11.220.489
3r7vZ02Cyclin-dependent kinase 22.7.11.220.488
4fkt48KCyclin-dependent kinase 22.7.11.220.488
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.485
3s1h56ZCyclin-dependent kinase 22.7.11.220.480
4fkv61KCyclin-dependent kinase 22.7.11.220.480
2b52D42Cyclin-dependent kinase 22.7.11.220.479
2uzoC62Cyclin-dependent kinase 22.7.11.220.479
3qwjX6ACyclin-dependent kinase 22.7.11.220.475
3rjc06ZCyclin-dependent kinase 22.7.11.220.475
3qqlX03Cyclin-dependent kinase 22.7.11.220.474
3sw719KCyclin-dependent kinase 22.7.11.220.474
4fkg4CKCyclin-dependent kinase 22.7.11.220.474
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.473
4kd11QKCyclin-dependent kinase 22.7.11.220.472
2vthLZ2Cyclin-dependent kinase 22.7.11.220.471
3rahO1ZCyclin-dependent kinase 22.7.11.220.470
2xmyCDKCyclin-dependent kinase 22.7.11.220.469
4fkj11KCyclin-dependent kinase 22.7.11.220.469
1b38ATPCyclin-dependent kinase 22.7.11.220.468
3fz1B98Cyclin-dependent kinase 22.7.11.220.468
1gii1PUCyclin-dependent kinase 22.7.11.220.467
2c6kDT2Cyclin-dependent kinase 22.7.11.220.467
3qtuX44Cyclin-dependent kinase 22.7.11.220.467
1w0xOLOCyclin-dependent kinase 22.7.11.220.465
2a4lRRCCyclin-dependent kinase 22.7.11.220.465
4fkpLS5Cyclin-dependent kinase 22.7.11.220.465
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.464
3rak03ZCyclin-dependent kinase 22.7.11.220.464
1g5sI17Cyclin-dependent kinase 22.7.11.220.463
3s2pPMUCyclin-dependent kinase 22.7.11.220.463
2c6lDT4Cyclin-dependent kinase 22.7.11.220.462
3qtzX42Cyclin-dependent kinase 22.7.11.220.462
3qu0X40Cyclin-dependent kinase 22.7.11.220.462
3wblPDYCyclin-dependent kinase 22.7.11.220.462
4ek816KCyclin-dependent kinase 22.7.11.220.462
4fklCK2Cyclin-dependent kinase 22.7.11.220.462
1oirHDYCyclin-dependent kinase 22.7.11.220.461
2vv9IM9Cyclin-dependent kinase 22.7.11.220.461
3ezvEZVCyclin-dependent kinase 22.7.11.220.461
4fkr45KCyclin-dependent kinase 22.7.11.220.461
1pxpCK8Cyclin-dependent kinase 22.7.11.220.460
1y91CT9Cyclin-dependent kinase 22.7.11.220.460
2btsU32Cyclin-dependent kinase 22.7.11.220.460
2c5yMTWCyclin-dependent kinase 22.7.11.220.459
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.459
4fko20KCyclin-dependent kinase 22.7.11.220.459
1hckATPCyclin-dependent kinase 22.7.11.220.458
2w06FRVCyclin-dependent kinase 22.7.11.220.457
3rni21ZCyclin-dependent kinase 22.7.11.220.457
3rpv26ZCyclin-dependent kinase 22.7.11.220.457
3qqhX0ACyclin-dependent kinase 22.7.11.220.456
2vu3LZECyclin-dependent kinase 22.7.11.220.453
4fks46KCyclin-dependent kinase 22.7.11.220.453
1ckpPVBCyclin-dependent kinase 22.7.11.220.452
3r9dX6BCyclin-dependent kinase 22.7.11.220.452
3raiX85Cyclin-dependent kinase 22.7.11.220.452
2b53D23Cyclin-dependent kinase 22.7.11.220.451
4acm7YGCyclin-dependent kinase 22.7.11.220.451
1y8yCT7Cyclin-dependent kinase 22.7.11.220.450
3r71X86Cyclin-dependent kinase 22.7.11.220.450
3pxyJWSCyclin-dependent kinase 22.7.11.220.449
3sw418KCyclin-dependent kinase 22.7.11.220.449
3qzhX69Cyclin-dependent kinase 22.7.11.220.448
3r7uX96Cyclin-dependent kinase 22.7.11.220.447
2r3lSCWCyclin-dependent kinase 22.7.11.220.446
4bgh3I6Cyclin-dependent kinase 22.7.11.220.445
3rm618ZCyclin-dependent kinase 22.7.11.220.444
1ke7LS3Cyclin-dependent kinase 22.7.11.220.442
1ke6LS2Cyclin-dependent kinase 22.7.11.220.441
4erwSTUCyclin-dependent kinase 22.7.11.220.440