sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 1.000 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.620 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.613 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.585 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.581 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.574 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.569 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.564 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.563 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.560 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.558 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.555 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.549 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.543 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.539 | |
| 4rrb | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.525 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.524 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.521 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.504 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.503 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.493 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.485 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.484 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.484 | |
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.483 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.482 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.482 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.481 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.477 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.477 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.477 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.475 | |
| 4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.475 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.475 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.471 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.470 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.469 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.469 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.468 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.468 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.467 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.466 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.465 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.464 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.464 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.462 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.462 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.462 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.462 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.461 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.461 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.460 | |
| 3q9w | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.459 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 4l44 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.459 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.459 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.458 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.457 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.457 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.457 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.457 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.457 | |
| 4ivd | 15T | Tyrosine-protein kinase JAK1 | / | 0.457 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.456 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.456 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.456 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.455 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.455 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.454 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.454 | |
| 3zvv | XAZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.453 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.453 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.453 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.453 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.452 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.452 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.452 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.452 | |
| 5dp2 | NAP | CurF | / | 0.452 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.452 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.451 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.451 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.451 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.450 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.449 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.449 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.449 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.449 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.447 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.447 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.447 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.447 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.447 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1sre | HAB | Streptavidin | / | 0.446 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.446 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.446 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.446 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.446 | |
| 5im3 | DTP | Ribonucleoside-diphosphate reductase | / | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3rdq | DTB | Streptavidin | / | 0.445 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.445 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.444 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.444 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.444 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.443 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.443 | |
| 1ppj | ANY | Cytochrome b | / | 0.443 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.443 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.443 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.443 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.443 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.443 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.442 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.442 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.442 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2jjj | 0QS | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 2ohv | NHL | Glutamate racemase | / | 0.441 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.441 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.441 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.441 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.440 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.440 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.440 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.440 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.440 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.440 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.440 | |
| 5a3c | NAD | SIR2 family protein | / | 0.440 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |