Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 1.000 | |
2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.645 | |
2y71 | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.607 | |
2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.605 | |
2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.599 | |
2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.594 | |
2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.585 | |
4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.576 | |
2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.541 | |
4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.528 | |
3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.523 | |
4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.518 | |
4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.515 | |
1el4 | CTZ | Obelin | / | 0.502 | |
4g8j | THM | Uridine phosphorylase | / | 0.502 | |
1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.499 | |
4p9d | TMP | Deoxycytidylate deaminase | / | 0.499 | |
2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.497 | |
3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.496 | |
3sl2 | ATP | Sensor histidine kinase WalK | / | 0.496 | |
1jdz | FMB | Purine nucleoside phosphorylase | / | 0.495 | |
3v2u | ATP | Protein GAL3 | / | 0.495 | |
4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.495 | |
4l0o | PLP | Cystathionine gamma-synthase | 2.5.1.48 | 0.494 | |
4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.494 | |
1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.493 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.493 | |
1txt | CAA | HMG-CoA synthase | / | 0.491 | |
1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.491 | |
2ejz | SAH | Diphthine synthase | / | 0.491 | |
4fhd | 0TT | Spore photoproduct lyase | / | 0.491 | |
5dp2 | NAP | CurF | / | 0.490 | |
1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
3q8u | ADP | Nucleoside diphosphate kinase | / | 0.489 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.488 | |
1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.488 | |
2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.488 | |
2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.488 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.488 | |
5c1g | GDU | Histo-blood group ABO system transferase | / | 0.488 | |
1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.487 | |
2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.487 | |
3v0n | 4GW | Histo-blood group ABO system transferase | / | 0.487 | |
4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.487 | |
1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.486 | |
1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.485 | |
1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.485 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.485 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.485 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.485 | |
4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.485 | |
5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.485 | |
1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.483 | |
2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.483 | |
1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.482 | |
4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.482 | |
3bk2 | U5P | Ribonuclease J | / | 0.481 | |
3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.481 | |
3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.480 | |
4n1g | CEI | Obelin | / | 0.480 | |
2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.479 | |
2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.479 | |
3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.479 | |
4isg | 1FY | Glucokinase | 2.7.1.2 | 0.479 | |
1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.478 | |
2dxv | SAH | Diphthine synthase | / | 0.478 | |
2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.478 | |
4ise | 1FW | Glucokinase | 2.7.1.2 | 0.478 | |
1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.477 | |
2e1z | B4P | Propionate kinase | / | 0.477 | |
3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.477 | |
4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.477 | |
4qzu | RTL | Retinol-binding protein 2 | / | 0.477 | |
1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.476 | |
2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.476 | |
3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.476 | |
3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.476 | |
1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.475 | |
2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
2gl0 | ADN | Uncharacterized protein | / | 0.475 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.475 | |
4bb2 | STR | Corticosteroid-binding globulin | / | 0.475 | |
4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.475 | |
2c97 | JCL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.474 | |
3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.474 | |
4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.474 | |
1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.473 | |
4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.472 | |
2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.472 | |
2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.472 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
3i97 | 8DR | Neuropilin-1 | / | 0.472 | |
4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
4imf | SI3 | N-acetylneuraminate lyase | / | 0.472 | |
4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
4jzr | 4JR | Egl nine homolog 1 | / | 0.472 | |
4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.472 | |
1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.471 | |
1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.471 | |
1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.471 | |
1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.471 | |
1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.471 | |
3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.471 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.471 | |
4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.471 | |
1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.470 | |
2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.470 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.470 | |
3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.470 | |
4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.470 | |
4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.470 | |
5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.470 | |
1j0d | 5PA | 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.469 | |
1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.469 | |
2clf | F6F | Tryptophan synthase alpha chain | / | 0.469 | |
3djf | BC3 | Purine nucleoside phosphorylase | / | 0.469 | |
3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.469 | |
4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.469 | |
1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.468 | |
2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.468 | |
2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.468 | |
3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.468 | |
3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
4rel | KMP | Glycosyltransferase | / | 0.468 | |
4rh1 | 0TT | Spore photoproduct lyase | / | 0.468 | |
1srj | NAB | Streptavidin | / | 0.467 | |
1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.467 | |
2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.467 | |
2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.467 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.467 | |
