scPDB - Distribution of Cavity Similarity values of 3n65 entry / Site 2

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	1.000
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.645
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.629
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.629
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.621
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.615
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.612
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.611
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.602
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.591
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.583
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.583
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.582
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.572
4imu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.567
3ufs	H4B	Nitric oxide synthase, brain	1.14.13.39	0.565
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.559
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.555
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.547
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.547
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.542
3n61	H4B	Nitric oxide synthase, brain	1.14.13.39	0.538
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.538
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.534
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.531
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.525
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.524
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.523
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.523
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.520
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.518
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.517
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.514
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.511
3ufp	H4W	Nitric oxide synthase, brain	1.14.13.39	0.511
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.510
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.508
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.507
3rql	H4B	Nitric oxide synthase, brain	1.14.13.39	0.504
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.504
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.504
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.503
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.497
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.495
3tym	H4B	Nitric oxide synthase, brain	1.14.13.39	0.491
3ufw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.491
3jx6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.490
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.488
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.486
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.486
3ufp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.483
1zzq	DP9	Nitric oxide synthase, brain	1.14.13.39	0.482
3svp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.482
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.481
4cx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.481
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.480
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.480
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.479
3rqk	X2C	Nitric oxide synthase, brain	1.14.13.39	0.478
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.476
4k5d	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.473
3uft	H4B	Nitric oxide synthase, brain	1.14.13.39	0.472
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.471
1zzq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.469
3n5z	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.467
4gqe	H4B	Nitric oxide synthase, brain	1.14.13.39	0.467
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.466
3uft	HW7	Nitric oxide synthase, brain	1.14.13.39	0.466
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.463
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.463
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.462
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.461
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.460
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.460
4imw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.459
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.457
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
3jt4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3jt6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.453
3nlq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.453
4k5e	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3b3p	JI7	Nitric oxide synthase, brain	1.14.13.39	0.451
3jt3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.451
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.450
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
1p6k	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
3b3m	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
3ufo	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
2hx4	4HX	Nitric oxide synthase, brain	1.14.13.39	0.446
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.446
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.446
4k5d	1Q6	Nitric oxide synthase, brain	1.14.13.39	0.445
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.444
3q99	H4B	Nitric oxide synthase, brain	1.14.13.39	0.444
4jsg	H4B	Nitric oxide synthase, brain	1.14.13.39	0.444
1m00	H4B	Nitric oxide synthase, brain	1.14.13.39	0.443
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.442
4fw0	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.440