Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qqfX07Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qqfX07Cyclin-dependent kinase 22.7.11.221.000
3r73X87Cyclin-dependent kinase 22.7.11.220.762
3r7eX88Cyclin-dependent kinase 22.7.11.220.670
3qqkX02Cyclin-dependent kinase 22.7.11.220.651
3r1sX73Cyclin-dependent kinase 22.7.11.220.649
3rm719ZCyclin-dependent kinase 22.7.11.220.647
3qzgX67Cyclin-dependent kinase 22.7.11.220.635
3r71X86Cyclin-dependent kinase 22.7.11.220.635
3qzhX69Cyclin-dependent kinase 22.7.11.220.634
3roy22ZCyclin-dependent kinase 22.7.11.220.633
4ek610KCyclin-dependent kinase 22.7.11.220.631
1h0w207Cyclin-dependent kinase 22.7.11.220.626
3sqq99ZCyclin-dependent kinase 22.7.11.220.626
1vyzN5BCyclin-dependent kinase 22.7.11.220.625
3r1yX76Cyclin-dependent kinase 22.7.11.220.621
3rk708ZCyclin-dependent kinase 22.7.11.220.619
3qxoX65Cyclin-dependent kinase 22.7.11.220.618
1ke6LS2Cyclin-dependent kinase 22.7.11.220.610
3r7uX96Cyclin-dependent kinase 22.7.11.220.610
3s0o50ZCyclin-dependent kinase 22.7.11.220.605
3r6xX84Cyclin-dependent kinase 22.7.11.220.598
1pxkCK3Cyclin-dependent kinase 22.7.11.220.597
3ql8X01Cyclin-dependent kinase 22.7.11.220.596
1ke7LS3Cyclin-dependent kinase 22.7.11.220.595
3fz1B98Cyclin-dependent kinase 22.7.11.220.595
2btrU73Cyclin-dependent kinase 22.7.11.220.594
4fkq42KCyclin-dependent kinase 22.7.11.220.594
1gih1PUCyclin-dependent kinase 22.7.11.220.593
1ke5LS1Cyclin-dependent kinase 22.7.11.220.591
4fkpLS5Cyclin-dependent kinase 22.7.11.220.591
3r28XA0Cyclin-dependent kinase 22.7.11.220.590
1p2a5BNCyclin-dependent kinase 22.7.11.220.588
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.588
3iggEFQCyclin-dependent kinase 22.7.11.220.588
3rk507ZCyclin-dependent kinase 22.7.11.220.588
1v1k3FPCyclin-dependent kinase 22.7.11.220.586
3s2pPMUCyclin-dependent kinase 22.7.11.220.586
2w06FRVCyclin-dependent kinase 22.7.11.220.584
3qtuX44Cyclin-dependent kinase 22.7.11.220.584
3rk909ZCyclin-dependent kinase 22.7.11.220.584
3ezrEZRCyclin-dependent kinase 22.7.11.220.583
3qtzX42Cyclin-dependent kinase 22.7.11.220.583
4nj32KDCyclin-dependent kinase 22.7.11.220.583
3qruX19Cyclin-dependent kinase 22.7.11.220.581
3raiX85Cyclin-dependent kinase 22.7.11.220.579
2r64740Cyclin-dependent kinase 22.7.11.220.577
3r9hZ67Cyclin-dependent kinase 22.7.11.220.575
3qwjX6ACyclin-dependent kinase 22.7.11.220.574
1pxmCK5Cyclin-dependent kinase 22.7.11.220.573
4ez30S0Cyclin-dependent kinase 22.7.11.220.573
1ykr628Cyclin-dependent kinase 22.7.11.220.572
1oguST8Cyclin-dependent kinase 22.7.11.220.571
1pxoCK7Cyclin-dependent kinase 22.7.11.220.571
2c6o4SPCyclin-dependent kinase 22.7.11.220.570
3qx2X63Cyclin-dependent kinase 22.7.11.220.569
1oiqHDUCyclin-dependent kinase 22.7.11.220.568
3r7vZ02Cyclin-dependent kinase 22.7.11.220.568
2btsU32Cyclin-dependent kinase 22.7.11.220.567
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.567
1vyw292Cyclin-dependent kinase 22.7.11.220.565
3qziX72Cyclin-dependent kinase 22.7.11.220.565
3r1qX75Cyclin-dependent kinase 22.7.11.220.565
3rpv26ZCyclin-dependent kinase 22.7.11.220.565
3qx4X4BCyclin-dependent kinase 22.7.11.220.564
4lyn1YGCyclin-dependent kinase 22.7.11.220.564
3lfnA27Cyclin-dependent kinase 22.7.11.220.563
4fkg4CKCyclin-dependent kinase 22.7.11.220.563
2uzoC62Cyclin-dependent kinase 22.7.11.220.562
3sw418KCyclin-dependent kinase 22.7.11.220.562