4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.467 | |
4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.467 | |
1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.466 | |
1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.466 | |
1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.466 | |
2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.466 | |
3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.466 | |
4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
4oma | LCS | Methionine gamma-lyase | / | 0.466 | |
4uof | DAT | Nucleoside diphosphate kinase | / | 0.466 | |
2eh5 | SAH | Diphthine synthase | / | 0.465 | |
3nx2 | FER | Ferulic acid decarboxylase | / | 0.465 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
3opx | U5P | Suppressor of disruption of TFIIS | / | 0.465 | |
1jf2 | CZH | Obelin | / | 0.464 | |
1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.464 | |
1w29 | TS0 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
2g1r | 3IG | Renin | 3.4.23.15 | 0.464 | |
2hr8 | SAH | Diphthine synthase | / | 0.464 | |
2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.464 | |
2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.464 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.464 | |
3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.464 | |
3m53 | SAH | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.464 | |
3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.464 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.464 | |
4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.464 | |
4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.464 | |
1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.463 | |
1x1c | SAH | C-20 methyltransferase | / | 0.463 | |
2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.463 | |
3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.463 | |
3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
3e6e | DCS | Alanine racemase | / | 0.463 | |
3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.463 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
4lzw | THM | Uridine phosphorylase | / | 0.463 | |
5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.463 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.463 | |
1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
2clm | F6F | Tryptophan synthase alpha chain | / | 0.462 | |
2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.462 | |
2h4k | 509 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.462 | |
2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.462 | |
2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.462 | |
3e8x | NAP | BH1520 protein | / | 0.462 | |
3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.462 | |
3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.462 | |
4fhf | 0TT | Spore photoproduct lyase | / | 0.462 | |
4guk | P2G | Neuronal calcium sensor 1 | / | 0.462 | |
4j0z | 1H5 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.461 | |
1jdt | MTA | Purine nucleoside phosphorylase | / | 0.461 | |
1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
1thn | ADP | Anti-sigma F factor | / | 0.461 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.461 | |
2dxe | GDP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.461 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.461 | |
2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.461 | |
3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.461 | |
3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.461 | |
4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.461 | |
4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.461 | |
4prx | ADP | DNA gyrase subunit B | / | 0.461 | |
1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.460 | |
1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
1mxf | MTX | Putative pteridine reductase 2 | / | 0.460 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
1xdd | AAY | Integrin alpha-L | / | 0.460 | |
2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.460 | |
3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.460 | |
4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.460 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
4h9t | HL4 | Phosphotriesterase | / | 0.460 | |
4nqg | CZH | Mitrocomin | / | 0.460 | |
4wud | ANP | DNA gyrase subunit B | / | 0.460 | |
1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.459 | |
1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.459 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.459 | |
1vfs | DCS | Alanine racemase | / | 0.459 | |
2eh4 | SAH | Diphthine synthase | / | 0.459 | |
2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.459 | |
3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.459 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.459 | |
4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.459 | |
1c7o | PPG | Hemolysin | / | 0.458 | |
1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.458 | |
1fmj | RTL | Retinol dehydratase | / | 0.458 | |
1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.458 | |
1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.458 | |
1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
1xjq | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.458 | |
1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.458 | |
2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.458 | |
2egl | SAH | Diphthine synthase | / | 0.458 | |
2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.458 | |
3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.458 | |
3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
3x2f | NAI | Adenosylhomocysteinase | / | 0.458 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.457 | |
2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.457 | |
2cle | F6F | Tryptophan synthase alpha chain | / | 0.457 | |
2e08 | SAH | Diphthine synthase | / | 0.457 | |
2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.457 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.457 | |
2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.457 | |
2yhu | WHF | Pteridine reductase | / | 0.457 | |
2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.457 | |
3eps | ATP | Isocitrate dehydrogenase kinase/phosphatase | / | 0.457 | |
3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.457 | |
1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.456 | |
1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.456 | |
1waj | 5GP | DNA-directed DNA polymerase | / | 0.456 | |
2dsg | SAH | Diphthine synthase | / | 0.456 | |
2g1s | 4IG | Renin | 3.4.23.15 | 0.456 | |
2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.456 | |
2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.456 | |
3b1d | PLS | BetaC-S lyase | / | 0.456 | |
3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.456 | |
3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.456 | |
3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.456 | |
3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.456 | |
3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.456 | |
4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
4kby | C2E | Stimulator of interferon genes protein | / | 0.456 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
4pl9 | ADP | Ethylene receptor 1 | / | 0.456 | |
4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.456 | |
5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.456 | |
1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.455 | |
1je1 | GMP | Purine nucleoside phosphorylase | / | 0.455 | |
1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
2bsx | NOS | Purine nucleoside phosphorylase | / | 0.455 | |
