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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lfsA07Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lfsA07Cyclin-dependent kinase 22.7.11.221.000
3lfqA28Cyclin-dependent kinase 22.7.11.220.607
4fki09KCyclin-dependent kinase 22.7.11.220.501
3qwjX6ACyclin-dependent kinase 22.7.11.220.488
2j9mPY8Cyclin-dependent kinase 22.7.11.220.482
3le62BZCyclin-dependent kinase 22.7.11.220.470
2r3mSCXCyclin-dependent kinase 22.7.11.220.463
3r7yZ04Cyclin-dependent kinase 22.7.11.220.459
3r7iX9ICyclin-dependent kinase 22.7.11.220.458
2r3p3SCCyclin-dependent kinase 22.7.11.220.457
4ek610KCyclin-dependent kinase 22.7.11.220.457
2fvdLIACyclin-dependent kinase 22.7.11.220.455
3s2pPMUCyclin-dependent kinase 22.7.11.220.453
2w1hL0FCyclin-dependent kinase 22.7.11.220.451
2a0cCK9Cyclin-dependent kinase 22.7.11.220.444
3lfnA27Cyclin-dependent kinase 22.7.11.220.444
2w05FRTCyclin-dependent kinase 22.7.11.220.443
1oitHDTCyclin-dependent kinase 22.7.11.220.442
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.440