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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3megT27Gag-Pol polyprotein2.7.7.49

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3megT27Gag-Pol polyprotein2.7.7.491.000
3mec65BGag-Pol polyprotein2.7.7.490.650
3meeT27Gag-Pol polyprotein2.7.7.490.632
2rf2MRXGag-Pol polyprotein2.7.7.490.631
3m8qDJZGag-Pol polyprotein2.7.7.490.622
3med65BGag-Pol polyprotein2.7.7.490.605
1ikxPNUGag-Pol polyprotein2.7.7.490.595
1ikvEFZGag-Pol polyprotein2.7.7.490.586
1ikwEFZGag-Pol polyprotein2.7.7.490.584
2vg7NNIGag-Pol polyprotein2.7.7.490.575
4i7fNVEGag-Pol polyprotein2.7.7.490.568
1tl1H18Gag-Pol polyprotein2.7.7.490.561
1rt4UC1Gag-Pol polyprotein2.7.7.490.555
2hnzPC0Gag-Pol polyprotein2.7.7.490.554
1c1bGCAGag-Pol polyprotein2.7.7.490.552
1revTB9Gag-Pol polyprotein2.7.7.490.552
1s1wUC1Gag-Pol polyprotein2.7.7.490.551
3qlhT27Gag-Pol polyprotein2.7.7.490.549
3i0rRT3Gag-Pol polyprotein2.7.7.490.546
1eetBFUGag-Pol polyprotein2.7.7.490.540
1tl3H20Gag-Pol polyprotein2.7.7.490.540
1fk9EFZGag-Pol polyprotein2.7.7.490.538
2ze2T27Gag-Pol polyprotein2.7.7.490.537
3i0sRT7Gag-Pol polyprotein2.7.7.490.537
4i2pG73Gag-Pol polyprotein2.7.7.490.537
1tkzH16Gag-Pol polyprotein2.7.7.490.535
1tktH12Gag-Pol polyprotein2.7.7.490.528
3m8p65BGag-Pol polyprotein2.7.7.490.528
1s6qTPBGag-Pol polyprotein2.7.7.490.526
1s9eADBGag-Pol polyprotein2.7.7.490.524
3ffi3OBGag-Pol polyprotein2.7.7.490.523
4id5T27Gag-Pol polyprotein2.7.7.490.520
1hnvTBOGag-Pol polyprotein2.7.7.490.517
4i2q1BTGag-Pol polyprotein2.7.7.490.517
1ikyMSDGag-Pol polyprotein2.7.7.490.515
1vruAAPGag-Pol polyprotein2.7.7.490.514
4kko1REGag-Pol polyprotein2.7.7.490.512
2opqHBQGag-Pol polyprotein2.7.7.490.511
2zd1T27Gag-Pol polyprotein2.7.7.490.511
1osvCHCBile acid receptor/0.509
4g1qT27Gag-Pol polyprotein2.7.7.490.509
3is9AC7Gag-Pol polyprotein2.7.7.490.507
1rt2TNKGag-Pol polyprotein2.7.7.490.506
1hpzAAPGag-Pol polyprotein2.7.7.490.502
1xddAAYIntegrin alpha-L/0.502
4b4oNDPEpimerase family protein SDR39U1/0.502
4ifvT27Gag-Pol polyprotein2.7.7.490.501
4ko0JLJGag-Pol polyprotein2.7.7.490.501
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.499
1rt5UC2Gag-Pol polyprotein2.7.7.490.495
4ig3T27Gag-Pol polyprotein2.7.7.490.495
2hndNVPGag-Pol polyprotein2.7.7.490.494
1jlgUC1Gag-Pol polyprotein2.7.7.490.487
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.487
4inb1F6Gag protein/0.484
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.483
1hquHBYGag-Pol polyprotein2.7.7.490.483
1v7aFRCAdenosine deaminase3.5.4.40.482
3bfa9ODOdorant binding protein ASP1/0.482
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.480
2vg5NNCGag-Pol polyprotein2.7.7.490.479
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.479
5uviZMAAdenosine receptor A2a/0.479
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
1jlcFTCGag-Pol polyprotein2.7.7.490.477
2qd5CHDFerrochelatase, mitochondrial4.99.1.10.477
2znnS44Peroxisome proliferator-activated receptor alpha/0.477
4eevL1XHepatocyte growth factor receptor2.7.10.10.476
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.474
1n4hREANuclear receptor ROR-beta/0.473
1ndeMONEstrogen receptor beta/0.473
1ot7CHCBile acid receptor/0.473
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
1ep4S11Gag-Pol polyprotein2.7.7.490.472
3nwyGTPUridylate kinase/0.472
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
1zhzERGOxysterol-binding protein homolog 4/0.471
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
4dbzNDPPutative ketoacyl reductase1.3.10.471
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.470
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.469
4j6bPLOCytochrome P450 monooxygenase/0.469
4lxhC1EAlpha/beta hydrolase fold/0.469
1klmSPPGag-Pol polyprotein2.7.7.490.468
3bfb9ODPheromone-binding protein ASP1/0.468
3ictADPCoenzyme A disulfide reductase/0.468
3irxUDRGag-Pol polyprotein2.7.7.490.468