4bgh3I6Cyclin-dependent kinase 22.7.11.220.562
2w05FRTCyclin-dependent kinase 22.7.11.220.561
2a0cCK9Cyclin-dependent kinase 22.7.11.220.560
2bhhRYUCyclin-dependent kinase 22.7.11.220.560
3r7iX9ICyclin-dependent kinase 22.7.11.220.560
3rmf20ZCyclin-dependent kinase 22.7.11.220.560
3qu0X40Cyclin-dependent kinase 22.7.11.220.559
3ral04ZCyclin-dependent kinase 22.7.11.220.559
2r3iSCFCyclin-dependent kinase 22.7.11.220.558
5aniES4Cyclin-dependent kinase 22.7.11.220.558
4fkr45KCyclin-dependent kinase 22.7.11.220.555
1oitHDTCyclin-dependent kinase 22.7.11.220.554
2vthLZ2Cyclin-dependent kinase 22.7.11.220.554
3r8lZ30Cyclin-dependent kinase 22.7.11.220.554
3rni21ZCyclin-dependent kinase 22.7.11.220.554
4fki09KCyclin-dependent kinase 22.7.11.220.554
1w0xOLOCyclin-dependent kinase 22.7.11.220.553
3ti1B49Cyclin-dependent kinase 22.7.11.220.551
1h1s4SPCyclin-dependent kinase 22.7.11.220.548
3qtxX43Cyclin-dependent kinase 22.7.11.220.548
4fkj11KCyclin-dependent kinase 22.7.11.220.547
1b39ATPCyclin-dependent kinase 22.7.11.220.545
1ke8LS4Cyclin-dependent kinase 22.7.11.220.545
1urwI1PCyclin-dependent kinase 22.7.11.220.545
3ezvEZVCyclin-dependent kinase 22.7.11.220.544
1dm2HMDCyclin-dependent kinase 22.7.11.220.543
1ke9LS5Cyclin-dependent kinase 22.7.11.220.543
3qrtX14Cyclin-dependent kinase 22.7.11.220.543
4fkt48KCyclin-dependent kinase 22.7.11.220.543
1w8cN69Cyclin-dependent kinase 22.7.11.220.542
4acm7YGCyclin-dependent kinase 22.7.11.220.542
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.541
3ddqRRCCyclin-dependent kinase 22.7.11.220.541
2wxvWXVCyclin-dependent kinase 22.7.11.220.540
3qtqX35Cyclin-dependent kinase 22.7.11.220.540
3rm618ZCyclin-dependent kinase 22.7.11.220.540
3s1h56ZCyclin-dependent kinase 22.7.11.220.539
2a4lRRCCyclin-dependent kinase 22.7.11.220.538
1oi9N20Cyclin-dependent kinase 22.7.11.220.537
3ddpRC8Cyclin-dependent kinase 22.7.11.220.536
1ckpPVBCyclin-dependent kinase 22.7.11.220.535
3ig7EFPCyclin-dependent kinase 22.7.11.220.535
3qwkX62Cyclin-dependent kinase 22.7.11.220.535
1y91CT9Cyclin-dependent kinase 22.7.11.220.534
2r3p3SCCyclin-dependent kinase 22.7.11.220.534
3lfqA28Cyclin-dependent kinase 22.7.11.220.534
4eos1ROCyclin-dependent kinase 22.7.11.220.534
4fx360KCyclin-dependent kinase 22.7.11.220.533
1g5sI17Cyclin-dependent kinase 22.7.11.220.532
1r78FMDCyclin-dependent kinase 22.7.11.220.531
2j9mPY8Cyclin-dependent kinase 22.7.11.220.531
2wpa889Cyclin-dependent kinase 22.7.11.220.531
2iw94SPCyclin-dependent kinase 22.7.11.220.530
2r3lSCWCyclin-dependent kinase 22.7.11.220.530
4cfnJYMCyclin-dependent kinase 22.7.11.220.529
1di8DTQCyclin-dependent kinase 22.7.11.220.528
2c6iDT1Cyclin-dependent kinase 22.7.11.220.528
1h1r6CPCyclin-dependent kinase 22.7.11.220.527
2exmZIPCyclin-dependent kinase 22.7.11.220.527
3r8pZ46Cyclin-dependent kinase 22.7.11.220.527
3rpy27ZCyclin-dependent kinase 22.7.11.220.527
3tnwF18Cyclin-dependent kinase 22.7.11.220.527
4kd11QKCyclin-dependent kinase 22.7.11.220.526
2xmyCDKCyclin-dependent kinase 22.7.11.220.525
3wblPDYCyclin-dependent kinase 22.7.11.220.525
4bcpT3CCyclin-dependent kinase 22.7.11.220.525
1e1vCMGCyclin-dependent kinase 22.7.11.220.524
1oiyN41Cyclin-dependent kinase 22.7.11.220.524
3qqlX03Cyclin-dependent kinase 22.7.11.220.524
2vtsLZCCyclin-dependent kinase 22.7.11.220.523
1pyePM1Cyclin-dependent kinase 22.7.11.220.522
2b52D42Cyclin-dependent kinase 22.7.11.220.522
