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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lt2FT3Enoyl-ACP reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lt2FT3Enoyl-ACP reductase/1.000
3lt0FT1Enoyl-ACP reductase/0.703
3lt1FT2Enoyl-ACP reductase/0.625
3am4FT1Enoyl-ACP reductase/0.619
3am3TCLEnoyl-ACP reductase/0.608
1nhgTCLEnoyl-ACP reductase/0.600
2o2yTCLEnoyl-ACP reductase/0.586
1nnuTCTEnoyl-ACP reductase/0.585
4igeCHJEnoyl-acyl carrier reductase/0.585
1zxlJP1Enoyl-ACP reductase/0.583
3f4bTCLEnoyl-acyl carrier protein reductase/0.580
3am5TCLEnoyl-ACP reductase/0.573
3lsyFT0Enoyl-ACP reductase/0.572
1zw1TN5Enoyl-ACP reductase/0.558
1uh5TCLEnoyl-ACP reductase/0.556
1nhwTCCEnoyl-ACP reductase/0.554
1zsnTN2Enoyl-ACP reductase/0.554
2foiJPAEnoyl-acyl carrier reductase/0.525
2op07PCEnoyl-ACP reductase/0.517
2o2sTCLEnoyl-acyl carrier reductase/0.510
2nq8ZIDEnoyl-ACP reductase/0.492
3nj8NJ8Enoyl-acyl carrier reductase/0.479
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1adfTADAlcohol dehydrogenase E chain1.1.1.10.446