2zbaZBATrichothecene 3-O-acetyltransferase/0.467
3s1dZIRCytokinin dehydrogenase 11.5.99.120.467
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.466
3l9hEMQKinesin-like protein KIF11/0.466
5k2aZMAAdenosine receptor A2a/0.466
3cd2MTXDihydrofolate reductase1.5.1.30.465
3lamKRPGag-Pol polyprotein2.7.7.490.465
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.465
1ezvSMACytochrome b/0.464
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
3lanKBTGag-Pol polyprotein2.7.7.490.464
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4qe6JN3Bile acid receptor/0.464
4ubsDIFPentalenic acid synthase1.14.15.110.464
1hniAAAGag-Pol polyprotein2.7.7.490.463
1yinCM3Estrogen receptor/0.463
2vzmNRBCytochrome P450 monooxygenase PikC/0.463
3a60STURibosomal protein S6 kinase beta-12.7.11.10.463
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
2jn3JN3Fatty acid-binding protein, liver/0.462
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.462
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.462
3h0a9RARetinoic acid receptor RXR-alpha/0.462
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.462
3pe6ZYHMonoglyceride lipase/0.462
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.462
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2y00Y01Beta-1 adrenergic receptor/0.461
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1lriCLRBeta-elicitin cryptogein/0.460
1xuoLA1Integrin alpha-L/0.460
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.460
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.460
4kwi1TJReductase homolog/0.460
4q73FADBifunctional protein PutA/0.460
5hi2BAXSerine/threonine-protein kinase B-raf2.7.11.10.460
1kb9SMACytochrome b/0.459
2ibzSMACytochrome b/0.459
3dl9V2HVitamin D 25-hydroxylase/0.459
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.459
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.459
4e37NDPCatalase1.11.1.60.459
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.459
5l7dCLRSmoothened homolog/0.459
5k2bZMAAdenosine receptor A2a/0.459
1fm4DXCMajor pollen allergen Bet v 1-L/0.458
1zhwHC2Oxysterol-binding protein homolog 4/0.458
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
3hx4ANPCalmodulin-domain protein kinase 1/0.458
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.458
4rrwLURProstaglandin G/H synthase 21.14.99.10.458
4rrzLURProstaglandin G/H synthase 21.14.99.10.458
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.457
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
1ml6GBXGlutathione S-transferase A22.5.1.180.457
3gc9B45Mitogen-activated protein kinase 112.7.11.240.457
3gwfFADCyclohexanone monooxygenase/0.457
3icrCOACoenzyme A disulfide reductase/0.457
3vtdTKDVitamin D3 receptor/0.457
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
4xldBRLPeroxisome proliferator-activated receptor gamma/0.457
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.456
1o5rFR9Adenosine deaminase3.5.4.40.456
1uzwCDHIsopenicillin N synthase1.21.3.10.456
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.456
2bx8AZQSerum albumin/0.456
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
3mdvCL6Cholesterol 24-hydroxylase/0.456
3nalDBKCalcium-transporting ATPase/0.456
3oibFDAPutative acyl-CoA dehydrogenase/0.456
4cd2FOLDihydrofolate reductase1.5.1.30.456
4ez8DHFThymidylate synthase2.1.1.450.456
1l2jETCEstrogen receptor beta/0.455
1nq7ARLNuclear receptor ROR-beta/0.455
1w06W05Isopenicillin N synthase1.21.3.10.455
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2ydoADNAdenosine receptor A2a/0.455
2z3uCRRCytochrome P450/0.455
3lfcZ86Mitogen-activated protein kinase 14/0.455
3lu8IQXSerum albumin/0.455
3qlsNDPDihydrofolate reductase1.5.1.30.455
3srqQ19Dihydrofolate reductase1.5.1.30.455
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4q72FADBifunctional protein PutA/0.455
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
