Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.651 | |
1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.649 | |
1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.647 | |
1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.642 | |
4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.640 | |
4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.614 | |
3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.613 | |
3qly | 55V | Uncharacterized protein | / | 0.605 | |
3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.604 | |
3eek | 53S | Uncharacterized protein | / | 0.602 | |
1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.600 | |
3cse | N22 | Uncharacterized protein | / | 0.600 | |
3qlx | QLR | Uncharacterized protein | / | 0.596 | |
4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.596 | |
3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.594 | |
1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.593 | |
3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.588 | |
1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.585 | |
3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.584 | |
2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.583 | |
3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.583 | |
2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.582 | |
3eem | 53V | Uncharacterized protein | / | 0.579 | |
3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.576 | |
1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.574 | |
3eej | 53R | Uncharacterized protein | / | 0.573 | |
4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.571 | |
2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.569 | |
3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.569 | |
3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.568 | |
3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.567 | |
3eel | 53T | Uncharacterized protein | / | 0.566 | |
4h98 | 14Q | Uncharacterized protein | / | 0.565 | |
1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.558 | |
3qlz | QLZ | Uncharacterized protein | / | 0.558 | |
3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.557 | |
4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.554 | |
1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.553 | |
1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.551 | |
2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.546 | |
3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.546 | |
4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.545 | |
1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.543 | |
3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.541 | |
1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
2w3v | TOP | Dihydrofolate reductase | / | 0.538 | |
2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.531 | |
4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
2zza | FOL | Dihydrofolate reductase | / | 0.528 | |
1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.526 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.523 | |
3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.516 | |
3jwm | 5WB | Dihydrofolate reductase | / | 0.516 | |
3sa1 | 6DR | Dihydrofolate reductase | / | 0.515 | |
3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
3tq9 | MTX | Dihydrofolate reductase | / | 0.514 | |
4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.507 | |
3jwc | EKB | Dihydrofolate reductase | / | 0.505 | |
3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.505 | |
4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.504 | |
3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.502 | |
1og5 | SWF | Cytochrome P450 2C9 | / | 0.501 | |
3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
3tqb | FOL | Dihydrofolate reductase | / | 0.495 | |
7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
3jw5 | TOP | Dihydrofolate reductase | / | 0.493 | |
3ia4 | MTX | Dihydrofolate reductase | / | 0.492 | |
1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.491 | |
3sai | 9DR | Dihydrofolate reductase | / | 0.491 | |
1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.486 | |
4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.484 | |
4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
1fmj | RTL | Retinol dehydratase | / | 0.482 | |
2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.480 | |
3sa2 | 7DR | Dihydrofolate reductase | / | 0.480 | |
1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
3vt5 | YI2 | Vitamin D3 receptor | / | 0.479 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.477 | |
4fhf | 0TT | Spore photoproduct lyase | / | 0.477 | |
4p66 | MTX | Dihydrofolate reductase | / | 0.477 | |
3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
3gwf | NAP | Cyclohexanone monooxygenase | / | 0.473 | |
3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
4j6c | STR | Cytochrome P450 monooxygenase | / | 0.472 | |
4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.470 | |
4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.470 | |
3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.469 | |
3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
3mg3 | ECH | Orange carotenoid-binding protein | / | 0.469 | |
4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.468 | |
2w3w | VG9 | Dihydrofolate reductase | / | 0.467 | |
3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.466 | |
1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
3bfa | 9OD | Odorant binding protein ASP1 | / | 0.465 | |
4ele | 31I | Dihydrofolate reductase | / | 0.465 | |
1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.464 | |
1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.462 | |
3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
3kpz | ZNE | Vitamin D3 receptor | / | 0.461 | |
3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.459 | |
1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
2zlc | VDX | Vitamin D3 receptor | / | 0.458 | |
3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.458 | |
3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.458 | |
4cuk | NAI | D-lactate dehydrogenase | / | 0.458 | |
4ia1 | BIV | Vitamin D3 receptor A | / | 0.458 | |
5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.458 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.458 | |
2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.457 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
1cjk | FOK | Adenylate cyclase type 2 | / | 0.456 | |
1cjk | FOK | Adenylate cyclase type 5 | / | 0.456 | |
1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.456 | |
4zas | TYD | CalS13 | / | 0.456 | |
1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
4ia7 | BIV | Vitamin D3 receptor A | / | 0.455 | |
1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
4iui | 1GQ | Estrogen receptor | / | 0.454 | |
4m7v | RAR | Dihydrofolate reductase | / | 0.454 | |
1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
1d2s | DHT | Sex hormone-binding globulin | / | 0.452 | |
1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
4enh | FVX | Cholesterol 24-hydroxylase | / | 0.452 | |
1ie9 | VDX | Vitamin D3 receptor | / | 0.451 | |
1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.451 | |
3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
3ngl | NAP | Bifunctional protein FolD | / | 0.451 | |
3tq8 | TOP | Dihydrofolate reductase | / | 0.451 | |
4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.450 | |
3fl8 | RAR | Dihydrofolate reductase | / | 0.450 | |
4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.450 | |
4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
4p68 | MTX | Dihydrofolate reductase | / | 0.450 | |
1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.449 | |
1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.449 | |
1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
4iv2 | 1GR | Estrogen receptor | / | 0.449 | |
4j6d | TES | Cytochrome P450 monooxygenase | / | 0.449 | |
1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.448 | |
1pp9 | SMA | Cytochrome b | / | 0.448 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
3vtc | TK3 | Vitamin D3 receptor | / | 0.448 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.448 | |
4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
1x8l | OXR | Retinol dehydratase | / | 0.447 | |
2acw | UPG | Glycosyltransferase | / | 0.447 | |
2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.447 | |
3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.447 | |
4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.447 | |
1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.446 | |
2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
4g1z | 0VP | Vitamin D3 receptor A | / | 0.446 | |
4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.446 | |
1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
2jfa | RAL | Estrogen receptor | / | 0.444 | |
3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
3vt6 | 5YI | Vitamin D3 receptor | / | 0.444 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
4l9q | 9TP | Serum albumin | / | 0.443 | |
4ug7 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.443 | |
1kij | NOV | DNA gyrase subunit B | / | 0.442 | |
3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.442 | |
3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.442 | |
3k1w | BFX | Renin | 3.4.23.15 | 0.442 | |
4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.442 | |
4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
3ert | OHT | Estrogen receptor | / | 0.441 | |
3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
2bxm | IMN | Serum albumin | / | 0.440 | |
2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.440 | |
2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.440 | |
3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.440 | |
3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.440 |