sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pej | BC2 | Endoplasmin homolog, putative |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3pej | BC2 | Endoplasmin homolog, putative | / | 1.000 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.601 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.601 | |
| 2exl | GDM | Endoplasmin | / | 0.590 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.578 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.566 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.561 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.558 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.554 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.552 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.548 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.544 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.542 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.525 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 1u0z | RDC | Endoplasmin | / | 0.519 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.519 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2esa | GDM | Endoplasmin | / | 0.515 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.514 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.514 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.505 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.503 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.498 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.496 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.496 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.496 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.495 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 1qy5 | NEC | Endoplasmin | / | 0.494 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.491 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.491 | |
| 2fyp | RDE | Endoplasmin | / | 0.490 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.490 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.489 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 2gqp | PA7 | Endoplasmin | / | 0.486 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.483 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.483 | |
| 1i58 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.482 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.482 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.482 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.480 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.478 | |
| 3ied | AN2 | HSP90 | / | 0.478 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.477 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.477 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.476 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.476 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.475 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.475 | |
| 1u0y | PA7 | Endoplasmin | / | 0.474 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.473 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.473 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.471 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.468 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.468 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.468 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.468 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.467 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.467 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.466 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.466 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.466 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.465 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.465 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.463 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.462 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.461 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.461 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.461 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.460 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 1ysz | NEC | Endoplasmin | / | 0.459 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.459 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.459 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.459 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.458 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.457 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.457 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.456 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.456 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.456 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.456 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.456 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.456 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.456 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.456 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.455 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.455 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.455 | |
| 1nja | DCM | Thymidylate synthase | / | 0.455 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.455 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.455 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.454 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.454 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.453 | |
| 1qy8 | RDI | Endoplasmin | / | 0.453 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.453 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.453 | |
| 2hch | N5A | Endoplasmin | / | 0.453 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.453 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.453 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 2gfd | RDA | Endoplasmin | / | 0.452 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.452 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.452 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.451 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.451 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 2q8i | RDC | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | 2.7.11.2 | 0.451 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.451 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.451 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.451 | |
| 3wec | AUI | Cytochrome P450 | / | 0.451 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.450 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.450 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.450 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.449 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.449 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.449 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.449 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.449 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.449 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.448 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 3jvw | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.448 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.448 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.448 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.447 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.447 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.447 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.447 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.447 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4ein | NOH | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.447 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.447 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.447 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.446 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.446 | |
| 4yqf | GDP | Septin-9 | / | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.445 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 1wbs | LI2 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.445 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.445 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.445 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.445 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.445 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.445 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.445 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4egn | TWO | Cytochrome P450 | / | 0.445 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1own | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.444 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.444 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2eld | SAH | Diphthine synthase | / | 0.444 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.444 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3zvv | XAZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.444 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.443 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.443 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.443 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.443 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2tdm | UMP | Thymidylate synthase | / | 0.443 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.443 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.442 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.442 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.442 | |
| 1yt0 | ADP | Endoplasmin | / | 0.442 | |
| 2ejz | SAH | Diphthine synthase | / | 0.442 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.442 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.442 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.442 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.442 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.442 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.442 | |
| 4mk0 | 29X | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.442 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.442 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.442 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.442 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.442 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.441 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.441 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.441 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.441 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 3cse | N22 | Uncharacterized protein | / | 0.441 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.441 | |
| 3p9t | TCL | Repressor | / | 0.441 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3ugc | 046 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.441 | |
| 4l8u | 9AZ | Serum albumin | / | 0.441 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.440 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2g86 | UMP | Thymidylate synthase | / | 0.440 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.440 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 |