5k2cZMAAdenosine receptor A2a/0.455
1kzjCB3Thymidylate synthase/0.454
1sr7MOFProgesterone receptor/0.454
1tkxGWBGag-Pol polyprotein2.7.7.490.454
2q61SF1Peroxisome proliferator-activated receptor gamma/0.454
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.454
3juhANPCasein kinase II subunit alpha2.7.11.10.454
3own3OWRenin3.4.23.150.454
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.454
4dc0NDPPutative ketoacyl reductase1.3.10.454
4g1y0VOVitamin D3 receptor A/0.454
4j6cSTRCytochrome P450 monooxygenase/0.454
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.454
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.454
5jtbZMAAdenosine receptor A2a/0.454
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
1ie8KH1Vitamin D3 receptor/0.453
1rdtL79Retinoic acid receptor RXR-alpha/0.453
1tvrTB9Gag-Pol polyprotein2.7.7.490.453
2ban357Gag-Pol polyprotein2.7.7.490.453
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.453
2o3zAI7UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.453
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.453
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
3tubFPUTyrosine-protein kinase SYK2.7.10.20.453
4gk2L66Ephrin type-A receptor 32.7.10.10.453
4klrCHDFerrochelatase, mitochondrial4.99.1.10.453
5iu4ZMAAdenosine receptor A2a/0.453
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1pp9SMACytochrome b/0.452
1sj0E4DEstrogen receptor/0.452
2aibERGBeta-elicitin cinnamomin/0.452
2c7xNRBCytochrome P450 monooxygenase PikC/0.452
4b1fKRHGlutamate racemase/0.452
4gmy0X5Tyrosine-protein kinase JAK2/0.452
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.452
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1jipKTN6-deoxyerythronolide B hydroxylase/0.451
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.451
1y4lSVRBasic phospholipase A2 homolog 2/0.451
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.451
2vn0TDZCytochrome P450 2C8/0.451
2z7gEH9Adenosine deaminase3.5.4.40.451
3frqERYErythromycin resistance repressor protein/0.451
3ictCOACoenzyme A disulfide reductase/0.451
3l0lHC3Nuclear receptor ROR-gamma/0.451
3qqkX02Cyclin-dependent kinase 22.7.11.220.451
4b7dQLECytochrome P450 monooxygenase PikC/0.451
4b7sQLECytochrome P450 monooxygenase PikC/0.451
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.451
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.451
4fkv61KCyclin-dependent kinase 22.7.11.220.451
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.451
4iaq2GM5-hydroxytryptamine receptor 1B/0.451
4nb6444Nuclear receptor ROR-gamma/0.451
5iua6DXAdenosine receptor A2a/0.451
3emlZMAAdenosine receptor A2a/0.451
1ly3COGDihydrofolate reductase1.5.1.30.450
1og5SWFCytochrome P450 2C9/0.450
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.450
1tduCB3Thymidylate synthase/0.450
2acwUPGGlycosyltransferase/0.450
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.450
2pogWSTEstrogen receptor/0.450
2ylrFADPhenylacetone monooxygenase1.14.13.920.450
3qrwNDPPutative ketoacyl reductase1.3.10.450
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
3tqhNDPQuinone oxidoreductase/0.450
3zcw4A2Kinesin-like protein KIF11/0.450
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.450
4pd6URINucleoside permease/0.450
3reyXACAdenosine receptor A2a/0.450
1lhvNOGSex hormone-binding globulin/0.449
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2gtk208Peroxisome proliferator-activated receptor gamma/0.449
2vf0F89Thymidylate synthase/0.449
2znoS44Peroxisome proliferator-activated receptor gamma/0.449
3fwiCAMCamphor 5-monooxygenase1.14.15.10.449
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
4nr42LKCREB-binding protein/0.449
4riyADPEpidermal growth factor receptor2.7.10.10.449
4y8wSTRSteroid 21-hydroxylase/0.449
5eccNAPDehydrofolate reductase type I/0.449
5iubCLRAdenosine receptor A2a/0.449
5iu86DZAdenosine receptor A2a/0.449