2fxu | BID | Actin, alpha skeletal muscle | / | 0.455 | |
2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.455 | |
2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.455 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.455 | |
3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.455 | |
3kt8 | LTN | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.455 | |
3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
4f3g | KAI | Glutamate receptor 3 | / | 0.455 | |
4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
4y9u | NAP | NADPH--cytochrome P450 reductase | / | 0.455 | |
1f4e | TPR | Thymidylate synthase | / | 0.454 | |
1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.454 | |
2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.454 | |
3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
3lcj | COA | Phosphopantetheine adenylyltransferase | / | 0.454 | |
3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.454 | |
4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.454 | |
5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.454 | |
1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.453 | |
1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.453 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.453 | |
2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.453 | |
2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.453 | |
3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.453 | |
4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.452 | |
1k8y | 13P | Tryptophan synthase alpha chain | / | 0.452 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
1qzy | TDE | Methionine aminopeptidase 2 | / | 0.452 | |
1s36 | CEI | Obelin | / | 0.452 | |
2c20 | NAD | UDP-glucose 4-epimerase | / | 0.452 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
2emu | SAH | Diphthine synthase | / | 0.452 | |
2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.452 | |
2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.452 | |
3b9l | AZZ | Serum albumin | / | 0.452 | |
3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.452 | |
3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.452 | |
3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.452 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.452 | |
5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.452 | |
1a69 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.451 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
1z41 | FMN | NADPH dehydrogenase | / | 0.451 | |
2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.451 | |
2vfz | UPF | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.451 | |
2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.451 | |
3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.451 | |
3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.451 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
3v49 | PK0 | Androgen receptor | / | 0.451 | |
4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.451 | |
4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.451 | |
4bam | MM9 | Prothrombin | 3.4.21.5 | 0.451 | |
4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.451 | |
4fqs | LYA | Thymidylate synthase ThyA | / | 0.451 | |
4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
4qai | FMN | NADPH dehydrogenase | / | 0.451 | |
4uoh | ADP | Nucleoside diphosphate kinase | / | 0.451 | |
4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
4zas | TYD | CalS13 | / | 0.451 | |
5c4n | NAP | Precorrin-6A reductase | 1.3.1.54 | 0.451 | |
5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.451 | |
1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.450 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
2e8h | SAH | Diphthine synthase | / | 0.450 | |
2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.450 | |
2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.450 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.450 | |
2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.450 | |
3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.450 | |
3i0p | NAD | Malate dehydrogenase, putative | / | 0.450 | |
3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.450 | |
4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.450 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
1wop | FFO | Aminomethyltransferase | / | 0.449 | |
1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
2ek7 | SAH | Diphthine synthase | / | 0.449 | |
3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.449 | |
3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
3in6 | FMN | Uncharacterized protein | / | 0.449 | |
3nt5 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.449 | |
3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.449 | |
3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.449 | |
4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.449 | |
4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
4cmf | PXG | Uncharacterized protein | / | 0.449 | |
4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.449 | |
4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.449 | |
5d7o | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.449 | |
1ndc | TYD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.448 | |
1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.448 | |
1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.448 | |
1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.448 | |
2jgs | BTN | Avidin | / | 0.448 | |
2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.448 | |
3cne | FMN | Putative protease I | / | 0.448 | |
3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.448 | |
3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.448 | |
3t74 | UBY | Thermolysin | 3.4.24.27 | 0.448 | |
4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.448 | |
4umy | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
4uoc | NCN | CinA-like protein | / | 0.448 | |
1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.447 | |
1lbb | KAI | Glutamate receptor 2 | / | 0.447 | |
1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.447 | |
1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.447 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
1xag | NAD | 3-dehydroquinate synthase | / | 0.447 | |
1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.447 | |
2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.447 | |
3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.447 | |
3hdy | GDU | UDP-galactopyranose mutase | / | 0.447 | |
4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.447 | |
4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
4f9a | ADP | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.447 | |
4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
4pzs | ACO | Histone acetyltransferase p300 | / | 0.447 | |
4tln | LNO | Thermolysin | 3.4.24.27 | 0.447 | |
4y9r | NAP | NADPH--cytochrome P450 reductase | / | 0.447 | |
5fdg | 0N8 | Polymerase acidic protein | / | 0.447 | |
1b87 | ACO | Aac(6')-Ii protein | / | 0.446 | |
1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
1qv0 | CZH | Obelin | / | 0.446 | |
1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.446 | |
1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.446 | |
2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.446 | |
2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.446 | |
2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.446 | |
3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.446 | |
3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
3smk | CW7 | 14-3-3 protein sigma | / | 0.446 | |
4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
4wrk | DUP | DUTPase | / | 0.446 | |
