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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3linE13Protease

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3linE13Protease/1.000
3liqE14Protease/0.607
3livE16Protease/0.592
3wsjMK1Protease/0.540
3litE15Protease/0.520
2aoe0Q4Gag-Pol polyprotein3.4.23.160.486
4kb9G79Protease/0.476
4hdfG52Gag-Pol polyprotein3.4.23.160.475
3ekp478Gag-Pol polyprotein3.4.23.160.468
2qd6065Gag-Pol polyprotein3.4.23.160.467
3lixE17Protease/0.461
2pk5075Protease/0.460
1ec2BEJGag-Pol polyprotein3.4.23.160.456
2xyfG40Gag-Pol polyprotein/0.456
3a2oKNJGag-Pol polyprotein3.4.23.160.453
3em4DR7Gag-Pol polyprotein3.4.23.160.453
1difA85Gag-Pol polyprotein/0.452
2uy0HV1Gag-Pol polyprotein3.4.23.160.452
2bqvA1AProtease/0.451
2cem2AHPol protein/0.450
3kdcJZPGag-Pol polyprotein3.4.23.160.449
2qnnQN1Gag-Pol polyprotein3.4.23.160.448
1ec3MS3Gag-Pol polyprotein3.4.23.160.447
2ieo017Protease/0.447
1ivp1ZKGag-Pol polyprotein/0.446
3hzc2NCProtease/0.446
1w5yBE6Gag-Pol polyprotein3.4.23.160.444
3ekqROCGag-Pol polyprotein3.4.23.160.444
3zpsEQMGag-Pol polyprotein3.4.23.160.444
1hvjA78Gag-Pol polyprotein/0.443
2idw017Protease/0.443
2p3b3TLV-1 PROTEASE protein/0.441
2p3b3TLV-1 protease/0.441