sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 1.000 | |
| 3owy | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.687 | |
| 1gs3 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.612 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.610 | |
| 1ogx | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.600 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.600 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.600 | |
| 1e3r | AND | Steroid Delta-isomerase | 5.3.3.1 | 0.573 | |
| 1oho | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.566 | |
| 1w6y | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.565 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.564 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.556 | |
| 3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.535 | |
| 1oh0 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.521 | |
| 3nhx | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.511 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.507 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.501 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.500 | |
| 1qjg | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.499 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.499 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.497 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.497 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.496 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.495 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.494 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.489 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.489 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.489 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.488 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.488 | |
| 1eio | GCH | Gastrotropin | / | 0.487 | |
| 4l9q | 9TP | Serum albumin | / | 0.487 | |
| 2bun | FAD | AppA protein | / | 0.486 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.486 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.484 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.484 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.484 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.483 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.481 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.481 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.480 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.480 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.479 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.479 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.479 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.478 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.478 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.477 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.477 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.477 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.476 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.476 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.476 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.476 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.475 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.475 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.475 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.475 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.474 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.474 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.474 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.474 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.473 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.473 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.473 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.473 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.472 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.472 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.472 | |
| 1lrh | NLA | Auxin-binding protein 1 | / | 0.472 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.472 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.471 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.471 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.471 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.470 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.470 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.470 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.470 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.469 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.469 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.469 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.469 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.469 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.469 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.468 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.468 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.468 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.468 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.467 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.467 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.467 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.467 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.467 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.466 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.466 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.466 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.466 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.466 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.465 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.465 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.465 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.465 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.465 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.464 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.464 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.464 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.464 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.464 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.463 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.463 | |
| 3pe1 | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.463 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.463 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.463 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.463 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.462 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.462 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.462 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.462 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.462 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.461 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.461 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.461 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.461 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.461 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.461 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.460 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.460 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.460 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.460 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.460 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.460 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.460 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.460 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 4l8u | 9AZ | Serum albumin | / | 0.460 | |
| 4lvg | 20O | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.460 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.460 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.460 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1e7a | PFL | Serum albumin | / | 0.459 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.459 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.459 | |
| 4cjp | 4D2 | Integrase | / | 0.459 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.459 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.458 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.458 | |
| 2xvv | 9DN | Serum albumin | / | 0.458 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.458 | |
| 4ceq | QCH | Integrase | / | 0.458 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.458 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.457 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.457 | |
| 2rto | IMI | Streptavidin | / | 0.457 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.457 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.457 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.457 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.457 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.457 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.457 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.457 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1r2j | FAD | FkbI | / | 0.456 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.456 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.456 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.456 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.456 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.456 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.455 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.455 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.455 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.455 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.455 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.455 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.454 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1jut | LYD | Thymidylate synthase | / | 0.454 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.454 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.454 | |
| 3gb4 | D3M | DdmC | / | 0.454 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 4lb2 | DM5 | Serum albumin | / | 0.454 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.454 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.453 | |
| 2qhw | PZZ | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.453 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.453 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.453 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.453 | |
| 3bhr | THG | Thymidylate synthase | / | 0.453 | |
| 3eks | CY9 | Actin-5C | / | 0.453 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.453 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.453 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.453 | |
| 4cjs | L0Y | Integrase | / | 0.453 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.453 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.453 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.452 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.452 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.452 | |
| 2fai | 459 | Estrogen receptor | / | 0.452 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.452 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.452 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.452 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.452 | |
| 4fv8 | E63 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.452 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.452 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.451 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.451 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.451 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.451 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.451 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.451 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3zw9 | T1G | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.451 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.451 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.451 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.451 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4pd6 | URI | Nucleoside permease | / | 0.451 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.451 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1own | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.450 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.450 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.450 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.450 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.450 | |
| 3up0 | D7S | aceDAF-12 | / | 0.450 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.450 | |
| 4cf2 | 3GM | Integrase | / | 0.450 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.450 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4ogr | ADN | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.450 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.450 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.450 | |
| 5a3b | APR | SIR2 family protein | / | 0.450 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.450 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.449 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.449 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.449 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.449 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3b9l | AZZ | Serum albumin | / | 0.449 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.449 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.449 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.449 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.449 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.449 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.449 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.449 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.449 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.448 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.448 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.448 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.448 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3zuy | TCH | Transporter | / | 0.448 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.448 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4hx5 | 19V | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.448 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.448 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1jqi | CAA | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.447 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.447 | |
| 2bxq | IMN | Serum albumin | / | 0.447 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.447 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.447 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.447 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.447 | |
| 2l84 | J28 | CREB-binding protein | / | 0.447 | |
| 2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.447 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.447 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.447 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.447 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.447 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.447 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.446 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.446 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.446 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.446 | |
| 2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.446 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.446 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.446 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.446 | |
| 4e2b | FMN | Dehydrogenase | / | 0.446 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4inb | 1F6 | Gag protein | / | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4ucn | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.445 | |
| 1fml | RTL | Retinol dehydratase | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.445 | |
| 1osv | CHC | Bile acid receptor | / | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1tys | TMP | Thymidylate synthase | / | 0.445 | |
| 2bxo | OPB | Serum albumin | / | 0.445 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.445 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.445 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.445 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.445 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.445 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.445 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.445 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.445 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.445 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.445 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.445 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.444 | |
| 1syn | F89 | Thymidylate synthase | / | 0.444 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.444 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.444 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.444 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.444 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.444 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.444 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.444 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 4c2p | X8Z | Angiotensin-converting enzyme | 3.2.1 | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.444 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.443 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 1unh | IXM | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.443 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.443 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.443 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.443 | |
| 3dol | GWI | Pol protein | / | 0.443 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3htj | ET | EbrA repressor | / | 0.443 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.443 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.443 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.443 | |
| 4bmp | FMN | Protein NrdI | / | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.443 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.443 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 5gcn | COA | HAT A1 | / | 0.443 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.442 | |
| 1dtp | APU | Diphtheria toxin | / | 0.442 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.442 | |
| 1lke | DOG | Bilin-binding protein | / | 0.442 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.442 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.442 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.442 | |
| 2qvd | BER | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.442 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.442 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.442 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4kfp | 1R7 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.442 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.441 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.441 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.441 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1tdc | UMP | Thymidylate synthase | / | 0.441 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.441 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.441 | |
| 2bxm | IMN | Serum albumin | / | 0.441 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.441 | |
| 3h18 | PMS | Esterase/lipase | / | 0.441 | |
| 3nup | 3NU | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.441 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.441 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.441 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.441 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.441 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.441 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.441 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.441 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.440 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.440 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.440 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.440 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.440 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.440 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.440 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.440 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.440 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 2xwy | IB8 | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2z4w | 749 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.440 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.440 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.440 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.440 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.440 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.440 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.440 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.440 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.440 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.440 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.440 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 |