sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.941 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.875 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.870 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.866 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.857 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.841 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.829 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.814 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.810 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.806 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.805 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.795 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.794 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.772 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.749 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.622 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.608 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.603 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.592 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.586 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.581 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.571 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.561 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.559 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.557 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.548 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.533 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.522 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.518 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.518 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.513 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.511 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.507 | |
| 4iae | 1DX | Alr2278 protein | / | 0.498 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.497 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.497 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.497 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.486 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.485 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.483 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.482 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.481 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.481 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.480 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.479 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.479 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.479 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.479 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.478 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.478 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.478 | |
| 4iah | 1DX | Alr2278 protein | / | 0.478 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.478 | |
| 4jic | FMN | GTN Reductase | / | 0.476 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.473 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.473 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.473 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.471 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.471 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.470 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.469 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.469 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.468 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.468 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.468 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.467 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.467 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.466 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.465 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.464 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.464 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.464 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 4j7h | TRH | PCZA361.3 | / | 0.462 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.462 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.461 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.461 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.461 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.460 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.460 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.460 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.460 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.458 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.458 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.458 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.457 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.457 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 2e77 | FMN | Lactate oxidase | / | 0.456 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.456 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.456 | |
| 4e2b | FMN | Dehydrogenase | / | 0.456 | |
| 4e2d | FMN | Dehydrogenase | / | 0.456 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.455 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.455 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.455 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.454 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.454 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.452 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.452 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.452 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.451 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.451 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.451 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.450 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 3e6e | DCS | Alanine racemase | / | 0.450 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.450 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.450 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.450 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.450 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.450 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.450 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.449 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.449 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.449 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.449 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.449 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.448 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.448 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.448 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.448 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.448 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.447 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.447 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.447 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.447 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.447 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.446 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.446 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.445 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.445 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.445 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.445 | |
| 3wag | TYD | Glycosyltransferase | / | 0.445 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.445 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.444 | |
| 2ohv | NHL | Glutamate racemase | / | 0.444 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.444 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.444 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.444 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.444 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.443 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.443 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.443 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.443 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.443 | |
| 4n1g | CEI | Obelin | / | 0.443 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.443 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.442 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.442 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.442 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.442 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.442 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.442 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.442 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.442 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1e2n | RCA | Thymidine kinase | / | 0.441 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.441 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.441 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.441 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.441 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.441 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.441 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.441 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.441 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.441 | |
| 3vp6 | HLD | Glutamate decarboxylase 1 | 4.1.1.15 | 0.441 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.441 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.440 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3lu1 | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.440 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.440 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.440 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.440 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.440 |