sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3p2v | DOY | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 1.000 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.667 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.637 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.625 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.623 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.618 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.616 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.614 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.609 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.609 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.605 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.603 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.601 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.599 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.598 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.592 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.585 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.559 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.558 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.557 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.553 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.552 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.547 | |
| 2acq | NAP | Aldose reductase | 1.1.1.21 | 0.531 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.529 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.528 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.513 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.508 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.508 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.505 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.500 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.500 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.499 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.499 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.494 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.493 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.491 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.491 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 3cv7 | C2U | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.489 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.489 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.489 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.489 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.489 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.488 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.488 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.487 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.487 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.486 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.485 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.485 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.485 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.484 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.483 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.483 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.482 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.482 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.481 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.481 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.479 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.478 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.478 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.478 | |
| 1az1 | ALR | Aldose reductase | 1.1.1.21 | 0.477 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.477 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.477 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.477 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.477 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.476 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.476 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.476 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.475 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.475 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.475 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 2f59 | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | / | 0.474 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.474 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
| 4j7g | TRH | PCZA361.3 | / | 0.474 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.473 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.473 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.473 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.473 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.472 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.472 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.472 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.472 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.471 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.471 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.471 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.469 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.469 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.469 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.469 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.468 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 1e6z | NGO | Chitinase | / | 0.467 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.467 | |
| 1rxj | BNI | Streptavidin | / | 0.467 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.467 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.467 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.467 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.466 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.466 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.465 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.465 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.465 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.464 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.464 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.464 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.464 | |
| 3h7u | NAP | NADPH-dependent aldo-keto reductase, chloroplastic | / | 0.464 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.464 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.464 | |
| 1jf2 | CZH | Obelin | / | 0.463 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.463 | |
| 3ean | NAP | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.463 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.463 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.463 | |
| 4kn0 | MTX | Folate receptor beta | / | 0.463 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.462 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.462 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.462 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.462 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.462 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.461 | |
| 2nvd | ITB | Aldose reductase | 1.1.1.21 | 0.461 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.461 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.461 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.461 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.461 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1u08 | PLP | Methionine aminotransferase | / | 0.460 | |
| 2dsc | APR | ADP-sugar pyrophosphatase | 3.6.1.13 | 0.460 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.460 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.460 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 4kn2 | LYA | Folate receptor beta | / | 0.460 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.460 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.459 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.459 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.459 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.459 | |
| 3ocw | 3AM | Lipoprotein E | / | 0.459 | |
| 3ocx | 2AM | Lipoprotein E | / | 0.459 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.458 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.458 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.458 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.457 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 2bd0 | BIO | Sepiapterin reductase | / | 0.457 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.457 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.457 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.457 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.456 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.456 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.456 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.456 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.456 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.455 | |
| 3htj | ET | EbrA repressor | / | 0.455 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4zas | TYD | CalS13 | / | 0.455 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.455 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.454 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.454 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.454 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4bvh | AR6 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.454 | |
| 4mbs | MRV | C-C chemokine receptor type 5 | / | 0.454 | |
| 4mrx | CZH | Obelin | / | 0.454 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.454 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1sqi | 869 | 4-hydroxyphenylpyruvate dioxygenase | / | 0.453 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2pev | NDP | Aldose reductase | 1.1.1.21 | 0.453 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3o3r | NAP | Aldose reductase-related protein 1 | 1.1.1.21 | 0.453 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.452 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.452 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.452 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.452 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.451 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.451 | |
| 2h7j | H7J | Cathepsin S | 3.4.22.27 | 0.451 | |
| 2qjp | ANJ | Cytochrome b | / | 0.451 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.451 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.451 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.450 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.450 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.450 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.450 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.450 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.450 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.450 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.450 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.450 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
| 1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.449 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.449 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.449 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.449 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.449 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.449 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.449 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.449 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.449 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.449 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.449 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1isj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.448 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.448 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.448 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.448 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.448 | |
| 4j7h | TRH | PCZA361.3 | / | 0.448 | |
| 4q7f | 3D1 | Uncharacterized protein | / | 0.448 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.447 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.447 | |
| 1s36 | CEI | Obelin | / | 0.447 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.447 | |
| 3c1o | NAP | Eugenol synthase | / | 0.447 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.446 | |
| 1qsn | COA | HAT A1 | / | 0.446 | |
| 1qv0 | CZH | Obelin | / | 0.446 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.446 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.446 | |
| 2pf8 | NDP | Aldose reductase | 1.1.1.21 | 0.446 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.446 | |
| 3e6e | DCS | Alanine racemase | / | 0.446 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.445 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.445 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2pfh | NDP | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 3arp | DEQ | Chitinase A | / | 0.445 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.445 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.445 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3ufy | NPX | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1el4 | CTZ | Obelin | / | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.444 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.444 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.444 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.444 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.444 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.444 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.444 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.444 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.444 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 4phl | PIL | Phosphodiesterase | / | 0.444 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.443 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.443 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.443 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.443 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4kmz | FOL | Folate receptor beta | / | 0.443 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.442 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4x3u | SVR | Chromobox protein homolog 7 | / | 0.442 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.441 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.441 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3u3o | 3QV | Sulfotransferase 1A1 | 2.8.2.1 | 0.441 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.441 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.441 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.440 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.440 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.440 | |
| 3pzc | GAP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.440 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.440 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4fh5 | UTP | Terminal uridylyltransferase cid1 | / | 0.440 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 |