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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r7yZ04Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r7yZ04Cyclin-dependent kinase 22.7.11.221.000
3r71X86Cyclin-dependent kinase 22.7.11.220.550
3qzgX67Cyclin-dependent kinase 22.7.11.220.492
3r1yX76Cyclin-dependent kinase 22.7.11.220.479
3qwjX6ACyclin-dependent kinase 22.7.11.220.475
3r83Z14Cyclin-dependent kinase 22.7.11.220.470
2c6o4SPCyclin-dependent kinase 22.7.11.220.461
3lfnA27Cyclin-dependent kinase 22.7.11.220.454
1w8cN69Cyclin-dependent kinase 22.7.11.220.449
3r8lZ30Cyclin-dependent kinase 22.7.11.220.445
4kd11QKCyclin-dependent kinase 22.7.11.220.442