sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3qts	X46	Cyclin-dependent kinase 2	2.7.11.22

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3qts	X46	Cyclin-dependent kinase 2	2.7.11.22	1.000
3r9n	Z68	Cyclin-dependent kinase 2	2.7.11.22	0.591
3rah	O1Z	Cyclin-dependent kinase 2	2.7.11.22	0.547
3r8v	Z62	Cyclin-dependent kinase 2	2.7.11.22	0.524
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22	0.515
3rpr	25Z	Cyclin-dependent kinase 2	2.7.11.22	0.500
1w8c	N69	Cyclin-dependent kinase 2	2.7.11.22	0.478
4fkl	CK2	Cyclin-dependent kinase 2	2.7.11.22	0.460
2c69	CT8	Cyclin-dependent kinase 2	2.7.11.22	0.448
3my5	RFZ	Cyclin-dependent kinase 2	2.7.11.22	0.448
2vtp	LZ9	Cyclin-dependent kinase 2	2.7.11.22	0.445