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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r6iJMSAldo-keto reductase family 1 member C3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r6iJMSAldo-keto reductase family 1 member C3/1.000
3r7mSUZAldo-keto reductase family 1 member C3/0.661
4hmn16JAldo-keto reductase family 1 member C3/0.638
3r94FLRAldo-keto reductase family 1 member C3/0.624
3r58NPSAldo-keto reductase family 1 member C3/0.613
3r8gIZPAldo-keto reductase family 1 member C3/0.602
3r43ID8Aldo-keto reductase family 1 member C3/0.599
3uweVJJAldo-keto reductase family 1 member C3/0.599
1zq5E04Aldo-keto reductase family 1 member C3/0.591
1s2cFLFAldo-keto reductase family 1 member C3/0.580
4h7c10HAldo-keto reductase family 1 member C3/0.578
1ry0PG2Aldo-keto reductase family 1 member C3/0.570
2f3815MAldo-keto reductase family 1 member C3/0.542
4dbw511Aldo-keto reductase family 1 member C3/0.535
1s1rNAPAldo-keto reductase family 1 member C3/0.526
1ry8RUTAldo-keto reductase family 1 member C3/0.520
4fa30SLAldo-keto reductase family 1 member C3/0.520
4fam0SZAldo-keto reductase family 1 member C3/0.519
3r8hZOMAldo-keto reductase family 1 member C3/0.506
4fal0T0Aldo-keto reductase family 1 member C3/0.506
3ufyNPXAldo-keto reductase family 1 member C3/0.494
1xf0ASDAldo-keto reductase family 1 member C3/0.475
3ugrIMNAldo-keto reductase family 1 member C3/0.468
4dz5NAPAldo-keto reductase family 1 member C3/0.442