sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3mfu	ANP	Peripheral plasma membrane protein CASK	2.7.11.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3mfu	ANP	Peripheral plasma membrane protein CASK	2.7.11.1	1.000
3mfs	ANP	Peripheral plasma membrane protein CASK	2.7.11.1	0.674
3mfr	ANP	Peripheral plasma membrane protein CASK	2.7.11.1	0.656
3c0i	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.468
3wow	ANP	Casein kinase II subunit alpha	2.7.11.1	0.461
2vz6	FEF	Calcium/calmodulin-dependent protein kinase type II subunit alpha	2.7.11.17	0.451
3v8w	0G2	Tyrosine-protein kinase ITK/TSK	2.7.10.2	0.450
2vu3	LZE	Cyclin-dependent kinase 2	2.7.11.22	0.449
1q97	ATP	Serine/threonine-protein kinase SKY1	2.7.11.1	0.443