sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3m8c | EQU | Steroid Delta-isomerase | 5.3.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3m8c | EQU | Steroid Delta-isomerase | 5.3.3.1 | 1.000 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.467 | |
| 4l4x | NDP | AmphI | / | 0.465 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.459 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.450 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.448 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.447 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4hxy | NDP | Plm1 | / | 0.441 |