1disBDMDihydrofolate reductase1.5.1.30.448
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.448
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.448
2qa2FADPolyketide oxygenase CabE/0.448
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.448
3cgoJNOMitogen-activated protein kinase 102.7.11.240.448
3fl8RARDihydrofolate reductase/0.448
3s79ASDAromatase1.14.14.140.448
3syiFADSulfide-quinone reductase/0.448
4p6xHCYGlucocorticoid receptor/0.448
5ii2LU2Protein polybromo-1/0.448
1eioGCHGastrotropin/0.447
1nvtNAPShikimate dehydrogenase (NADP(+))/0.447
2pzpACPFibroblast growth factor receptor 2/0.447
3da24MDCarbonic anhydrase 134.2.1.10.447
3oafOAGDihydrofolate reductase1.5.1.30.447
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.447
3qlrNDPDihydrofolate reductase1.5.1.30.447
3qm4PN0Cytochrome P450 2D6/0.447
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
3zoiM2WIsopenicillin N synthase1.21.3.10.447
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4hnc0UTMandelate racemase/0.447
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.447
4oze24GUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.447
4xumIMNPeroxisome proliferator-activated receptor gamma/0.447
5k2dZMAAdenosine receptor A2a/0.447
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.446
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2fk8SAMHydroxymycolate synthase MmaA42.1.10.446
2p5uNADUDP-glucose 4-epimerase/0.446
2qbnCAMCamphor 5-monooxygenase1.14.15.10.446
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.446
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3drcMTXDihydrofolate reductase1.5.1.30.446
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.446
3h18PMSEsterase/lipase/0.446
3h1jSMACytochrome b/0.446
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.446
3kytHC2Nuclear receptor ROR-gamma/0.446
3td8D2RDihydrofolate reductase1.5.1.30.446
3zk5Z18Cytochrome P450 monooxygenase PikC/0.446
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.446
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4xe606UDihydrofolate reductase1.5.1.30.446
4zowCLMMultidrug transporter MdfA/0.446
5dq8FLFTranscriptional enhancer factor TEF-4/0.446
4z34ON7Lysophosphatidic acid receptor 1/0.446
1dhjMTXDihydrofolate reductase1.5.1.30.445
1jpaANPEphrin type-B receptor 22.7.10.10.445
1qiqACCIsopenicillin N synthase1.21.3.10.445
1xqcAEJEstrogen receptor/0.445
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.445
2znq401Peroxisome proliferator-activated receptor delta/0.445
3clyACPFibroblast growth factor receptor 2/0.445
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.445
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3vt5YI2Vitamin D3 receptor/0.445
3vtcTK3Vitamin D3 receptor/0.445
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.445
4q71FADBifunctional protein PutA/0.445
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.445
1diuBDMDihydrofolate reductase1.5.1.30.444
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.444
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.444
2hw2RFPRifampin ADP-ribosyl transferase/0.444
2iviACWIsopenicillin N synthase1.21.3.10.444
3cyz9ODPheromone-binding protein ASP1/0.444
3tscNADUncharacterized protein/0.444
3ujlA8SAbscisic acid receptor PYL2/0.444
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.444
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.444
4ekkANPRAC-alpha serine/threonine-protein kinase2.7.11.10.444
4f640S8Fibroblast growth factor receptor 1/0.444
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ia3BIVVitamin D3 receptor A/0.444
4oavACP2-5A-dependent ribonuclease3.1.260.444
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.444
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.444
1ai9NDPDihydrofolate reductase1.5.1.30.443
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
1m13HYFNuclear receptor subfamily 1 group I member 2/0.443
