sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.932 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.886 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.864 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.860 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.851 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.843 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.825 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.805 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.803 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.801 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.790 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.785 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.784 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.773 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.749 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.734 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.699 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.616 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.609 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.587 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.584 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.575 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.574 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.564 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.552 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.546 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.536 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.530 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.522 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.515 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.515 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.514 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.512 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.511 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.505 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.500 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.494 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.489 | |
| 4iae | 1DX | Alr2278 protein | / | 0.488 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.484 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.481 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.478 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.477 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.475 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.473 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.472 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.472 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.472 | |
| 4iah | 1DX | Alr2278 protein | / | 0.472 | |
| 4jic | FMN | GTN Reductase | / | 0.472 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.471 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.471 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.471 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.470 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.470 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.467 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.466 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.466 | |
| 4rel | KMP | Glycosyltransferase | / | 0.466 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.465 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.464 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.464 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.463 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.461 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.460 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.459 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.458 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.458 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.457 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.457 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.457 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.457 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.456 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.456 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.456 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.454 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.453 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.453 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.453 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.452 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.452 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.452 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.451 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.451 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.451 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.451 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.450 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.450 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.450 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.449 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.449 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.449 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.449 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.449 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.448 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.448 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.448 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.448 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.448 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.448 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.447 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4y1b | NAP | AntE | / | 0.447 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.446 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.446 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.446 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.446 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.446 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.446 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.446 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.445 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.445 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.445 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.445 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.444 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.444 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.444 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.444 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.444 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.443 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 3eks | CY9 | Actin-5C | / | 0.443 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.443 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.442 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.442 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.442 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.441 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.441 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.440 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.440 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.440 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.440 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.440 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3vp6 | HLD | Glutamate decarboxylase 1 | 4.1.1.15 | 0.440 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4e2b | FMN | Dehydrogenase | / | 0.440 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.440 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.440 |