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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qwjX6ACyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qwjX6ACyclin-dependent kinase 22.7.11.221.000
3rk909ZCyclin-dependent kinase 22.7.11.220.490
3rkb12ZCyclin-dependent kinase 22.7.11.220.490
3r8vZ62Cyclin-dependent kinase 22.7.11.220.473
2fvdLIACyclin-dependent kinase 22.7.11.220.465
3r7yZ04Cyclin-dependent kinase 22.7.11.220.464
3r9dX6BCyclin-dependent kinase 22.7.11.220.463
3iggEFQCyclin-dependent kinase 22.7.11.220.452
3r1yX76Cyclin-dependent kinase 22.7.11.220.449
3r83Z14Cyclin-dependent kinase 22.7.11.220.448
3qu0X40Cyclin-dependent kinase 22.7.11.220.443