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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3mfsANPPeripheral plasma membrane protein CASK2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3mfsANPPeripheral plasma membrane protein CASK2.7.11.11.000
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.618
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.563
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.486
2w05FRTCyclin-dependent kinase 22.7.11.220.462
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.452