1nzdUPGDNA beta-glucosyltransferase/0.443
1vj3TABDihydrofolate reductase1.5.1.30.443
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.443
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.443
2y03Y01Beta-1 adrenergic receptor/0.443
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.443
2z97CAMCamphor 5-monooxygenase1.14.15.10.443
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.443
3iaeD7KBenzaldehyde lyase/0.443
3icsADPCoenzyme A disulfide reductase/0.443
3w2o03PEpidermal growth factor receptor2.7.10.10.443
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.443
4jbtASDCytochrome P450 monooxygenase/0.443
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.443
4wloNAIMalate dehydrogenase, mitochondrial1.1.1.370.443
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.443
1aqbRTLRetinol-binding protein 4/0.442
1dz6CAMCamphor 5-monooxygenase1.14.15.10.442
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.442
1ot7IU5Bile acid receptor/0.442
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.442
2cig1DGDihydrofolate reductase1.5.1.30.442
2ft9CHDFatty acid-binding protein 2, liver/0.442
2po7CHDFerrochelatase, mitochondrial4.99.1.10.442
2q59240Peroxisome proliferator-activated receptor gamma/0.442
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2rhrEMOPutative ketoacyl reductase1.3.10.442
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3cv9VDXVitamin D3 dihydroxylase/0.442
3d7kD7KBenzaldehyde lyase/0.442
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3wd7COAAcridone synthase/0.442
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.442
4ele31IDihydrofolate reductase/0.442
4ib4ERM5-hydroxytryptamine receptor 2B/0.442
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1njsKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.441
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.441
1zs6ADPNucleoside diphosphate kinase 32.7.4.60.441
2a1nCAMCamphor 5-monooxygenase1.14.15.10.441
2gr1FADFerredoxin reductase/0.441
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.441
2j14GNIPeroxisome proliferator-activated receptor delta/0.441
2npaMMBPeroxisome proliferator-activated receptor alpha/0.441
2p15EZTEstrogen receptor/0.441
2y60M8FIsopenicillin N synthase1.21.3.10.441
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.441
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3opdHIEHeat shock protein 83/0.441
3uleC69Actin-related protein 3/0.441
4ejh0QACytochrome P450 2A131.14.14.10.441
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4hys1BJMitogen-activated protein kinase 82.7.11.240.441
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.441
4k2xFADPolyketide oxygenase/hydroxylase/0.441
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.441
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.441
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.441
1bk0ACVIsopenicillin N synthase1.21.3.10.440
1d7yFADFerredoxin reductase/0.440
1iwjCAMCamphor 5-monooxygenase1.14.15.10.440
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.440
1pg3PRXAcetyl-coenzyme A synthetase/0.440
1py5PY1TGF-beta receptor type-12.7.11.300.440
1rbqKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1tduDURThymidylate synthase/0.440
1ysx4EBSerum albumin/0.440
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.440
2z6dFMNPhototropin-22.7.11.10.440
3ctj320Hepatocyte growth factor receptor2.7.10.10.440
3hub469Mitogen-activated protein kinase 14/0.440
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.440
3v1nHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.440
3vspEK8Peroxisome proliferator-activated receptor gamma/0.440
3vucHHERenin3.4.23.150.440
3wsbRWZFarnesyltransferase, putative/0.440
4j6dTESCytochrome P450 monooxygenase/0.440
4nmdFDABifunctional protein PutA/0.440
4ztvTA7Anthranilate phosphoribosyltransferase/0.440
6cp4CAMCamphor 5-monooxygenase1.14.15.10.440