sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3lov | FAD | Protoporphyrinogen oxidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3lov | FAD | Protoporphyrinogen oxidase | / | 1.000 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.496 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.482 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.457 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.454 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.451 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.450 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.448 | |
| 3ojl | NAD | Cap5O | / | 0.447 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.446 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 2ohx | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.441 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.440 |