sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3oe5	611	Catechol O-methyltransferase	2.1.1.6

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3oe5	611	Catechol O-methyltransferase	2.1.1.6	1.000
3oe4	610	Catechol O-methyltransferase	2.1.1.6	0.698
3r6t	LU1	Catechol O-methyltransferase	2.1.1.6	0.587
3ozt	OZZ	Catechol O-methyltransferase	2.1.1.6	0.580
3ozr	OZR	Catechol O-methyltransferase	2.1.1.6	0.573
3ozs	OZS	Catechol O-methyltransferase	2.1.1.6	0.561
3nw9	637	Catechol O-methyltransferase	2.1.1.6	0.556
3hvk	719	Catechol O-methyltransferase	2.1.1.6	0.541
3hvi	619	Catechol O-methyltransferase	2.1.1.6	0.498
3a7d	FBN	Catechol O-methyltransferase	2.1.1.6	0.490
3nwe	662	Catechol O-methyltransferase	2.1.1.6	0.475
1jr4	CL4	Catechol O-methyltransferase	2.1.1.6	0.473
3nwb	659	Catechol O-methyltransferase	2.1.1.6	0.464
4gbe	SAH	DNA adenine methylase	2.1.1.72	0.459
3a25	SAM	tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase	/	0.450
4rtn	SAH	DNA adenine methylase	2.1.1.72	0.446
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.442