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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lgp50XDisintegrin and metalloproteinase domain-containing protein 173.4.24.86

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lgp50XDisintegrin and metalloproteinase domain-containing protein 173.4.24.861.000
3b92440Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.499
2i47INNDisintegrin and metalloproteinase domain-containing protein 173.4.24.860.492
3kmc403Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.483
3le9727Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.464
2j14GNIPeroxisome proliferator-activated receptor delta/0.462
2i47KGYDisintegrin and metalloproteinase domain-containing protein 173.4.24.860.461
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
3kmeINNDisintegrin and metalloproteinase domain-containing protein 173.4.24.860.451
2znq401Peroxisome proliferator-activated receptor delta/0.448
3l0v724Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.448
2znpK55Peroxisome proliferator-activated receptor delta/0.447
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.446
1zxcIH6Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.443
1y0s331Peroxisome proliferator-activated receptor delta/0.441