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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.11.000
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.721
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.627
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.495
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.493
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.486
4ysjADPCalmodulin-like domain protein kinase/0.471
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.464
2w4jADPDeath-associated protein kinase 12.7.11.10.457
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.456
1ig1ANPDeath-associated protein kinase 12.7.11.10.454
3ztxZTXAurora kinase B-A2.7.11.10.452
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.451
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.451
4i5cC5ITyrosine-protein kinase JAK1/0.451
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.449
4hvi19STyrosine-protein kinase JAK32.7.10.20.449
1jklANPDeath-associated protein kinase 12.7.11.10.447