sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 1.000 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.510 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.505 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.500 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.497 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.485 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.482 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.476 | |
| 4irn | FAD | AnaB | / | 0.473 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.470 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.461 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.458 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.452 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.452 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.444 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.442 |