4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
2ycx | P32 | Beta-1 adrenergic receptor | / | 0.446 | |
1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
1o69 | X04 | Aminotransferase DegT | / | 0.445 | |
1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.445 | |
1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.445 | |
1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.445 | |
1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
2dv3 | SAH | Diphthine synthase | / | 0.445 | |
2dv7 | SAH | Diphthine synthase | / | 0.445 | |
2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.445 | |
3arv | SAU | Chitinase A | / | 0.445 | |
3bg7 | FAD | Pyranose 2-oxidase | / | 0.445 | |
3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
3gc5 | 2MQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
3pn1 | IVH | DNA ligase | / | 0.445 | |
3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.445 | |
3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.445 | |
3rt4 | LP5 | Peptidoglycan recognition protein 1 | / | 0.445 | |
3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.445 | |
4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.445 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.445 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.445 | |
12gs | 0HH | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.444 | |
1fw0 | KAI | Glutamate receptor 2 | / | 0.444 | |
1jtq | LY3 | Thymidylate synthase | / | 0.444 | |
1lnm | DTX | Bilin-binding protein | / | 0.444 | |
1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.444 | |
1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
1wng | SAH | Diphthine synthase | / | 0.444 | |
2dv4 | SAH | Diphthine synthase | / | 0.444 | |
2ed3 | SAH | Diphthine synthase | / | 0.444 | |
2el0 | SAH | Diphthine synthase | / | 0.444 | |
2eni | SAH | Diphthine synthase | / | 0.444 | |
2iku | LIY | Renin | 3.4.23.15 | 0.444 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
2pb4 | SAH | Diphthine synthase | / | 0.444 | |
2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.444 | |
3cvk | N34 | Genome polyprotein | 2.7.7.48 | 0.444 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.444 | |
3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.444 | |
3n0y | APC | Adenylate cyclase 2 | / | 0.444 | |
3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 0.444 | |
3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
4aza | MGO | Eukaryotic translation initiation factor 4E | / | 0.444 | |
4b4w | 9L9 | Bifunctional protein FolD | / | 0.444 | |
4d7m | TDC | Tetracycline repressor protein class D | / | 0.444 | |
4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.444 | |
4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.444 | |
4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
4wxf | PLG | Serine hydroxymethyltransferase | / | 0.444 | |
4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
1jf0 | CZH | Obelin | / | 0.443 | |
1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.443 | |
1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.443 | |
2emr | SAH | Diphthine synthase | / | 0.443 | |
2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.443 | |
2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.443 | |
2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.443 | |
2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
2pcm | SAH | Diphthine synthase | / | 0.443 | |
2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.443 | |
2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.443 | |
2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.443 | |
3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.443 | |
3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.443 | |
3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.443 | |
4iom | FOL | Formate--tetrahydrofolate ligase | / | 0.443 | |
4qt3 | RAP | Peptidylprolyl isomerase | / | 0.443 | |
4rgq | NDP | Glycerol-1-phosphate dehydrogenase [NAD(P)+] | / | 0.443 | |
4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.443 | |
4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.443 | |
5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.443 | |
5kf8 | ACO | Predicted acetyltransferase | / | 0.443 | |
1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.442 | |
2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.442 | |
2du2 | FMN | Lactate oxidase | / | 0.442 | |
2e4n | SAH | Diphthine synthase | / | 0.442 | |
2fq6 | P3F | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.442 | |
2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.442 | |
2nr4 | FMN | Conserved protein | / | 0.442 | |
2oad | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.442 | |
2owg | SAH | Diphthine synthase | / | 0.442 | |
2r8p | T6F | Transketolase 1 | / | 0.442 | |
3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.442 | |
3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.442 | |
3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.442 | |
3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
3up0 | D7S | aceDAF-12 | / | 0.442 | |
4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.442 | |
4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
4dne | DTB | Streptavidin | / | 0.442 | |
4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.442 | |
4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
4yfy | 1YJ | VioF | / | 0.442 | |
5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.442 | |
5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
1cjw | COT | Serotonin N-acetyltransferase | / | 0.441 | |
1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.441 | |
1k8z | IAG | Tryptophan synthase alpha chain | / | 0.441 | |
1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.441 | |
1uhj | CZB | Aequorin-2 | / | 0.441 | |
1xuz | MMN | Capsule biosynthesis protein | / | 0.441 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.441 | |
2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
2dzb | HH2 | Dihydropteroate synthase | / | 0.441 | |
2e07 | SAH | Diphthine synthase | / | 0.441 | |
2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.441 | |
2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.441 | |
2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.441 | |
3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.441 | |
3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.441 | |
3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
3ry2 | BTN | Streptavidin | / | 0.441 | |
3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
3vhx | GTP | ADP-ribosylation factor 6 | / | 0.441 | |
3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.441 | |
4du6 | GTP | GTP cyclohydrolase 1 | / | 0.441 | |
4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.441 | |
4hfp | 15U | Prothrombin | 3.4.21.5 | 0.441 | |
4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
4zqc | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
1j8q | FMN | Flavodoxin | / | 0.440 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.440 | |
2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.440 | |
2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.440 | |
2oaz | I96 | Methionine aminopeptidase 2 | / | 0.440 | |
2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.440 | |
2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.440 | |
3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.440 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.440 | |
4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
4ap1 | NAP | Steroid monooxygenase | / | 0.440 | |
4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
4n1f | CZH | Obelin | / | 0.440 | |
4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 |