2r3kSCQCyclin-dependent kinase 22.7.11.220.521
2vu3LZECyclin-dependent kinase 22.7.11.220.521
3qzfX66Cyclin-dependent kinase 22.7.11.220.521
3r83Z14Cyclin-dependent kinase 22.7.11.220.521
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.519
2fvdLIACyclin-dependent kinase 22.7.11.220.518
2r3mSCXCyclin-dependent kinase 22.7.11.220.518
1finATPCyclin-dependent kinase 22.7.11.220.517
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.516
3uli1N3Cyclin-dependent kinase 22.7.11.220.515
2iw84SPCyclin-dependent kinase 22.7.11.220.513
2r3o2SCCyclin-dependent kinase 22.7.11.220.512
3unj0BXCyclin-dependent kinase 22.7.11.220.512
1gij2PUCyclin-dependent kinase 22.7.11.220.511
3lfsA07Cyclin-dependent kinase 22.7.11.220.511
2c4g514Cyclin-dependent kinase 22.7.11.220.510
2uznC96Cyclin-dependent kinase 22.7.11.220.510
3rkb12ZCyclin-dependent kinase 22.7.11.220.510
4eok4SPCyclin-dependent kinase 22.7.11.220.510
3rahO1ZCyclin-dependent kinase 22.7.11.220.509
3rak03ZCyclin-dependent kinase 22.7.11.220.509
2wihP48Cyclin-dependent kinase 22.7.11.220.508
4eor4SPCyclin-dependent kinase 22.7.11.220.508
4fko20KCyclin-dependent kinase 22.7.11.220.508
1gz8MBPCyclin-dependent kinase 22.7.11.220.506
2c6mDT5Cyclin-dependent kinase 22.7.11.220.506
4bcnT9NCyclin-dependent kinase 22.7.11.220.506
2b55D31Cyclin-dependent kinase 22.7.11.220.505
2b54D05Cyclin-dependent kinase 22.7.11.220.504
2c69CT8Cyclin-dependent kinase 22.7.11.220.503
2uzlC94Cyclin-dependent kinase 22.7.11.220.503
2w1hL0FCyclin-dependent kinase 22.7.11.220.503
4eon1ROCyclin-dependent kinase 22.7.11.220.503
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.502
3qtwX3ACyclin-dependent kinase 22.7.11.220.502
4fkw62KCyclin-dependent kinase 22.7.11.220.502
1fvt106Cyclin-dependent kinase 22.7.11.220.501
1h0vUN4Cyclin-dependent kinase 22.7.11.220.501
2r3r6SCCyclin-dependent kinase 22.7.11.220.501
3r8zZ63Cyclin-dependent kinase 22.7.11.220.500
3rjc06ZCyclin-dependent kinase 22.7.11.220.500
1oiuN76Cyclin-dependent kinase 22.7.11.220.498
2vttLZDCyclin-dependent kinase 22.7.11.220.498
3bhtMFRCyclin-dependent kinase 22.7.11.220.498
1unlRRCCyclin-dependent-like kinase 52.7.11.10.497
3unk0BYCyclin-dependent kinase 22.7.11.220.497
1e9hINRCyclin-dependent kinase 22.7.11.220.495
1fvv107Cyclin-dependent kinase 22.7.11.220.495
1gii1PUCyclin-dependent kinase 22.7.11.220.495
3sw719KCyclin-dependent kinase 22.7.11.220.495
4fklCK2Cyclin-dependent kinase 22.7.11.220.495
4fks46KCyclin-dependent kinase 22.7.11.220.495
3pj8404Cyclin-dependent kinase 22.7.11.220.494
3py0SU9Cyclin-dependent kinase 22.7.11.220.494
2duv371Cyclin-dependent kinase 22.7.11.220.493
3my5RFZCyclin-dependent kinase 22.7.11.220.493
3r8uZ31Cyclin-dependent kinase 22.7.11.220.493
1e1xNW1Cyclin-dependent kinase 22.7.11.220.492
1pkdUCNCyclin-dependent kinase 22.7.11.220.492
2i40BLZCyclin-dependent kinase 22.7.11.220.492
4qmpDKISerine/threonine-protein kinase 242.7.11.10.492
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.491
3dogNNNCyclin-dependent kinase 22.7.11.220.491
4fkv61KCyclin-dependent kinase 22.7.11.220.491
3r9dX6BCyclin-dependent kinase 22.7.11.220.489
4eomATPCyclin-dependent kinase 22.7.11.220.489
3rzb02ZCyclin-dependent kinase 22.7.11.220.488
3tiz3TICyclin-dependent kinase 22.7.11.220.487
2c5nCK8Cyclin-dependent kinase 22.7.11.220.486
2r3gSC9Cyclin-dependent kinase 22.7.11.220.485
