Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 1.000 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.542 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.527 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.523 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.516 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.516 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.514 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.514 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.511 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.505 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.502 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.502 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.502 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.497 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.496 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.494 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.492 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.491 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.490 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.489 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.487 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.487 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.487 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.487 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.487 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
| 2euf | LQQ | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.486 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.486 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.486 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.486 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.485 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.485 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.484 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.484 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.484 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.484 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.484 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.482 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.481 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.481 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 4fsu | HK5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.479 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.479 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.479 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.478 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.478 | |
| 1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.477 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.477 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.476 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.476 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.476 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.476 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.476 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.475 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.475 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.475 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.475 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.475 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.474 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.474 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.474 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.473 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.473 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.471 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.471 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.471 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.471 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.471 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.470 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 1p4f | DRG | Death-associated protein kinase 1 | 2.7.11.1 | 0.469 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.469 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.469 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.469 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.469 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.468 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.468 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.468 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.468 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.468 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.467 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.467 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.467 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.466 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.466 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.466 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 2uzd | C85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.465 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.464 | |
| 2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.464 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.464 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.464 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.464 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.463 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4iwd | 1JC | Hepatocyte growth factor receptor | 2.7.10.1 | 0.463 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.463 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.462 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.462 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.462 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.462 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.461 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.460 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.460 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.459 | |
| 1ke5 | LS1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.459 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.459 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.459 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.459 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.457 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.456 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.456 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.456 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.456 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 1pye | PM1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2uzn | C96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.455 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.454 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.454 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 5dpv | SKE | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.453 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 4kb9 | G79 | Protease | / | 0.453 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.451 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.451 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.451 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.450 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.450 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.450 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.450 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.450 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 1pxp | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.449 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2vti | LZ3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.449 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.448 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2nnp | ROC | Protease | / | 0.447 | |
| 2vtj | LZ4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3bhh | 5CP | Calcium/calmodulin-dependent protein kinase type II subunit beta | 2.7.11.17 | 0.447 | |
| 3lin | E13 | Protease | / | 0.447 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.447 | |
| 1fej | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 4fkg | 4CK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.446 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1c6x | 3IN | Protease | / | 0.445 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1rl8 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.445 | |
| 2bhe | BRY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.445 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.445 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.445 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.445 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.444 | |
| 1k1u | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 2aqu | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2qak | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 4ek6 | 10K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.444 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.443 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.443 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2b60 | RIT | Pol polyprotein | / | 0.443 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.443 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 1wbm | BLL | Pol protein | / | 0.442 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2p3a | 3TL | Pol protein | / | 0.442 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.442 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.442 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.442 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.442 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.441 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.441 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.441 | |
| 2p3c | 3TL | Protease | / | 0.441 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3s43 | 478 | Protease | / | 0.441 | |
| 3sa3 | 23X | Protease | / | 0.441 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.440 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.440 | |
| 1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1w5x | BE5 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1wbk | 568 | Pol protein | / | 0.440 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 2bpy | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.440 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.440 |