sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3qv2	SAH	5-cytosine DNA methyltransferase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3qv2	SAH	5-cytosine DNA methyltransferase	/	1.000
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.498
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.491
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.489
4h0n	SAH	Dnmt2	/	0.480
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.480
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.467
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.457
4da4	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.457
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.453
4wxx	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.451
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.449
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.440