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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3mqe416Prostaglandin G/H synthase 21.14.99.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3mqe416Prostaglandin G/H synthase 21.14.99.11.000
3ln1CELProstaglandin G/H synthase 21.14.99.10.558
3rr3FLRProstaglandin G/H synthase 21.14.99.10.552
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.523
4otyLURProstaglandin G/H synthase 21.14.99.10.498
4coxIMNProstaglandin G/H synthase 21.14.99.10.494
5ikrID8Prostaglandin G/H synthase 21.14.99.10.489
3ntgD72Prostaglandin G/H synthase 21.14.99.10.478
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.460
2oyuIMSProstaglandin G/H synthase 11.14.99.10.454
4rrxLURProstaglandin G/H synthase 21.14.99.10.453
3q7dNPXProstaglandin G/H synthase 21.14.99.10.449
4rrwLURProstaglandin G/H synthase 21.14.99.10.449
4rrzLURProstaglandin G/H synthase 21.14.99.10.449