2x1nX1NCyclin-dependent kinase 22.7.11.220.478
4bcoT6QCyclin-dependent kinase 22.7.11.220.478
4eol1ROCyclin-dependent kinase 22.7.11.220.478
2xnbY8LCyclin-dependent kinase 22.7.11.220.477
4eop1ROCyclin-dependent kinase 22.7.11.220.477
2vv9IM9Cyclin-dependent kinase 22.7.11.220.475
4ii5ADPCyclin-dependent kinase 22.7.11.220.475
1pxpCK8Cyclin-dependent kinase 22.7.11.220.474
3rpr25ZCyclin-dependent kinase 22.7.11.220.473
2uzdC85Cyclin-dependent kinase 22.7.11.220.472
2b53D23Cyclin-dependent kinase 22.7.11.220.471
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.471
1h1q2A6Cyclin-dependent kinase 22.7.11.220.470
2w17I19Cyclin-dependent kinase 22.7.11.220.470
2cchATPCyclin-dependent kinase 22.7.11.220.469
2c6lDT4Cyclin-dependent kinase 22.7.11.220.468
3r9nZ68Cyclin-dependent kinase 22.7.11.220.468
4eoi1ROCyclin-dependent kinase 22.7.11.220.467
3sheI85MAP kinase-activated protein kinase 32.7.11.10.466
3pxyJWSCyclin-dependent kinase 22.7.11.220.465
5dr6SKEAurora kinase A2.7.11.10.465
2vtqLZACyclin-dependent kinase 22.7.11.220.463
2wotZZGTGF-beta receptor type-12.7.11.300.463
1eh4IC1Casein kinase I homolog 12.7.11.10.462
1b38ATPCyclin-dependent kinase 22.7.11.220.461
4i3zADPCyclin-dependent kinase 22.7.11.220.461
2c6tDT5Cyclin-dependent kinase 22.7.11.220.460
5aacVGHALK tyrosine kinase receptor2.7.10.10.459
3ggfGVDSerine/threonine-protein kinase 26/0.457
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.457
2r3jSCJCyclin-dependent kinase 22.7.11.220.456
2uzeC95Cyclin-dependent kinase 22.7.11.220.456
3gxlQIGTGF-beta receptor type-12.7.11.300.456
3r9oZ71Cyclin-dependent kinase 22.7.11.220.455
4bcqTJFCyclin-dependent kinase 22.7.11.220.454
4qmlANPSerine/threonine-protein kinase 242.7.11.10.453
1hckATPCyclin-dependent kinase 22.7.11.220.452
1y8yCT7Cyclin-dependent kinase 22.7.11.220.452
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.452
3qqhX0ACyclin-dependent kinase 22.7.11.220.451
4au8Z3RCyclin-dependent-like kinase 52.7.11.10.451
1vjy460TGF-beta receptor type-12.7.11.300.450
2xikJ60Serine/threonine-protein kinase 252.7.11.10.450
4fob0USALK tyrosine kinase receptor2.7.10.10.450
4qmySTUSerine/threonine-protein kinase 242.7.11.10.450
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.449
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.449
2bkzSBCCyclin-dependent kinase 22.7.11.220.448
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.448
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.448
1gy3ATPCyclin-dependent kinase 22.7.11.220.447
2c5yMTWCyclin-dependent kinase 22.7.11.220.447
3nynSGVG protein-coupled receptor kinase 62.7.11.160.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
1h1pCMGCyclin-dependent kinase 22.7.11.220.445
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.445
5aaaVGHALK tyrosine kinase receptor2.7.10.10.445
3mvl38PMitogen-activated protein kinase 14/0.444
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.444
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4qmzB49Serine/threonine-protein kinase 242.7.11.10.443
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.442
3s00Z60Cyclin-dependent kinase 22.7.11.220.442
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.442
3gubGUBDeath-associated protein kinase 12.7.11.10.441
2r3fSC8Cyclin-dependent kinase 22.7.11.220.440
3qtrX36Cyclin-dependent kinase 22.7.11.220.440
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.440