sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3qcl	NXV	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3qcl	NXV	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	1.000
3qck	NX5	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.674
3qch	NX2	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.657
3qci	NX3	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.646
3qcj	NX4	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.582
3qcm	NXW	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.521
3qce	NXY	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.479
3qcf	NXY	Receptor-type tyrosine-protein phosphatase gamma	3.1.3.48	0.479
1xuo	LA1	Integrin alpha-L	/	0.451
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.445
4gdy	0X1	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.444