sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 1.000 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.635 | |
| 1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.622 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.614 | |
| 2oa7 | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.609 | |
| 2oad | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.605 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.601 | |
| 3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.597 | |
| 9gss | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.596 | |
| 17gs | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.594 | |
| 2j9h | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.588 | |
| 1aqx | GTD | Glutathione S-transferase P | 2.5.1.18 | 0.583 | |
| 2glr | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.583 | |
| 3csj | CBL | Glutathione S-transferase P | 2.5.1.18 | 0.581 | |
| 2oac | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.575 | |
| 1gti | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.572 | |
| 3n9j | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.561 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.557 | |
| 1pgt | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.536 | |
| 20gs | CBD | Glutathione S-transferase P | 2.5.1.18 | 0.535 | |
| 12gs | 0HH | Glutathione S-transferase P | 2.5.1.18 | 0.509 | |
| 3c1o | NAP | Eugenol synthase | / | 0.502 | |
| 3dgq | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.501 | |
| 4iah | 1DX | Alr2278 protein | / | 0.492 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.488 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.487 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.486 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.486 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.486 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.485 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.485 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.483 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.482 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.482 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.477 | |
| 2ejz | SAH | Diphthine synthase | / | 0.476 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.476 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.476 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.475 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.474 | |
| 3f90 | FMN | Flavodoxin | / | 0.473 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.473 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.472 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.472 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.471 | |
| 1fml | RTL | Retinol dehydratase | / | 0.470 | |
| 2xvw | 9NR | Serum albumin | / | 0.470 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.470 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.470 | |
| 3v2u | ATP | Protein GAL3 | / | 0.470 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.469 | |
| 3e8x | NAP | BH1520 protein | / | 0.469 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.468 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.468 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.468 | |
| 2bxq | IMN | Serum albumin | / | 0.467 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.467 | |
| 4iae | 1DX | Alr2278 protein | / | 0.467 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.466 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.465 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.465 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.465 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.464 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.464 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.464 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.463 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.463 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.463 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.463 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.463 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.462 | |
| 3p9t | TCL | Repressor | / | 0.462 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.462 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.461 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3dzl | 3OC | Phenazine biosynthesis protein A/B | / | 0.461 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.461 | |
| 1uhh | CZP | Aequorin-2 | / | 0.460 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.460 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.460 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.460 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3ghh | 2NF | CD38 molecule | / | 0.459 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.459 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.459 | |
| 4j7h | TRH | PCZA361.3 | / | 0.459 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 1jf0 | CZH | Obelin | / | 0.458 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.458 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.458 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.458 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.458 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.458 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.457 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.457 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.457 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3ny9 | JSZ | Beta-2 adrenergic receptor | / | 0.457 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.456 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.456 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.456 | |
| 3b9l | AZZ | Serum albumin | / | 0.456 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.456 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.456 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.455 | |
| 1qv0 | CZH | Obelin | / | 0.455 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.455 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 4fx9 | COA | Coenzyme A disulfide reductase | 1.8.1.14 | 0.455 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.455 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4n1g | CEI | Obelin | / | 0.454 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.453 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.453 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.453 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.452 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.452 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3nyr | MLC | Putative fatty acid synthase | / | 0.452 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.452 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.452 | |
| 5efw | FMN | NPH1-1 | / | 0.452 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.452 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.451 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.451 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.451 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.450 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.450 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.450 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.450 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3n3a | FMN | Protein NrdI | / | 0.450 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.450 | |
| 3x03 | ANP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.450 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.450 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.450 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.449 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.449 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.449 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.449 | |
| 4nvk | 2NY | Peroxidase | / | 0.449 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.448 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.448 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.448 | |
| 3pft | FMN | Flavin reductase | / | 0.448 | |
| 3pgt | GBX | Glutathione S-transferase P | 2.5.1.18 | 0.448 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.448 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.448 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.448 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.448 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.448 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 1vfs | DCS | Alanine racemase | / | 0.447 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.447 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.447 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.446 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.446 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.446 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.445 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.445 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2bxm | IMN | Serum albumin | / | 0.445 | |
| 2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 2po3 | T4K | 4-dehydrase | / | 0.445 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.445 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3ele | PLP | Aminotransferase | / | 0.445 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.445 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.445 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.444 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.444 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.444 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.444 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.444 | |
| 4ai8 | DZA | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.444 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.444 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.444 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.444 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1mtc | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.443 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.443 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.443 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.443 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.443 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.443 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.443 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1h8h | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 1h8h | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.442 | |
| 2v7q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2vuu | NAP | Nitrogen metabolite repression protein nmrA | / | 0.442 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.442 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.442 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.442 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.442 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.441 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.441 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.441 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.441 | |
| 3h0w | N8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.441 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.441 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.441 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.441 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.441 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1g28 | FMN | PHY3 | / | 0.440 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.440 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.440 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.440 | |
| 1w29 | TS0 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.440 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.440 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.440 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.440 | |
| 4e2y | JHZ | Methyltransferase | / | 0.440 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.440 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.440 |