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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ofm4B0Casein kinase II subunit alpha'2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3ofm4B0Casein kinase II subunit alpha'2.7.11.11.000
3q9xEMOCasein kinase II subunit alpha2.7.11.10.596
4grb0XGCasein kinase II subunit alpha2.7.11.10.592
3at4CCKCasein kinase II subunit alpha2.7.11.10.591
4dgnLU2Casein kinase II subunit alpha2.7.11.10.585
5cvfATPCasein kinase II subunit alpha2.7.11.10.581
3axwTIDCasein kinase II subunit alpha2.7.11.10.574
2pvlP55Casein kinase II subunit alpha2.7.11.10.571
3be9P04Casein kinase II subunit alpha2.7.11.10.571
4anmWULCasein kinase II subunit alpha2.7.11.10.567
4dgmAGICasein kinase II subunit alpha2.7.11.10.564
1m2pHNACasein kinase II subunit alpha2.7.11.10.545
2pvhP19Casein kinase II subunit alpha2.7.11.10.544
3u4uLNHCasein kinase II subunit alpha2.7.11.10.538
3mb714ICasein kinase II subunit alpha2.7.11.10.534
3pe2E1BCasein kinase II subunit alpha2.7.11.10.532
1pjkANPCasein kinase II subunit alpha2.7.11.10.525
1om1IQACasein kinase II subunit alpha2.7.11.10.524
2pvmP29Casein kinase II subunit alpha2.7.11.10.523
2pvjP44Casein kinase II subunit alpha2.7.11.10.493
5av2KMPDeath-associated protein kinase 12.7.11.10.491
4hge15VTyrosine-protein kinase JAK2/0.489
2zjwREFCasein kinase II subunit alpha2.7.11.10.482
5av3KMPDeath-associated protein kinase 12.7.11.10.482
1dayGNPCasein kinase II subunit alpha2.7.11.10.479
2yaaATPDeath-associated protein kinase 2/0.478
2vu3LZECyclin-dependent kinase 22.7.11.220.476
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.474
3rak03ZCyclin-dependent kinase 22.7.11.220.472
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.472
1jklANPDeath-associated protein kinase 12.7.11.10.471
1dawANPCasein kinase II subunit alpha2.7.11.10.470
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.469
4hvi19STyrosine-protein kinase JAK32.7.10.20.469
4jia1K3Tyrosine-protein kinase JAK2/0.469
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.466
3lltANPProtein serine/threonine kinase-1/0.465
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.464
3bqr4RBDeath-associated protein kinase 3/0.463
4aqc88ATyrosine-protein kinase JAK2/0.462
2w17I19Cyclin-dependent kinase 22.7.11.220.461
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.461
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.460
2fvdLIACyclin-dependent kinase 22.7.11.220.459
1m2rMNYCasein kinase II subunit alpha2.7.11.10.458
2vv9IM9Cyclin-dependent kinase 22.7.11.220.458
3lpbNVBTyrosine-protein kinase JAK2/0.458
2pvnP63Casein kinase II subunit alpha2.7.11.10.457
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.455
2w05FRTCyclin-dependent kinase 22.7.11.220.455
4fv9E71Mitogen-activated protein kinase 12.7.11.240.455
1fvv107Cyclin-dependent kinase 22.7.11.220.454
3nux3NVCyclin-dependent kinase 62.7.11.220.454
3rkb12ZCyclin-dependent kinase 22.7.11.220.454
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.454
2uzbC75Cyclin-dependent kinase 22.7.11.220.453
4dgo0JWCasein kinase II subunit alpha2.7.11.10.453
4bcmT7ZCyclin-dependent kinase 22.7.11.220.452
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4ii5ADPCyclin-dependent kinase 22.7.11.220.451
4ez50RSCyclin-dependent kinase 62.7.11.220.450
2pmoHMDProtein kinase 7/0.448
3ezvEZVCyclin-dependent kinase 22.7.11.220.448
3gu7ADPDeath-associated protein kinase 12.7.11.10.448
3qxpX64Cyclin-dependent kinase 22.7.11.220.447
4btjATPTau-tubulin kinase 12.7.11.10.447
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.447
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.445
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.444
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.443
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.442
4aguD15Cyclin-dependent kinase-like 1/0.442
3nynSGVG protein-coupled receptor kinase 62.7.11.160.441
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.440
3i60E86Mitogen-activated protein kinase 12.7.11.240.440
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.440
4i5cC5ITyrosine-protein kinase JAK1/0.440