sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3oez	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3oez	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	1.000
4bkj	STI	Epithelial discoidin domain-containing receptor 1	2.7.10.1	0.522
2pl0	STI	Tyrosine-protein kinase Lck	2.7.10.2	0.467
2rl5	2RL	Vascular endothelial growth factor receptor 2	2.7.10.1	0.462
4equ	G6I	Serine/threonine-protein kinase 10	2.7.11.1	0.457
3b2w	9NH	Tyrosine-protein kinase Lck	2.7.10.2	0.455
5bvw	1N1	Epithelial discoidin domain-containing receptor 1	2.7.10.1	0.443
3rfm	CFF	Adenosine receptor A2a	/	0.441
1x8b	824	Wee1-like protein kinase	2.7.10.2	0.440